Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Viacheslav Malikov"'
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
HIV infection results in elevated beta-amyloid (Aβ) levels in the brain, but the underlying mechanisms are unclear. Here, the authors show that amyloid precursor protein inhibits virion production and that HIV Gag, counteracting this antiviral funct
Externí odkaz:
https://doaj.org/article/4bb6852761304008b18756776bcceede
Autor:
Viacheslav Malikov, Mojgan H. Naghavi
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2792-2799 (2017)
Although microtubule motors mediate intracellular virus transport, the underlying interactions and control mechanisms remain poorly defined. This is particularly true for HIV-1 cores, which undergo complex, interconnected processes of cytosolic trans
Externí odkaz:
https://doaj.org/article/5b4f01a23de04e23aa3149d971868744
Autor:
Pei-Tzu Huang, Brady James Summers, Chaoyi Xu, Juan R. Perilla, Viacheslav Malikov, Mojgan H. Naghavi, Yong Xiong
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2373-2385.e7 (2019)
Summary: HIV-1 uses the microtubule network to traffic the viral capsid core toward the nucleus. Viral nuclear trafficking and infectivity require the kinesin-1 adaptor protein FEZ1. Here, we demonstrate that FEZ1 directly interacts with the HIV-1 ca
Externí odkaz:
https://doaj.org/article/c62658cee8ae4004b34683a4aec40077
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the Methods section ‘Viruses and drugs’. The timing for drug treatment of CHME3 4 × 4 or 293T cells with γ-secretase inhibitor or BACE1 inhibitor was incorrectly given as ‘1 day prior
Externí odkaz:
https://doaj.org/article/6c026654b4044287a63e0ddea5d16de2
Autor:
Viacheslav Malikov, Mojgan H. Naghavi
Publikováno v:
Journal of Virology.
As a hub protein, fasciculation and elongation factor zeta 1 (FEZ1) interacts with a range of other proteins involved in various biological processes, acting as an adaptor for the microtubule (MT) motor kinesin-1 to mediate outward transport of intra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::397f6fa46d2a561d2b779f7ac6bbaee9
https://doi.org/10.1128/jvi.00499-23
https://doi.org/10.1128/jvi.00499-23
Autor:
M Keegan Delaney, Feng Gu, Mojgan H. Naghavi, Eveline Santos da Silva, Shanmugapriya Shanmugapriya, Viacheslav Malikov
Publikováno v:
EMBO J
While the microtubule end-binding protein, EB1 facilitates early stages of HIV-1 infection, how it does so remains unclear. Here, we show that beyond its effects on microtubule acetylation, EB1 also indirectly contributes to infection by delivering t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b511e35913e9d43607aa776063321bc9
https://pubmed.ncbi.nlm.nih.gov/32896909
https://pubmed.ncbi.nlm.nih.gov/32896909
Publikováno v:
Cell Reports. 38:110396
Fasciculation and elongation protein zeta-1 (FEZ1) is a multifunctional kinesin adaptor involved in processes ranging from neurodegeneration to retrovirus and polyomavirus infection. Here, we show that, although modulating FEZ1 expression also impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ee11b7c1a46d6851049d89f3d562b6
https://doi.org/10.1016/j.celrep.2022.110396
https://doi.org/10.1016/j.celrep.2022.110396
Autor:
Scott G. Morham, Vladimir Jovasevic, Derek Walsh, Yosef Sabo, Qingqing Chai, Viacheslav Malikov, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
While beta-amyloid (Aβ), a classic hallmark of Alzheimer’s disease (AD) and dementia, has long been known to be elevated in the human immunodeficiency virus type 1 (HIV-1)-infected brain, why and how Aβ is produced, along with its contribution to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009ff952315852543dc93e872b415f97
http://link.springer.com/article/10.1038/s41467-017-01795-8
http://link.springer.com/article/10.1038/s41467-017-01795-8
Autor:
Chaoyi Xu, Mojgan H. Naghavi, Juan R. Perilla, Yong Xiong, Pei-Tzu Huang, Brady James Summers, Viacheslav Malikov
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2373-2385.e7 (2019)
Cell Reports
Cell Reports
Summary: HIV-1 uses the microtubule network to traffic the viral capsid core toward the nucleus. Viral nuclear trafficking and infectivity require the kinesin-1 adaptor protein FEZ1. Here, we demonstrate that FEZ1 directly interacts with the HIV-1 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efad05bbfabcea5080e958e2b189cc3
https://europepmc.org/articles/PMC6736649/
https://europepmc.org/articles/PMC6736649/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(33)
Diaphanous (Dia)-related formins (DRFs) coordinate cytoskeletal remodeling by controlling actin nucleation and microtubule (MT) stabilization to facilitate processes such as cell polarization and migration; yet the full extent of their activities rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed806566a3d57cd3f1f290bff845961
https://pubmed.ncbi.nlm.nih.gov/28760985
https://pubmed.ncbi.nlm.nih.gov/28760985