Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Vicente Marchán"'
Autor:
Sergi Chumillas, Saurabh Loharch, Manuela Beltrán, Mateusz P. Szewczyk, Silvia Bernal, Maria C. Puertas, Javier Martinez-Picado, José Alcamí, Luis M. Bedoya, Vicente Marchán, José Gallego
Publikováno v:
Molecules, Vol 28, Iss 20, p 7031 (2023)
Human immunodeficiency virus-type 1 (HIV-1) remains one of the leading contributors to the global burden of disease, and novel antiretroviral agents with alternative mechanisms are needed to cure this infection. Here, we describe an exploratory attem
Externí odkaz:
https://doaj.org/article/d18d42978e3647e197f011f1c2e7ef62
Autor:
Joaquín Bonelli, María Velasco-de Andrés, Neus Isidro, Cristina Bayó, Sergi Chumillas, Laura Carrillo-Serradell, Sergi Casadó-Llombart, Cheryl Mok, Daniel Benítez-Ribas, Francisco Lozano, Josep Rocas, Vicente Marchán
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 58 (2022)
Encapsulation of water-soluble bioactive compounds for enabling specific accumulation in tumor locations, while avoiding premature clearance and/or degradation in the bloodstream, is one of the main hallmarks in nanomedicine, especially that of NIR f
Externí odkaz:
https://doaj.org/article/40adc6dc96854439a914bcdbba777c1f
Autor:
Alvaro Simba-Lahuasi, Ángel Cantero-Camacho, Romel Rosales, Briana Lynn McGovern, M. Luis Rodríguez, Vicente Marchán, Kris M. White, Adolfo García-Sastre, José Gallego
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1448 (2022)
Antiviral agents are needed for the treatment of SARS-CoV-2 infections and to control other coronavirus outbreaks that may occur in the future. Here we report the identification and characterization of RNA-binding compounds that inhibit SARS-CoV-2 re
Externí odkaz:
https://doaj.org/article/77d3fb81def04231933af5b1d52dd72e
Autor:
Eduardo Izquierdo, Marta López-Corrales, Diego Abad-Montero, Anna Rovira, Gemma Fabriàs, Manel Bosch, José Luís Abad, Vicente Marchán
Publikováno v:
The Journal of Organic Chemistry. 87:16351-16367
Ceramides (Cer) are bioactive sphingolipids that have been proposed as potential disease biomarkers since they are involved in several cellular stress responses, including apoptosis and senescence. 1-Deoxyceramides (1-deoxyCer), a particular subtype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6af619272089e86a1d2f39dd140bf1
https://doi.org/10.1021/acs.joc.2c02019
https://doi.org/10.1021/acs.joc.2c02019
Autor:
Joaquín Bonelli, Enrique Ortega-Forte, Anna Rovira, Manel Bosch, Oriol Torres, Cristina Cuscó, Josep Rocas, José Ruiz, Vicente Marchán
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Integration of photosensitizers (PSs) within nanoscale delivery systems offers great potential for overcoming some of the 'Achiles' heels' of photodynamic therapy (PDT). Herein, we have encapsulated a mitochondria-targeted coumarin PS into amphoteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d105d0d5676cdd16b07b2be4fab2dea
https://doi.org/10.1021/acs.biomac.2c00361
https://doi.org/10.1021/acs.biomac.2c00361
Autor:
Marta López-Corrales, Anna Rovira, Albert Gandioso, Santi Nonell, Manel Bosch, Vicente Marchán
Publikováno v:
The Journal of Organic Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4beeb9f8d1fedbd544e3f1962ff38386
https://doi.org/10.1021/acs.joc.3c00387
https://doi.org/10.1021/acs.joc.3c00387
Autor:
Joaquín Bonelli, Enrique Ortega-Forte, Gloria Vigueras, Manel Bosch, Natalia Cutillas, Josep Rocas, José Ruiz, Vicente Marchán
Publikováno v:
Inorganic Chemistry Frontiers. 9:2123-2138
Cyclometalated Ir(III) complexes hold great promise as an alternative to platinum metallodrugs for the therapy and diagnosis of cancer. However, their low aqueous solubility and poor cell membrane permeability are obstacles for in vivo applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46685c8cb0dec0a2672802fea64173cf
https://doi.org/10.1039/d1qi01542g
https://doi.org/10.1039/d1qi01542g
Autor:
Anna Rovira, Manel Bosch, Vicente Marchán, Santi Nonell, Marta López-Corrales, Albert Gandioso
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Although photolabile protecting groups (PPGs) have found widespread applications in several fields of chemistry, biology and materials science, there is a growing interest in expanding the photochemical toolbox to overcome some of the limitations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853c8d680b29df3c4702516fd3402b83
https://doi.org/10.1002/chem.202002314
https://doi.org/10.1002/chem.202002314
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
We describe a novel transition metal-free method for the synthesis of N-difluoromethylated pyridines and 4-pyridones/quinolones by using readily available ethyl bromodifluoroacetate as a fluorine source. The formation of N-difluoromethylated pyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12922af5580bfbe2e85af8dae252c3ae
https://doi.org/10.1039/d0ra06322c
https://doi.org/10.1039/d0ra06322c
Autor:
Vicente Marchán, Joaquín Bonelli, Enrique Ortega-Forte, José Ruiz, Anna Rovira, Manel Bosch, Albert Gandioso
Publikováno v:
Journal of Medicinal Chemistry
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Photodynamic therapy (PDT) for cancer treatment has drawn increased attention over the last decades. Herein, we introduce a novel family of low-molecular-weight coumarins as potential PDT anticancer tools. Through a systematic study with a library of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8d6b052db1b4b49303cab45626cf21
http://hdl.handle.net/2445/183273
http://hdl.handle.net/2445/183273
