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pro vyhledávání: '"Vicki Gupta"'
Autor:
Vicki Gupta, Michael T. Kennedy, Ping Gao, Nidhi Mahajan, Sekhar Surapaneni, Lan Li, Chandra Ma, Alana Ali-Reynolds, Anna Akrami, Jack Hu, Ben Chal
Publikováno v:
Molecular Pharmaceutics. 5:981-993
Amorphous solid dispersions (ASD) of a poorly soluble water-soluble VR1 antagonist (AMG 517) were explored for improving physical stability and in vivo exposure. AMG 517 was incorporated at 15 or 50 wt % into polymeric microparticles of hydroxypropyl
Autor:
Hossein Zia, Henry T. Gaud, Linda A. Lanaski, Vicki Gupta, Robert E. Johnson, Thomas E. Needham, Martin J. Griffin
Publikováno v:
Journal of Controlled Release. 17:61-67
The stability ofatriopeptin III (APIII) encapsulated in poly ( d,l -lactide-co-glycolide) (PLGA) microspheres has been investigated and compared to the stability of APIII alone. When the microspheres are shaken in Tris-buffered Ringer's (pH 7.4) at 4