Výsledky vyhledávání - "Vibe Gedsoe, Frokjaer"

Akademický článek

Genetic contributions to brain serotonin transporter levels in healthy adults

Autor: Silvia Elisabetta Portis Bruzzone, Arafat Nasser, Sagar Sanjay Aripaka, Marie Spies, Brice Ozenne, Peter Steen Jensen, Gitte Moos Knudsen, Vibe Gedsoe Frokjaer, Patrick MacDonald Fisher

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Abstract The serotonin transporter (5-HTT) critically shapes serotonin neurotransmission by regulating extracellular brain serotonin levels; it remains unclear to what extent 5-HTT levels in the human brain are genetically determined. Here we applied

Externí odkaz: https://doaj.org/article/9c8f47aa77904a78966d873e14043b05

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Akademický článek

Serotonin 4 receptor brain binding and oxytocin-promoted affective and social cognition in healthy women – A randomized controlled trial

Autor: Vibeke Høyrup Dam, Sidsel Høgsgaard Andersen, Sofie Trolle Pedersen, Dea Siggaard Stenbæk, Vibe Gedsoe Frokjaer

Publikováno v: Comprehensive Psychoneuroendocrinology, Vol 17, Iss , Pp 100224- (2024)

Background: Oxytocin is a neuropeptide known for its prosocial properties and role in social bonding, and intervention with intranasal oxytocin is posited to modulate affective and social cognition (i.e., hot cognition). Serotonin (5-HT) neurotransmi

Externí odkaz: https://doaj.org/article/5126808cc3a94e188c75d9ae58b43bba

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Akademický článek

Evaluating cognitive disturbances as treatment target and predictor of antidepressant action in major depressive disorder: A NeuroPharm study

Autor: Vibeke Høyrup Dam, Dea Siggaard Stenbæk, Kristin Köhler-Forsberg, Cheng Ip, Brice Ozenne, Barbara Jacquelyn Sahakian, Gitte Moos Knudsen, Martin Balslev Jørgensen, Vibe Gedsoe Frokjaer

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)

Abstract Cognitive disturbances in major depressive disorder (MDD) constitute a critical treatment target and hold promise as an early predictor of antidepressant treatment response; yet their clinical relevance is not fully established. Therefore, w

Externí odkaz: https://doaj.org/article/6b175c5514e4435589af750c3c07f3e9

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Akademický článek

Effects of an Oral Contraceptive on Dynamic Brain States and Network Modularity in a Serial Single-Subject Study

Autor: Kristian Høj Reveles Jensen, Drummond E-Wen McCulloch, Anders Stevnhoved Olsen, Silvia Elisabetta Portis Bruzzone, Søren Vinther Larsen, Patrick MacDonald Fisher, Vibe Gedsoe Frokjaer

Publikováno v: Frontiers in Neuroscience, Vol 16 (2022)

Hormonal contraceptive drugs are used by adolescent and adult women worldwide. Increasing evidence from human neuroimaging research indicates that oral contraceptives can alter regional functional brain connectivity and brain chemistry. However, ques

Externí odkaz: https://doaj.org/article/30a55a4be7dd4a01901a886d8915abc4

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Sexual function improves as depressive symptoms decrease during treatment with escitalopram: results of a naturalistic study of patients with major depressive disorder

Autor: Sophia Weber, Vibe Gedsoe Frokjaer, Sophia Armand, Julie Helmer Nielsen, Gitte Moos Knudsen, Martin Balslev Joergensen, Dea Siggaard Stenbaek, Annamaria Giraldi

Publikováno v: The Journal of Sexual Medicine. 20:161-169

BackgroundMajor depressive disorder (MDD) is closely associated with sexual dysfunction, which may worsen during treatment with selective serotonin reuptake inhibitors (SSRIs) due to the side effects of pharmacologic treatment.AimTo examine the assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63bf4cc50e816f0b5a7d26bca511e51c
https://doi.org/10.1093/jsxmed/qdac016

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Akademický článek

Predicting Treatment Outcome in Major Depressive Disorder Using Serotonin 4 Receptor PET Brain Imaging, Functional MRI, Cognitive-, EEG-Based, and Peripheral Biomarkers: A NeuroPharm Open Label Clinical Trial Protocol

Autor: Kristin Köhler-Forsberg, Anders Jorgensen, Vibeke H. Dam, Dea Siggaard Stenbæk, Patrick M. Fisher, Cheng-Teng Ip, Melanie Ganz, Henrik Enghusen Poulsen, Annamaria Giraldi, Brice Ozenne, Martin Balslev Jørgensen, Gitte Moos Knudsen, Vibe Gedsoe Frokjaer

Publikováno v: Frontiers in Psychiatry, Vol 11 (2020)

BackgroundBetween 30 and 50% of patients with major depressive disorder (MDD) do not respond sufficiently to antidepressant regimens. The conventional pharmacological treatments predominantly target serotonergic brain signaling but better tools to pr

Externí odkaz: https://doaj.org/article/21ee49e7001b4dcda75a1a33291516eb

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Akademický článek

No evidence for a role of the serotonin 4 receptor in five-factor personality traits: A positron emission tomography brain study.

Autor: Dea Siggaard Stenbæk, Vibeke Høyrup Dam, Patrick MacDonald Fisher, Nanna Hansen, Liv Vadskjær Hjordt, Vibe Gedsoe Frokjaer

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184403 (2017)

Serotonin (5-HT) brain architecture appears to be implicated in normal personality traits as supported by genetic associations and studies using molecular brain imaging. However, so far, no studies have addressed potential contributions to variation

Externí odkaz: https://doaj.org/article/25207aa0b5a643dfa013fa31ac42cf41

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Publikováno v: Köhler-Forsberg, K, Jorgensen, A, Dam, V H, Stenbæk, D S, Fisher, P M, Ip, C T, Ganz, M, Poulsen, H E, Giraldi, A, Ozenne, B, Jørgensen, M B, Knudsen, G M & Frokjaer, V G 2020, ' Predicting Treatment Outcome in Major Depressive Disorder Using Serotonin 4 Receptor PET Brain Imaging, Functional MRI, Cognitive-, EEG-Based, and Peripheral Biomarkers : A NeuroPharm Open Label Clinical Trial Protocol ', Frontiers in Psychiatry, vol. 11, 641 . https://doi.org/10.3389/fpsyt.2020.00641
Frontiers in Psychiatry, Vol 11 (2020)
Frontiers in Psychiatry

Background: Between 30 and 50% of patients with major depressive disorder (MDD) do not respond sufficiently to antidepressant regimens. The conventional pharmacological treatments predominantly target serotonergic brain signaling but better tools to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b42c5351cb7a770720dec148edc4f6
https://curis.ku.dk/ws/files/247155025/Predicting_Treatment_Outcome_in_Major_Depressive_Disorder_Using_Serotonin_4_Receptor_PET_Brain_Imaging_Functional_MRI_Cognitive_EEG_Based_and_Peripheral_Biomarkers.pdf

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Fluctuations in [¹¹C]SB207145 PET binding associated with change in threat-related amygdala reactivity in humans

Autor: Patrick MacDonald, Fisher, Mette Ewers, Haahr, Christian Gaden, Jensen, Vibe Gedsoe, Frokjaer, Hartwig Roman, Siebner, Gitte Moos, Knudsen

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40(6)

Serotonin critically affects the neural processing of emotionally salient stimuli, including indices of threat; however, how alterations in serotonin signaling contribute to changes in brain function is not well understood. Recently, we showed in a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1934c4b1297f9f2b72ff367802baa3c8
https://pubmed.ncbi.nlm.nih.gov/25560201

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