Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections

Autor: Vibeke Børsholt Rudkjøbing, Trine Rolighed Thomsen, Yijuan Xu, Rachael Melton-Kreft, Azad Ahmed, Steffen Eickhardt, Thomas Bjarnsholt, Steen Seier Poulsen, Per Halkjær Nielsen, Joshua P. Earl, Garth D. Ehrlich, Claus Moser

Publikováno v: BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-13 (2016)

Abstract Background Necrotizing soft tissue infections (NSTIs) are a group of infections affecting all soft tissues. NSTI involves necrosis of the afflicted tissue and is potentially life threatening due to major and rapid destruction of tissue, whic

Externí odkaz: https://doaj.org/article/774cf5b201d64affa6c577785fa828c3

Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections

Autor: Claus Moser, Steffen Eickhardt, Azad Ahmed, Steen Seier Poulsen, Garth D. Ehrlich, Trine Rolighed Thomsen, Thomas Bjarnsholt, Per Halkjær Nielsen, Rachael Melton-Kreft, Vibeke Børsholt Rudkjøbing, Yijuan Xu, Joshua P. Earl

Publikováno v: BMC Infectious Diseases
Rudkjøbing, V B, Thomsen, T R, Xu, Y, Melton-Kreft, R, Ahmed, A, Eickhardt-Sørensen, S R, Bjarnsholt, T, Poulsen, S S, Nielsen, P H, P. Earl, J, Ehrlich, G & Moser, C 2016, ' Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections ', B M C Infectious Diseases, vol. 16, no. 1, 652 . https://doi.org/10.1186/s12879-016-1976-2
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-13 (2016)
Rudkjøbing, V B, Thomsen, T R, Xu, Y, Melton-Kreft, R, Ahmed, A, Eickhardt-Dalbøge, S R, Bjarnsholt, T, Poulsen, S S, Nielsen, P H, Earl, J P, Ehrlich, G D & Moser, C 2016, ' Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections ', B M C Infectious Diseases, vol. 16, 652 . https://doi.org/10.1186/s12879-016-1976-2

BACKGROUND: Necrotizing soft tissue infections (NSTIs) are a group of infections affecting all soft tissues. NSTI involves necrosis of the afflicted tissue and is potentially life threatening due to major and rapid destruction of tissue, which often

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9af4e8b0bb6a0abdba178836005136
https://doi.org/10.1186/s12879-016-1976-2

The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients

Autor: Vibeke Børsholt Rudkjøbing, Michael Givskov, Niels Høiby, Thomas Bjarnsholt, Trine Rolighed Thomsen, Morten Alhede, Ulla Johansen, Kasper Nørskov Kragh, Per Halkjær Nielsen

Publikováno v: Rudkjøbing, V B, Thomsen, T R, Alhede, M, Kragh, K N, Nielsen, P H, Johansen, U R, Givskov, M, Høiby, N & Bjarnsholt, T 2012, ' The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients ', F E M S Immunology and Medical Microbiology, vol. 65, no. 2, pp. 236-244 . https://doi.org/10.1111/j.1574-695X.2011.00925.x

Patients suffering from cystic fibrosis (CF) develop chronic lung infections because of highly viscous mucus, where bacteria can form biofilms. In this study, we investigated the microorganisms present in the lungs of end-stage and non-end-stage pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2720c01d43d6a5c6890c1ea2427b0b8
https://vbn.aau.dk/da/publications/b12367fe-575e-4375-b3ae-c149918f710c

Bacterial Diversity in Suspected Prosthetic Joint Infections:An Exploratory Study Using 16S rRNA Gene Analysis

Autor: Vibeke Børsholt Rudkjøbing, Jan Lorenzen, Per Halkjær Nielsen, Yijuan Xu, Trine Rolighed Thomsen, Ole Simonsen, Christian N. S. Pedersen, Henrik Carl Schønheyder

Publikováno v: Xu, Y, Rudkjøbing, V B, Simonsen, O, Pedersen, C, Lorenzen, J, Schønheyder, H C, Nielsen, P H & Thomsen, T R 2012, ' Bacterial Diversity in Suspected Prosthetic Joint Infections : An Exploratory Study Using 16S rRNA Gene Analysis ', F E M S Immunology and Medical Microbiology, vol. 65, no. 2, pp. 291-304 . https://doi.org/10.1111/j.1574-695X.2012.00949.x
Xu, Y, Rudkjøbing, V B, Simonsen, O, Pedersen, C, Lorenzen, J, Schønheyder, H C, Nielsen, P H & Thomsen, T R 2012, ' Bacterial diversity in suspected prosthetic joint infections:An exploratory study using 16S rRNA gene analysis ', F E M S Immunology and Medical Microbiology, vol. 65, no. 2, pp. 291-304 . https://doi.org/10.1111/j.1574-695X.2012.00949.x

Formation of biofilm is a prominent feature of prosthetic joint infections (PJIs) and constitutes a challenge to current sampling procedures and culture practices. Molecular techniques have a potential for improving diagnosis of biofilm-adapted, slow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b739298912bb69f0867b12d0321063
https://vbn.aau.dk/da/publications/a52c9307-5090-4b8c-9e28-02a126aeebc7

Identity and quantity of microorganisms in necrotising fasciitis determined by culture and molecular methods

Autor: Vibeke Børsholt Rudkjøbing, Trine Rolighed Thomsen, Per Halkjær Nielsen, Claus Moser

Publikováno v: Rudkjøbing, V B, Thomsen, T R, Nielsen, P H & Moser, C 2012, ' Identity and quantity of microorganisms in necrotising fasciitis determined by culture and molecular methods ', Danish Conference on Biotechnology and Molecular Biology, Vejle, Denmark, 24/05/2012-25/05/2012 .
Aalborg University

Necrotising fasciitis (NF), commonly known as flesh eating disease is a fast progressing, potentially lethal infection of the subcutaneous tissue/fascia. Treatment includes high doses of intravenous antibiotics and aggressive surgical debridement. Ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6171bfe8d6757abc32265e58802ad632
https://vbn.aau.dk/da/publications/65263ca7-ae8e-4e25-bc35-1dcabec414ef