Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Vibhakar C Kotak"'
Publikováno v:
Frontiers in Neural Circuits, Vol 9 (2015)
The representation of acoustic cues involves regions downstream from the auditory cortex (ACx). One such area, the perirhinal cortex (PRh), processes sensory signals containing mnemonic information. Therefore, our goal was to assess whether PRh recei
Externí odkaz:
https://doaj.org/article/2f85d3e41051432ba11ff01e8e1e6a08
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53438 (2013)
Inhibitory synapse dysfunction may contribute to many developmental brain disorders, including the secondary consequences of sensory deprivation. In fact, developmental hearing loss leads to a profound reduction in the strength of inhibitory postsyna
Externí odkaz:
https://doaj.org/article/c20929455f864b3a92d664e1d2b3e160
Publikováno v:
PLoS Biology, Vol 8, Iss 6, p e1000406 (2010)
Low-frequency sound localization depends on the neural computation of interaural time differences (ITD) and relies on neurons in the auditory brain stem that integrate synaptic inputs delivered by the ipsi- and contralateral auditory pathways that st
Externí odkaz:
https://doaj.org/article/7b5758b4213c476fba31abb5cfeb96ed
Autor:
Todd M. Mowery, Kristina B. Penikis, Stephen K. Young, Christopher E. Ferrer, Vibhakar C. Kotak, Dan H. Sanes
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2462-2468 (2017)
Summary: Corticostriatal circuits play a fundamental role in regulating many behaviors, and their dysfunction is associated with many neurological disorders. In contrast, sensory disorders, like hearing loss (HL), are commonly linked with processing
Externí odkaz:
https://doaj.org/article/0440da2678aa4f29bfcf9311dec7d251
Developmental expression of inhibitory synaptic long-term potentiation in the lateral superior olive
Autor:
Vibhakar C. Kotak, Dan H. Sanes
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Principal neurons of the lateral superior olivary nucleus (LSO) respond selectively to interaural level differences (ILD). To perform this computation, LSO neurons integrate excitatory synaptic drive from the ipsilateral ear with inhibitory synaptic
Externí odkaz:
https://doaj.org/article/3001e8167ac847779336485269198967
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Sensory systems influence one another during development and deprivation can lead to cross-modal plasticity. As auditory function begins before vision, we investigate the effect of manipulating visual experience during auditory cortex critical period
Publikováno v:
The Journal of Neuroscience. 35:6318-6325
Auditory learning is associated with an enhanced representation of acoustic cues in primary auditory cortex, and modulation of inhibitory strength is causally involved in learning. If this inhibitory plasticity is associated with task learning and im
Publikováno v:
Hippocampus. 27(12)
The perirhinal cortex (PRh) is a key region downstream of auditory cortex (ACx) that processes familiarity linked mnemonic signaling. In gerbils, ACx-driven EPSPs recorded in PRh neurons are largely shunted by GABAergic inhibition (Kotak et al., 2015
Publikováno v:
Journal of Neurophysiology. 112:802-813
Behavioral and neural findings demonstrate that animals can locate low-frequency sounds along the azimuth by detecting microsecond interaural time differences (ITDs). Information about ITDs is also available in the amplitude modulations (i.e., envelo
Publikováno v:
Journal of Neurophysiology. 110:999-1008
Sensory deprivation, such as developmental hearing loss, leads to an adjustment of synaptic and membrane properties throughout the central nervous system. These changes are thought to compensate for diminished sound-evoked activity. This model predic