Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vicente Roca Agujetas"'
Autor:
Cristina de Dios, Xenia Abadin, Vicente Roca-Agujetas, Marina Jimenez-Martinez, Albert Morales, Ramon Trullas, Montserrat Mari, Anna Colell
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-23 (2023)
Abstract Background Persistent inflammatory response in the brain can lead to tissue damage and neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of inflammasomes, molecular platforms that drive inflammation through casp
Externí odkaz:
https://doaj.org/article/d67c08fc39e14f8ea51fdd4ce91c409e
Autor:
Vicente Roca-Agujetas, Elisabet Barbero-Camps, Cristina de Dios, Petar Podlesniy, Xenia Abadin, Albert Morales, Montserrat Marí, Ramon Trullàs, Anna Colell
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-26 (2021)
Abstract Background Emerging evidence indicates that impaired mitophagy-mediated clearance of defective mitochondria is a critical event in Alzheimer’s disease (AD) pathogenesis. Amyloid-beta (Aβ) metabolism and the microtubule-associated protein
Externí odkaz:
https://doaj.org/article/cf8bece26c454c00987590519a3d4eb7
Autor:
Cristina de Dios, Isabel Bartolessis, Vicente Roca-Agujetas, Elisabet Barbero-Camps, Montserrat Mari, Albert Morales, Anna Colell
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Familial early-onset forms of Alzheimer's disease (AD) are linked to overproduction of amyloid beta (Aβ) peptides, while decreased clearance of Aβ is the driving force leading to its toxic accumulation in late-onset (sporadic) AD. Oxidative modific
Externí odkaz:
https://doaj.org/article/1fccda202b424c0686be75198c797c37
Autor:
Montserrat Marí, Estefanía de Gregorio, Cristina de Dios, Vicente Roca-Agujetas, Blanca Cucarull, Anna Tutusaus, Albert Morales, Anna Colell
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 909 (2020)
Mitochondria are the main source of reactive oxygen species (ROS), most of them deriving from the mitochondrial respiratory chain. Among the numerous enzymatic and non-enzymatic antioxidant systems present in mitochondria, mitochondrial glutathione (
Externí odkaz:
https://doaj.org/article/82adc64b9a4145dba6fdf4d443788c08
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Mitochondrial dysfunction is behind several neurodegenerative diseases, including Alzheimer disease (AD). Accumulation of damaged mitochondria is already observed at the early stages of AD and has been linked to impaired mitophagy, but the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c39fbc9206ac34b8be400899757046
https://doi.org/10.1080/15548627.2021.1920814
https://doi.org/10.1080/15548627.2021.1920814
Autor:
Anna Colell, Elisabet Barbero-Camps, Ramon Trullas, Albert Morales, Vicente Roca-Agujetas, Cristina de Dios, Montserrat Marí, Xenia Abadin, Petar Podlesniy
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-26 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurodegeneration
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurodegeneration
Background: Emerging evidence indicates that impaired mitophagy-mediated clearance of defective mitochondria is a critical event in Alzheimer’s disease (AD) pathogenesis. Amyloid-beta (Aβ) metabolism and the microtubule-associated protein tau have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d8bba66f73b9392ac044c909a0f1ac
http://hdl.handle.net/10261/260208
http://hdl.handle.net/10261/260208
Autor:
Albert Morales, Estefanía de Gregorio, Vicente Roca-Agujetas, Anna Tutusaus, Montserrat Marí, Anna Colell, Blanca Cucarull, Cristina de Dios
Publikováno v:
Antioxidants
Antioxidants, Vol 9, Iss 909, p 909 (2020)
Antioxidants, Vol 9, Iss 909, p 909 (2020)
Mitochondria are the main source of reactive oxygen species (ROS), most of them deriving from the mitochondrial respiratory chain. Among the numerous enzymatic and non-enzymatic antioxidant systems present in mitochondria, mitochondrial glutathione (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a38c995f11d8194fc0fa77fedd91d08
http://hdl.handle.net/10261/233389
http://hdl.handle.net/10261/233389
Autor:
Vicente Roca-Agujetas, Elisabet Barbero-Camps, Cristina de Dios, Petar Podlesniy, Albert Morales, Montserrat Marí, Ramon Trullàs, Anna Colell Riera
Background: Emerging evidence indicates that impaired mitophagy-mediated clearance of defective mitochondria is a critical event in Alzheimer’s disease (AD) pathogenesis. Amyloid-beta (A) metabolism and the microtubule-associated protein tau hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c2eb0ea3aeed1512145249b9ec742a2
https://doi.org/10.21203/rs.3.rs-69969/v1
https://doi.org/10.21203/rs.3.rs-69969/v1
Autor:
Anil Paul Chirackal Manavalan, Anna Colell, Yidan Sun, Ute Panzenboeck, Nicole Maria Albrecher, Ernst Malle, Elham Fanaee-Danesh, Vicente Roca Agujetas, Martina Zandl-Lang, Frank Madeo, Jelena Tadic, Anika Stracke, Carmen Tam-Amersdorfer, Marielies Reiter, Cristina de Dios, Chaitanya Chakravarthi Gali, Alexandra Kober
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The pathogenesis of Alzheimer's disease (AD) is characterized by overproduction, impaired clearance, and deposition of amyloid-β peptides (Aβ) and connected to cholesterol homeostasis. Since the blood-brain barrier (BBB) is involved in these proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdd79645719e9a81015558563212893
http://hdl.handle.net/10261/201312
http://hdl.handle.net/10261/201312
Autor:
Albert Morales, Laura Lestón, Montserrat Marí, Vicente Roca-Agujetas, Cristina de Dios, Anna Colell
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Hindawi Oxidative Medicine and Cellular Longevity
instname
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Hindawi Oxidative Medicine and Cellular Longevity
Autophagy is a self-digestive process that degrades intracellular components, including damaged organelles, to maintain energy homeostasis and to cope with cellular stress. Autophagy plays a key role during development and adult tissue homeostasis, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e989ebe3ee3f5a87546282024c5560e0
http://hdl.handle.net/10261/205181
http://hdl.handle.net/10261/205181