Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vicente J. Planelles-Herrero"'
Autor:
Louise Canon, Carlos Kikuti, Vicente J. Planelles-Herrero, Tianming Lin, Franck Mayeux, Helena Sirkia, Young il Lee, Leila Heidsieck, Léonid Velikovsky, Amandine David, Xiaoyan Liu, Dihia Moussaoui, Emma Forest, Peter Höök, Karl J. Petersen, Tomos E. Morgan, Aurélie Di Cicco, Julia Sirés-Campos, Emmanuel Derivery, Daniel Lévy, Cédric Delevoye, H. Lee Sweeney, Anne Houdusse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Myosin VI (Myo6) is the only minus-end directed nanomotor on actin, allowing it to uniquely contribute to numerous cellular functions. As for other nanomotors, the proper functioning of Myo6 relies on precise spatiotemporal control of motor
Externí odkaz:
https://doaj.org/article/9c1a197ee24d4bfc8261601e8244d9ad
Autor:
Vicente J. Planelles-Herrero, James J. Hartman, Julien Robert-Paganin, Fady I. Malik, Anne Houdusse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Omecamtiv mecarbil (OM) is a cardiac myosin activator that is currently in clinical trials for heart failure treatment. Here, the authors give insights into its mode of action and present the crystal structure of OM bound to bovine cardiac myosin, wh
Externí odkaz:
https://doaj.org/article/e89f50badcf146dca49a24d78e0e1fa7
Autor:
I-Mei Yu, Vicente J. Planelles-Herrero, Yannick Sourigues, Dihia Moussaoui, Helena Sirkia, Carlos Kikuti, David Stroebel, Margaret A. Titus, Anne Houdusse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Cadherin is essential for mechanotransduction and myosin-adaptor-harmonin complexes anchor it to actin. Here the authors present the structures of myosin 7 MF2 domains bound to the harmonin PDZ3c domain and give insights into myosin-adaptor-harmonin
Externí odkaz:
https://doaj.org/article/aa24a24d03664dbc891f02ce9745c6cd
Autor:
Cécile Dubois, Vicente J. Planelles-Herrero, Camille Tillatte-Tripodi, Stéphane Delbecq, Léa Mammri, Elena M. Sirkia, Virginie Ropars, Christian Roumestand, Philippe Barthe
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3597 (2021)
When combined with NMR spectroscopy, high hydrostatic pressure is an alternative perturbation method used to destabilize globular proteins that has proven to be particularly well suited for exploring the unfolding energy landscape of small single-dom
Externí odkaz:
https://doaj.org/article/daee2a44d9d748b88f733c7658436d8a
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovic, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
SUMMARYThe Commander complex is required for endosomal recycling of diverse transmembrane cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two subassemblies; Retriever composed of VPS35L, VPS26C and VPS29, and the CCC complex which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d210a5342199c943249b9d1af8c0d6
https://doi.org/10.2139/ssrn.4330804
https://doi.org/10.2139/ssrn.4330804
Autor:
Dina J. Ashour, Clinton H. Durney, Vicente J. Planelles-Herrero, Tim J. Stevens, James J. Feng, Katja Röper
Peer reviewed: True
Acknowledgements: The authors thank Frieder Schöck, Debbie Andrew, Magali Suzanne and Isabel Palacios for fly stocks, Emmanuel Derivery for reagents and members of the lab and Cell Biology division for input on the manuscrip
Acknowledgements: The authors thank Frieder Schöck, Debbie Andrew, Magali Suzanne and Isabel Palacios for fly stocks, Emmanuel Derivery for reagents and members of the lab and Cell Biology division for input on the manuscrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c74a93ae8687ad5aacf19b0f10fa0b9
https://doi.org/10.1101/2022.10.11.511783
https://doi.org/10.1101/2022.10.11.511783
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovič, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
Publikováno v:
Cell. 186:2219-2237.e29
Publikováno v:
The EMBO Journal. 40
The TRAPP complexes are nucleotide exchange factors that play essential roles in membrane traffic and autophagy. TRAPPII activates Rab11, and TRAPPIII activates Rab1, with the two complexes sharing a core of small subunits that affect nucleotide exch
SummaryThe TRAPP complexes are highly conserved nucleotide exchange factors, with TRAPPIII activating Rab1 and TRAPPII acting primarily on Rab11. The two complexes share a core of small subunits that affect nucleotide exchange, but are distinguished
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f466fb5fe49ce975d47255ee652bd303
https://doi.org/10.1101/2020.12.17.423307
https://doi.org/10.1101/2020.12.17.423307
Autor:
Julien Robert-Paganin, Vicente J. Planelles-Herrero, James J. Hartman, Fady I. Malik, Anne Houdusse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
'Nature Communications ', vol: 8, pages: 190-1-190-10 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-00176-5⟩
'Nature Communications ', vol: 8, pages: 190-1-190-10 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-00176-5⟩
Omecamtiv mecarbil is a selective, small-molecule activator of cardiac myosin that is being developed as a potential treatment for heart failure with reduced ejection fraction. Here we determine the crystal structure of cardiac myosin in the pre-powe