Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vicente Castro-Castillo"'
Autor:
Patricio Sáez-Briones, Vicente Castro-Castillo, Gabriela Díaz-Véliz, Luis Valladares, Rafael Barra, Alejandro Hernández, Bruce K. Cassels
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. Nevertheless, the roles of sp
Externí odkaz:
https://doaj.org/article/0d49ae635a7247d2a84373f0d5b0c631
Autor:
Sebastián Fuentes-Retamal, Cristian Sandoval-Acuña, Liliana Peredo-Silva, Daniela Guzmán-Rivera, Mario Pavani, Natalia Torrealba, Jaroslav Truksa, Vicente Castro-Castillo, Mabel Catalán, Ulrike Kemmerling, Félix A. Urra, Jorge Ferreira
Publikováno v:
Cells, Vol 9, Iss 2, p 407 (2020)
The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound, 10-((2,5-dihydroxybenzoyl)oxy)decy
Externí odkaz:
https://doaj.org/article/ad9dfadaf95b4e179a64172908555aa6
Autor:
Leonel A Cortes, Lorena Castro, Bárbara Pesce, Juan D Maya, Jorge Ferreira, Vicente Castro-Castillo, Eduardo Parra, José A Jara, Rodrigo López-Muñoz
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136852 (2015)
disease is one of the most neglected tropical diseases in the world, affecting nearly 15 million people, primarily in Latin America. Only two drugs are used for the treatment of this disease, nifurtimox and benznidazole. These drugs have limited effi
Externí odkaz:
https://doaj.org/article/bf600f884ddd4010ae450b5345fb15ba
Autor:
Jocelyn Aguilera, Vicente Castro-Castillo, Charlotte Palominos, Ricardo Ramires-Fernandez, Javier Gajardo-de la Fuente, Jorge Ferreira, Mabel Catalán, Ivonne Olmedo, José A. Souto, Marta Domínguez, José A. Jara, Marcelo Valencia, Alfredo Molina-Berríos
Publikováno v:
RSC Med Chem
Continuous flow chemistry was used for the synthesis of a series of delocalized lipophilic triphenylphosphonium cations (DLCs) linked by means of an ester functional group to several hydroxylated benzoic acid derivatives and evaluated in terms of bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a14d4546e3e2904c38eb026228326e
https://pubmed.ncbi.nlm.nih.gov/33479625
https://pubmed.ncbi.nlm.nih.gov/33479625
Autor:
Jaroslav Truksa, Ulrike Kemmerling, Natalia Torrealba, Cristian Sandoval-Acuña, Jorge Ferreira, Vicente Castro-Castillo, Sebastián Fuentes-Retamal, Mario Pavani, Liliana Peredo-Silva, Mabel Catalán, Daniela Guzmán-Rivera, Félix A. Urra
Publikováno v:
Cells, Vol 9, Iss 2, p 407 (2020)
Cells
Volume 9
Issue 2
Cells
Volume 9
Issue 2
The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound, 10-((2,5-dihydroxybenzoyl)oxy)decy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff94b60b11f43b75ac6888df65e032c8
https://www.mdpi.com/2073-4409/9/2/407
https://www.mdpi.com/2073-4409/9/2/407
Autor:
Solange Rebolledo, Cristian Sandoval-Acuña, Jorge Ferreira, Juan Diego Maya, Sebastián Fuentes-Retamal, Matías Madrid-Rojas, Vicente Castro-Castillo, Mario Pavani, Ulrike Kemmerling, Eduardo Parra, Liliana Peredo-Silva
Publikováno v:
Toxicology and Applied Pharmacology. 329:334-346
We previously demonstrated that alkyl gallates coupled to triphenylphosphine have a selective and efficient antiproliferative effect by inducing mitochondrial uncoupling in vitro due to the increased mitochondrial transmembrane potential of tumor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366bc30f8591b6fdce978dc765189d08
https://doi.org/10.1016/j.taap.2017.06.017
https://doi.org/10.1016/j.taap.2017.06.017
Publikováno v:
Chemistry of Heterocyclic Compounds. 53:553-559
We followed a simple, inexpensive, and efficient route to synthesize a series of 3,4-dihydrobenzo[f]quinoxalin-6(2H)-one derivatives substituted in the ring B, with the expectation that this scaffold might exhibit antineoplastic activity. 5-Chloroben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51211db1d1895c9fcfa2e0fcae2eeb0
https://doi.org/10.1007/s10593-017-2092-y
https://doi.org/10.1007/s10593-017-2092-y
Autor:
Cristian Sandoval-Acuña, Daniela Guzmán-Rivera, Ana Liempi, Liliana Peredo-Silva, Vicente Castro-Castillo, Ulrike Kemmerling, Sebastián Fuentes-Retamal, Mabel Catalán, Jorge F. Ferreira, Mario Pavani
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a8489da5a9ae4f72a190a8562488e2
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-6-49
https://doi.org/10.1254/jpssuppl.wcp2018.0_po4-6-49
Autor:
Enrico Gratton, Vicente Castro-Castillo, Catalina Sandoval-Altamirano, Germán Günther, Leonel Malacrida, Javier Gajardo, Susana A. Sanchez
Publikováno v:
J Mater Chem B
We synthesized an anthracene derivative with solvatochromic properties to be used as a molecular probe for membrane dynamics and supramolecular organization. A ten carbon atom acyl chain and a dimethylamino substitution were introduced at positions 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca400d94d82781e5da9ac461bd06399a
https://pubmed.ncbi.nlm.nih.gov/31769463
https://pubmed.ncbi.nlm.nih.gov/31769463
Autor:
Bruce K. Cassels, Gabriela Díaz-Véliz, Vicente Castro-Castillo, Alejandro Hernández, Luis Valladares, Patricio Sáez-Briones, Rafael Barra
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. Nevertheless, the roles of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b2abea0fac12d06e2c61ff6d67c5fc
https://www.frontiersin.org/article/10.3389/fphar.2019.00157/full
https://www.frontiersin.org/article/10.3389/fphar.2019.00157/full