Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Vicki Huff"'
Autor:
Andrew J. Murphy, Changde Cheng, Justin Williams, Timothy I. Shaw, Emilia M. Pinto, Karissa Dieseldorff-Jones, Jack Brzezinski, Lindsay A. Renfro, Brett Tornwall, Vicki Huff, Andrew L. Hong, Elizabeth A. Mullen, Brian Crompton, Jeffrey S. Dome, Conrad V. Fernandez, James I. Geller, Peter F. Ehrlich, Heather Mulder, Ninad Oak, Jamie Maciezsek, Carolyn M. Jablonowski, Andrew M. Fleming, Prahalathan Pichavaram, Christopher L. Morton, John Easton, Kim E. Nichols, Michael R. Clay, Teresa Santiago, Jinghui Zhang, Jun Yang, Gerard P. Zambetti, Zhaoming Wang, Andrew M. Davidoff, Xiang Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Developing synchronous bilateral Wilms tumor suggests an underlying (epi)genetic predisposition. Here, we evaluate this predisposition in 68 patients using whole exome or genome sequencing (n = 85 tumors from 61 patients with matched germlin
Externí odkaz:
https://doaj.org/article/946f460fad5e41959f9465bb4f236137
Autor:
Chiara Mariottini, Leonardo Munari, Ellen Gunzel, Joseph M. Seco, Nikos Tzavaras, Jens Hansen, Sarah A. Stern, Virginia Gao, Hossein Aleyasin, Ali Sharma, Evren U. Azeloglu, Georgia E. Hodes, Scott J. Russo, Vicki Huff, Marc R. Birtwistle, Robert D. Blitzer, Cristina M. Alberini, Ravi Iyengar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Impairments in memory flexibility are associated with neuropsychiatric disorders such as PTSD and autism. Here, the authors report that the transcriptional repressor Wilm's Tumor 1 regulates synaptic plasticity leading to weakening of memory strength
Externí odkaz:
https://doaj.org/article/aaada62663944bd6bb6bd2a1e13d925c
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 2, Pp 71-81 (2016)
Wilms tumor, a common childhood tumor of the kidney, is thought to arise from undifferentiated renal mesenchyme. Variable tumor histology and the identification of tumor subsets displaying different gene expression profiles suggest that tumors may ar
Externí odkaz:
https://doaj.org/article/f20f607800c04f12b33d1028110bdca9
Autor:
Amy E Armstrong, Samantha Gadd, Vicki Huff, Daniela S Gerhard, Jeffrey S Dome, Elizabeth J Perlman
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208936 (2018)
This study explores the genomic alterations that contribute to the formation of a unique subset of low-risk, epithelial differentiated, favorable histology Wilms tumors (WT), tumors that have been characterized by their expression of post-induction r
Externí odkaz:
https://doaj.org/article/b4297202c4ee46a484b18f0b7575a015
Autor:
Paramahamsa Maturu, Willem W. Overwijk, John Hicks, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Vicki Huff
Publikováno v:
Translational Oncology, Vol 7, Iss 4, Pp 484-492 (2014)
The role of inflammation in cancer has been reported in various adult malignant neoplasms. By contrast, its role in pediatric tumors has not been as well studied. In this study, we have identified and characterized the infiltration of various inflamm
Externí odkaz:
https://doaj.org/article/e65787e80a784e30940235f7bd4afe97
Autor:
Rachel Shukrun, Naomi Pode-Shakked, Oren Pleniceanu, Dorit Omer, Einav Vax, Eyal Peer, Sara Pri-Chen, Jasmine Jacob, Qianghua Hu, Orit Harari-Steinberg, Vicki Huff, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 24-33 (2014)
An open question remains in cancer stem cell (CSC) biology whether CSCs are by definition at the top of the differentiation hierarchy of the tumor. Wilms’ tumor (WT), composed of blastema and differentiated renal elements resembling the nephrogenic
Externí odkaz:
https://doaj.org/article/b7664ab913154a2d8af8c12f9ddde693
Autor:
Samantha Gadd, Vicki Huff, Chiang-Ching Huang, E. Cristy Ruteshouser, Jeffrey S. Dome, Paul E. Grundy, Norman Breslow, Lawrence Jennings, Daniel M. Green, J. Bruce Beckwith, Elizabeth J. Perlman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 742-756 (2012)
Wilms tumors (WT) have provided broad insights into the interface between development and tumorigenesis. Further understanding is confounded by their genetic, histologic, and clinical heterogeneity, the basis of which remains largely unknown. We eval
Externí odkaz:
https://doaj.org/article/645ccf46a1b8404b9235379f5a0e3b1f
Autor:
Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang, Ya Qing Wang, Min Chen, Jun Zhang, Jian Xiu Hao, Yan Bo Wang, Ri Na Sha, Yi Huang, Xiao Liu, Jing Chu Hu, Guang Qing Sun, Hong Gang Li, Cheng Liang Xiong, Jun Xie, Zhi Mao Jiang, Zhi Ming Cai, Jun Wang, Jian Wang, Vicki Huff, Yao Ting Gui, Fei Gao
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003645 (2013)
Azoospermia is one of the major reproductive disorders which cause male infertility in humans; however, the etiology of this disease is largely unknown. In the present study, six missense mutations of WT1 gene were detected in 529 human patients with
Externí odkaz:
https://doaj.org/article/3086d3b774f84117bb6e630209efe335
Autor:
Elizabeth J. Perlman, Julie M. Gastier-Foster, Nicole Ross, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Amy L. Walz, Oliver A. Hampton, David A. Wheeler, Jing Ma, Charles G. Mullighan, James I. Geller, Jing Tian, Yueh-Yun Chi, Jeffrey S. Dome, Vicki Huff, Marco A. Marra, Richard A. Moore, Andrew J. Mungall, Zusheng Zong, Yussanne Ma, Ying Hu, Cu Nguyen, Chunhua Yan, Chih Hao Hsu, Qing-Rong Chen, Daoud Meerzaman, Jaime M. Guidry Auvil, Malcolm A. Smith, Daniela S. Gerhard, Samantha Gadd, Ariadne H.A.G. Ooms
Purpose: To investigate the role and significance of TP53 mutation in diffusely anaplastic Wilms tumors (DAWTs).Experimental Design: All DAWTs registered on National Wilms Tumor Study-5 (n = 118) with available samples were analyzed for TP53 mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e5ffc41c18b2d4c2506525d3dba9a1
https://doi.org/10.1158/1078-0432.c.6524982
https://doi.org/10.1158/1078-0432.c.6524982
Autor:
Micheala A. Aldred, Chris Jones, Vicki Huff, Jeffrey Dome, Paul Grundy, Kathy Pritchard-Jones, Manfred Gessler, Jenny Wegert, Phyllis Harbor, Rachael Natrajan, E. Cristy Ruteshouser, Kylie M. Drake
Supplementary Data from Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660cda499ca9a86e63ef7f8e275906a8
https://doi.org/10.1158/1078-0432.22440630.v1
https://doi.org/10.1158/1078-0432.22440630.v1