Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vicki L, Locke"'
Publikováno v:
PROTEOMICS. 2:1254-1260
The Gradiflow trade mark, a preparative electrophoresis instrument capable of separating proteins on the basis of their size or charge, was used to separate whole cell lysates, prepared from bakers yeast (Saccharomyces cerevisiae) and Chinese snow pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9068226a93c83fbf33b55e3784f166b5
https://doi.org/10.1002/1615-9861(200209)2:9<1254::aid-prot1254>3.0.co
https://doi.org/10.1002/1615-9861(200209)2:9<1254::aid-prot1254>3.0.co
Publikováno v:
British Journal of Haematology. 106:86-91
Relative to the commonly used anthracyclines, little is known about idarubicin and the development of multidrug resistance. We have previously shown the K562/IDA subline resulting from intermittent treatment of the K562 human leukaemia cell line with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fc40cd0ed3611210eaa1321ace5fc2
https://doi.org/10.1046/j.1365-2141.1999.01494.x
https://doi.org/10.1046/j.1365-2141.1999.01494.x
Autor:
Mark J. Raftery, Michael Guilhaus, Valerie C. Wasinger, Irene Bate, Deborah L. Rothemund, Mark Larance, Vicki L. Locke, Audrey Liew
Publikováno v:
Proteomics. 5(13)
One of the major challenges facing protein analysis is the dynamic range of protein expression within massively complex samples (Corthals, G. L. et al.., Electrophoresis 2000, 21, 1104–1115). In plasma this difference is as great as ten orders of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc78b946f81988f6859a99809c1982a
https://pubmed.ncbi.nlm.nih.gov/16104060
https://pubmed.ncbi.nlm.nih.gov/16104060
Publikováno v:
Anticancer research. 24(2A)
The H69-EPR, H69-CP, H69-VP and H69/R38 resistant sublines of the classic small cell lung cancer (SCLC) line have proven useful in studies of resistance and its circumvention with paclitaxel.The suppressor/oncogene profile of these sublines determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ab543feb79ee2c420c8041963c7b45f
https://pubmed.ncbi.nlm.nih.gov/15152945
https://pubmed.ncbi.nlm.nih.gov/15152945
Publikováno v:
Anti-cancer drugs. 14(7)
Small cell lung cancer (SCLC) responds to treatment with cisplatin and etoposide, but relapse is rapid and survival rates are low. Our aims were to determine the mechanisms of resistance and the potential for paclitaxel (Taxol) to overcome any drug o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cc772f060a8f29bea5608c8ff43253
https://pubmed.ncbi.nlm.nih.gov/12960736
https://pubmed.ncbi.nlm.nih.gov/12960736
Autor:
Deborah L. Rothemund, Valerie C. Wasinger, Theresa M. Thomas, Dennis B Rylatt, Vicki L. Locke, Audrey Liew
Publikováno v:
Proteomics. 3(3)
Analysis of complex protein samples by two-dimensional electrophoresis (2-DE) is often more difficult in the presence of a few predominant proteins. In plasma, proteins such as albumin mask proteins of lower abundance, as well as significantly limiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89588c67094d5dc964d46e2130580932
https://pubmed.ncbi.nlm.nih.gov/12627381
https://pubmed.ncbi.nlm.nih.gov/12627381
Publikováno v:
Proteomics. 2(9)
The Gradiflow trade mark, a preparative electrophoresis instrument capable of separating proteins on the basis of their size or charge, was used to separate whole cell lysates, prepared from bakers yeast (Saccharomyces cerevisiae) and Chinese snow pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::173094275e1403e77b32a1858989a96a
https://pubmed.ncbi.nlm.nih.gov/12362343
https://pubmed.ncbi.nlm.nih.gov/12362343
Background Recent studies have shown that paclitaxel (Taxol) is an active chemotherapeutic in the treatment of small cell lung cancer. Paclitaxel binds to tubulin and prevents depolymerization. This causes cells to arrest in the G2/M phase of the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a9378d916dd1c92d46f41945f221e9
https://hdl.handle.net/10453/3697
https://hdl.handle.net/10453/3697
Autor:
Vicki L. Locke, Theresa M. Thomas
Publikováno v:
Cold Spring Harbor Protocols. 2006:pdb.prot4236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f1d185c22a2fb1cfd5f022a3d9642d
https://doi.org/10.1101/pdb.prot4236
https://doi.org/10.1101/pdb.prot4236
Autor:
Theresa M. Thomas, Vicki L. Locke
Publikováno v:
Cold Spring Harbor Protocols. 2006:pdb.prot4237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0948dabd09f95d5b79a19ee70b7a07
https://doi.org/10.1101/pdb.prot4237
https://doi.org/10.1101/pdb.prot4237