Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Vi Pham"'
Autor:
Jonathon Telianidis, Andrew Hunter, Robert Widdop, Barbara Kemp-Harper, Vi Pham, Claudia McCarthy, Siew Yeen Chai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Stroke is a leading cause of mortality and morbidity with a paucity of effective pharmacological treatments. We have previously identified insulin-regulated aminopeptidase (IRAP) as a potential target for the development of a new class of dr
Externí odkaz:
https://doaj.org/article/6c6112b0a1984bf38f7ea640e5591451
Autor:
Wessel A. C. Burger, Vi Pham, Ziva Vuckovic, Alexander S. Powers, Jesse I. Mobbs, Yianni Laloudakis, Alisa Glukhova, Denise Wootten, Andrew B. Tobin, Patrick M. Sexton, Steven M. Paul, Christian C. Felder, Radostin Danev, Ron O. Dror, Arthur Christopoulos, Celine Valant, David M. Thal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The M4 muscarinic acetylcholine receptor (M4 mAChR) has emerged as a drug target of high therapeutic interest due to its expression in regions of the brain involved in the regulation of psychosis, cognition, and addiction. The mAChR agonist,
Externí odkaz:
https://doaj.org/article/7484d1906038449ebf83ab0a1980953a
Autor:
Ahmed Haider, Xiaoyun Deng, Olivia Mastromihalis, Stefanie K. Pfister, Troels E. Jeppesen, Zhiwei Xiao, Vi Pham, Shaofa Sun, Jian Rong, Chunyu Zhao, Jiahui Chen, Yinlong Li, Theresa R. Connors, April T. Davenport, James B. Daunais, Vahid Hosseini, Wenqing Ran, Arthur Christopoulos, Lu Wang, Celine Valant, Steven H. Liang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 213-226 (2023)
There is an accumulating body of evidence implicating the muscarinic acetylcholine receptor 4 (M4) in schizophrenia and dementia with Lewy bodies, however, a clinically validated M4 positron emission tomography (PET) radioligand is currently lacking.
Externí odkaz:
https://doaj.org/article/23c849f24d484180a951dacc1844f3f8
Autor:
Ziva Vuckovic, Jinan Wang, Vi Pham, Jesse I Mobbs, Matthew J Belousoff, Apurba Bhattarai, Wessel AC Burger, Geoff Thompson, Mahmuda Yeasmin, Vindhya Nawaratne, Katie Leach, Emma T van der Westhuizen, Elham Khajehali, Yi-Lynn Liang, Alisa Glukhova, Denise Wootten, Craig W Lindsley, Andrew Tobin, Patrick Sexton, Radostin Danev, Celine Valant, Yinglong Miao, Arthur Christopoulos, David M Thal
Publikováno v:
eLife, Vol 12 (2023)
Allosteric modulation of G protein-coupled receptors (GPCRs) is a major paradigm in drug discovery. Despite decades of research, a molecular-level understanding of the general principles that govern the myriad pharmacological effects exerted by GPCR
Externí odkaz:
https://doaj.org/article/7f71dbdee2334fc988c8a96b377f0938
Autor:
Ryan P. Cheng, Puneet Dang, Alemji A. Taku, Yoon Ji Moon, Vi Pham, Xiaohe Sun, Ethan Zhao, Jonathan A. Raper
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract Background Olfactory Sensory Neuron (OSN) axons project from the zebrafish olfactory epithelium to reproducible intermediate target locations in the olfactory bulb called protoglomeruli at early stages in development. Two classes of OSNs exp
Externí odkaz:
https://doaj.org/article/d0b9b667e0994453a23e90123b541f3c
Autor:
Ryan P. Cheng, Puneet Dang, Alemji A. Taku, Yoon Ji Moon, Vi Pham, Xiaohe Sun, Ethan Zhao, Jonathan A. Raper
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/dc3ebe05ac1e4cd49e9fecac4a10ba89
Autor:
Jesse J. DiCello, Simona E. Carbone, Ayame Saito, Pradeep Rajasekhar, Rhian A. Ceredig, Vi Pham, Celine Valant, Arthur Christopoulos, Nicholas A. Veldhuis, Meritxell Canals, Dominique Massotte, Daniel P. Poole
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 465-483 (2020)
Background & Aims: Functional interactions between the mu opioid receptor (MOR) and delta opioid receptor (DOR) represent a potential target for novel analgesics and may drive the effects of the clinically approved drug eluxadoline for the treatment
Externí odkaz:
https://doaj.org/article/8f8f779f1b2f4f4d943c4c44b64c0667
Autor:
Nguyen Bao Danh, Le Thi Thanh Van, Doan Thi Thu Hang, Le Thai Hoang, Tuong Luong Quang, Vi Pham Thi Thuy, Tran Thi Van Trinh, Le Trung Duc, Thanh Tran
Publikováno v:
E3S Web of Conferences, Vol 405, p 01003 (2023)
Shrimp farming has emerged as a multi-billion-dollar industry in our country, creating numerous economic benefits. However, this sector has several negative environmental impacts. Recent studies on the utilization of microalgae for wastewater treatme
Externí odkaz:
https://doaj.org/article/7f5bdbf8ce644c4d860c07f964d19cd1
Autor:
Ly Ngoc Yen Nhi* , Nguyen Thi Tuong Vi, Pham Yen Linh, Pham Hoang Bao Vy, Pham Nguyen Ngoc Thu
Publikováno v:
Tạp chí Khoa học, Vol 53, Iss Special Issue 2, Pp 200-210 (2024)
Today, academic support services have become increasingly important to universities because they can help students develop knowledge and skills to more easily achieve success during university studies, thereby contributing to developing the reputati
Externí odkaz:
https://doaj.org/article/002547344c20441a825ee10d9d76c20c
Autor:
Hoang, Huong Thi Xuan, Le, Quyen Thi Le, Do, Vi Pham Nhat, Nguyen, Anh Thi Hong, Bui, Quang Vinh
Publikováno v:
PLoS ONE; 9/20/2024, Vol. 19 Issue 9, p1-12, 12p