Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Vi Luan Ha"'
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100090- (2020)
Summary: Single cell RNA sequencing of human thymic cells is dependent on isolation of highly pure and viable cell populations. This protocol describes the isolation of CD34+ progenitor and more differentiated CD34– fractions from post-natal thymic
Externí odkaz:
https://doaj.org/article/f1abd48e71fa4d71993df58337025ece
Autor:
Brigitte N. Gomperts, Lee Goodglick, Steven M. Dubinett, William D. Wallace, Tonya C. Walser, Ignacio I. Wistuba, Luisa M. Solis, Avrum Spira, Marc E. Lenburg, Adam C. Gower, David Chia, Erin L. Maresh, Mohammad Alavi, Steve Horvath, Ahmed E. Hegab, Vi Luan Ha, Jennifer L. Gilbert, Derek W. Nickerson, Vei Mah, Aik T. Ooi
Smoking is the most important known risk factor for the development of lung cancer. Tobacco exposure results in chronic inflammation, tissue injury, and repair. A recent hypothesis argues for a stem/progenitor cell involved in airway epithelial repai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e27d09eee813b48a6b93a1a2955e956
https://doi.org/10.1158/0008-5472.c.6500286
https://doi.org/10.1158/0008-5472.c.6500286
Autor:
Brigitte N. Gomperts, Lee Goodglick, Steven M. Dubinett, William D. Wallace, Tonya C. Walser, Ignacio I. Wistuba, Luisa M. Solis, Avrum Spira, Marc E. Lenburg, Adam C. Gower, David Chia, Erin L. Maresh, Mohammad Alavi, Steve Horvath, Ahmed E. Hegab, Vi Luan Ha, Jennifer L. Gilbert, Derek W. Nickerson, Vei Mah, Aik T. Ooi
Supplementary Methods, Tables 1-4, Figures 1-6 from Presence of a Putative Tumor-Initiating Progenitor Cell Population Predicts Poor Prognosis in Smokers with Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b4b45cd4e45b59eaf98a2904857b2c
https://doi.org/10.1158/0008-5472.22382682.v1
https://doi.org/10.1158/0008-5472.22382682.v1
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100090-(2020)
STAR Protocols
STAR Protocols
Summary Single cell RNA sequencing of human thymic cells is dependent on isolation of highly pure and viable cell populations. This protocol describes the isolation of CD34+ progenitor and more differentiated CD34– fractions from post-natal thymic
Akademický článek
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Autor:
Vi Luan Ha, Grigoriy Gogoshin, Andrei S. Rodin, Annie Luong, Sergio Branciamore, Jeong Eun Park, Virginia Camacho, Fan Li, Justin Le, Sweta B. Patel, Yong-Hwee Eddie Loh, Chintan Parekh, Robert S. Welner
Publikováno v:
Immunity
Summary The challenges in recapitulating in vivo human T cell development in laboratory models have posed a barrier to understanding human thymopoiesis. Here, we used single-cell RNA sequencing (sRNA-seq) to interrogate the rare CD34+ progenitor and
Autor:
Justin Le, Sweta Patel, Vi Luan Ha, Chintan Parekh, Robert S. Welner, Virginia Camacho, Fan Li
Publikováno v:
Blood. 134:1183-1183
The initial stages of thymopoiesis are characterized by the induction of T-lineage genes (specification) and the repression of alternative lineage genes (commitment). Multilineage (Thy1 and Thy2) and committed (Thy3) populations representing successi
Autor:
Daphne O. Darmawan, Ahmed E. Hegab, Bharti Bisht, Yeon Sun Kim, Jennifer L. Gilbert, Brigitte N. Gomperts, Yasser S. Attiga, Derek W. Nickerson, Manash K. Paul, Jackelyn A. Alva-Ornelas, Kelvin Xi Zhang, Vi Luan Ha, Aik Ooi
Publikováno v:
Stem cells and development, vol 23, iss 6
Both basal and submucosal gland (SMG) duct stem cells of the airway epithelium are capable of sphere formation in the in vitro sphere assay, although the efficiency at which this occurs is very low. We sought to improve this efficiency of sphere form
Publikováno v:
Respirology. 17:1101-1113
Background and objective: The heterotopic syngeneic tracheal transplant mouse model is an acute hypoxic-ischemic injury model that undergoes complete repair and regeneration. We hypothesized that the repair and regeneration process of the surface epi
Autor:
Ahmed E. Hegab, Bharti Bisht, Stephen P. Malkoski, Kelvin Xi Zhang, Derek W. Nickerson, Vi Luan Ha, Andy T. Chon, Aik Ooi, Brigitte N. Gomperts, Matteo Pellegrini, Daphne O. Darmawan, Jennifer L. Gilbert
Publikováno v:
Stem Cells. 29:1283-1293
The airway epithelium is in direct contact with the environment and therefore constantly at risk for injury. Basal cells (BCs) have been found to repair the surface epithelium (SE), but the contribution of other stem cell populations to airway epithe