Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vít Karafiát"'
Autor:
Magda Matoušková, Jiří Plachý, Dana Kučerová, Ľubomíra Pecnová, Markéta Reinišová, Josef Geryk, Vít Karafiát, Tomáš Hron, Jiří Hejnar
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012468 (2024)
Genetic editing of the germline using CRISPR/Cas9 technology has made it possible to alter livestock traits, including the creation of resistance to viral diseases. However, virus adaptability could present a major obstacle in this effort. Recently,
Externí odkaz:
https://doaj.org/article/67999101ee64415f8be86a564cc413ce
Autor:
Michal Dvořák, Roman Kodet, Zdena Zemanová, Dana Průková, Vít Karafiát, Jarmila Králová, Vladimír Pečenka, Petr Pajer
Supplementary Table 1 from Identification of Potential Human Oncogenes by Mapping the Common Viral Integration Sites in Avian Nephroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a926daa4099ee05cc93b3e23a5ffc9
https://doi.org/10.1158/0008-5472.22365129.v1
https://doi.org/10.1158/0008-5472.22365129.v1
Autor:
Michal Dvořák, Roman Kodet, Zdena Zemanová, Dana Průková, Vít Karafiát, Jarmila Králová, Vladimír Pečenka, Petr Pajer
Gene deregulation is a frequent cause of malignant transformation. Alteration of the gene structure and/or expression leading to cellular transformation and tumor growth can be experimentally achieved by insertion of the retroviral genome into the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fbc6d0fe6b589b7ce103609b07e4df
https://doi.org/10.1158/0008-5472.c.6494547
https://doi.org/10.1158/0008-5472.c.6494547
Autor:
Michal Dvořák, Petra Kašparová, Jiří Plachý, Jana Dudlová, Dana Pru̇ková, Vladimír Pec̆enka, Vít Karafiát, Petr Pajer
Supplementary Materials from Industasis, a Promotion of Tumor Formation by Nontumorigenic Stray Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf731a5ee4bed2b69a8ca49a16573f39
https://doi.org/10.1158/0008-5472.22377780
https://doi.org/10.1158/0008-5472.22377780
Publikováno v:
Journal of Virology. 91
Myeloblastosis-associated virus 2 (MAV-2) is a highly tumorigenic simple avian retrovirus. Chickens infected in ovo with MAV-2 develop tumors in the kidneys, lungs, and liver with a short latency, less than 8 weeks. Here we report the results of mole
Autor:
Jana Dudlova, Vladimír Pecenka, Jirí Plachy, Vít Karafiát, Dana Pruková, Michal Dvorak, Petr Pajer, Petra Kašparová
Publikováno v:
Cancer Research. 69:4605-4612
A tumor cell is formed when a critical amount of endogenous and/or exogenous tumorigenic stimuli is exceeded. We have shown that the transient presence of nontumorigenic stray cells in tissues of experimental animals that contain cells with a subcrit
Publikováno v:
Cellular and Molecular Life Sciences. 64:2975-2984
The c-myb proto-oncogene and its oncogenic derivative v−mybAMV encode transcriptional regulators engaged in the commitment of hematopoietic cells. While the c-Myb protein is important for the formation and differentiation of various progenitors, th
Autor:
Roman Kodet, Dana Průková, Vít Karafiát, Vladimír Pečenka, Zdena Zemanová, Petr Pajer, Michal Dvořák, Jarmila Králová
Publikováno v:
Cancer Research. 66:78-86
Gene deregulation is a frequent cause of malignant transformation. Alteration of the gene structure and/or expression leading to cellular transformation and tumor growth can be experimentally achieved by insertion of the retroviral genome into the ho
Publikováno v:
Oncogene. 22:665-673
The genes involved in the transformation of kidney blastema cells were searched for in avian nephroblastomas induced by the MAV2 retrovirus. The twist gene was identified as a common site of provirus integration in tumor cells. Twist was rearranged b
Publikováno v:
Blood Cells, Molecules, and Diseases. 27:437-445
The v-myb(AMV) oncogene transforms myelomonocytic cells in vitro and induces acute monoblastic leukemia in chickens. We analyzed the activity of the evolutionarily conserved PEST-like domain (P1 domain) for biochemical and biological activities of v-