Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vicencia Sales"'
Autor:
Marina Burgos, Charlles Heldan de Moura Castro, Carolina Batista, Niels Olsen Saraiva Câmara, Angela Castoldi, Jessica L. O. Branquinho, Vicencia Sales, João Bosco Pesquero, Elton Dias da Silva, Valeria Oliveira, Marcelo A. Mori, Thais Oliveira Gonçalves-Zillo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The kinin B 1 receptor (B 1 R) plays a role in inflammatory and metabolic processes. B 1 R deletion (B 1 −/− ) protects mice from diet-induced obesity and improves insulin and leptin sensitivity. In contrast, genetic reconstitution of B 1 R exclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da65e195bd9445f179d192df35cae95
https://doi.org/10.2337/db18-1150
https://doi.org/10.2337/db18-1150
Autor:
Suzuka Sanechika, Joji Kusuyama, Elvira Isganaitis, Mary-Elizabeth Patti, Jeremy Chimene-Weiss, Vicencia Sales, Jessica Desmond, Robert E. Gerszten, Lei Wu, Chisayo Kozuka, Jun Qi, Soravis Osataphan, Christopher M. Mulla, Yixing Yuchi, Xu Shi, Laurie J. Goodyear
SummaryEpigenetic regulation is an important factor in glucose metabolism, but underlying mechanisms remain largely unknown. Here we demonstrated that bromodomain-containing proteins (Brds), transcriptional regulators binding to acetylated histone, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b497df4a8e65652dfa496ca364fc626e
Autor:
Antonio H. Martins, José Eduardo Krieger, Dulce Elena Casarini, Nawal M. Boukli, João Bosco Pesquero, Claudiana Lameu, P.C.M. Martins, Hellio Danny Nóbrega de Souza, Isis C. Nascimento, Rafael Dariolli, Vicencia Sales, Henning Ulrich, Talita Glaser, Janaina Maria Alves, Vinicius Bassaneze
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The bioactive peptide bradykinin obtained from cleavage of precursor kininogens activates the kinin-B2 receptor functioning in induction of inflammation and vasodilatation. In addition, bradykinin participates in kidney and cardiovascular development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833bdf61158f088e6426f422ffd23dc1
https://pubmed.ncbi.nlm.nih.gov/30338498
https://pubmed.ncbi.nlm.nih.gov/30338498
Autor:
Soravis, Osataphan, Chiara, Macchi, Garima, Singhal, Jeremy, Chimene-Weiss, Vicencia, Sales, Chisayo, Kozuka, Jonathan M, Dreyfuss, Hui, Pan, Yanin, Tangcharoenpaisan, Jordan, Morningstar, Robert, Gerszten, Mary-Elizabeth, Patti
Publikováno v:
JCI insight. 4(5)
Pharmacologic inhibition of the renal sodium/glucose cotransporter-2 induces glycosuria and reduces glycemia. Given that SGLT2 inhibitors (SGLT2i) reduce mortality and cardiovascular risk in type 2 diabetes, improved understanding of molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24fdb42604d7ca44e45e4c31e9292453
https://pubmed.ncbi.nlm.nih.gov/30843877
https://pubmed.ncbi.nlm.nih.gov/30843877
Autor:
Chiara Macchi, Yanin Tangjaroenpaisan, Vicencia Sales, Robert Gerszten, Jordan Morningstar, Soravis Osataphan, Jeremy I. Chimene-Weiss, Mary E. Patti, Chisayo Kozuka
Publikováno v:
Diabetes. 67
Given the impact of SGLT2 inhibitors to reduce overall mortality and CV risk in T2D, improved understanding of cellular and transcriptional mechanisms responsible for metabolic effects is required. We fed C57BL/6J mice a 60% high fat diet (HFD) for 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3bb36c0c529ae105ffb9c1f7658f5ca
https://doi.org/10.2337/db18-1836-p
https://doi.org/10.2337/db18-1836-p
Autor:
Nicholas W. Griffin, Huijuan Ma, Vicencia Sales, Yusuke Adachi, Tucker J Matthews, Wim Kulik, Jeffrey I. Gordon, Mary-Elizabeth Patti, Elvira Isganaitis, Sathish Subramanian, Michael Chen, Walt Gall, Ashley R. Wolf, Aparna Sharma, David E. Cohen
Publikováno v:
Endocrinology, 158(8), 2441-2452. The Endocrine Society
Prenatal undernutrition and low birth weight are associated with risk of type 2 diabetes and obesity. Prenatal caloric restriction results in low birth weight, glucose intolerance, obesity, and reduced plasma bile acids (BAs) in offspring mice. Becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bbaadf771a5de64a0712306bc6bbb9
https://europepmc.org/articles/PMC5551557/
https://europepmc.org/articles/PMC5551557/
Publikováno v:
Cell metabolism. 25(3)
Both human and animal studies indicate that environmental exposures experienced during early life can robustly influence risk for adult disease. Moreover, environmental exposures experienced by parents during either intrauterine or postnatal life can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62e6189b938ea41589827a4d04f4c7a
https://pubmed.ncbi.nlm.nih.gov/28273478
https://pubmed.ncbi.nlm.nih.gov/28273478
Autor:
Connor Fitzpatrick, Walter Gall, Michael Chen, Steven M. Watkins, Wen Kong, Elvira Isganaitis, Deborah Lee, Kyung Ju Lee, Cianna Leatherwood, Jennifer DeCoste-Lopez, Mary-Elizabeth Patti, Aristides Lytras, Huijuan Ma, Vicencia Sales, Melissa Woo
Publikováno v:
Diabetes
Maternal obesity and gestational diabetes mellitus (GDM) are associated with obesity and diabetes risk in offspring. We tested whether maternal insulin resistance, which frequently coexists with GDM and obesity, could independently contribute to dysr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e2ed4510df72a5ab79acbb01c102c1
http://europepmc.org/articles/PMC3900545
http://europepmc.org/articles/PMC3900545
Autor:
Thais Oliveira Gonçalves-Zillo, João Bosco Pesquero, José Daniel Lopes, Carla Cristina Squaiella-Baptistão, Suzana M. Oliveira, Ieda Maria Longo-Maugéri, Livia Souza Pugliese, Vicencia Sales, Marcelo A. Mori, Ana Carolina Monteiro
Publikováno v:
Journal of Clinical Periodontology. 40:653-660
AIM The pathophysiology of periodontal diseases involves aspects of immunity and bone remodelling. Considering the role of the kinin B1 receptor (Bdkrb1) in inflammation and healing, the purpose of this study was to evaluate the contribution of Bdkrb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4436b197eac31299f9151c5186ba06e
https://doi.org/10.1111/jcpe.12097
https://doi.org/10.1111/jcpe.12097
Autor:
Eduardo R. Ropelle, Mario J.A. Saad, Vicencia Sales, Lila Missae Oyama, João Bosco Pesquero, Ronaldo C. Araujo, Raphael Gomes Fonseca, Silvia Saiuli Iuki Ihara, Carlos Castilho Barros
Publikováno v:
Journal of Molecular Medicine. 91:851-860
Kinins B1 and B2 receptors (B1R and B2R) are classically associated with inflammation, but our group has recently demonstrated new roles for B1R in metabolism using a knockout model (B1−/−). B1−/− mice display improvement on leptin and insuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45e3cc192811e718772b70f30cead700
https://doi.org/10.1007/s00109-013-1004-6
https://doi.org/10.1007/s00109-013-1004-6