Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients.

Autor: Ismail, Mohamed A.^1,2 mhmd_arby@yahoo.com, Vezzalini, Marzia³, Morsi, Hisham⁴, Abujaber, Ahmad², Al Sayab, Ali², Siveen, Kodappully², Yassin, Mohamed A.⁵, Monne, Maria⁶, Samara, Muthanna⁷, Cook, Richard¹, Sorio, Claudio³, Modjtahedi, Helmout¹, Al-Dewik, Nader I.^1,8,9 naldewik@hamad.qa

Publikováno v: Scientific Reports. 4/23/2021, Vol. 11 Issue 1, p1-12. 12p.

Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients

Autor: Ismail, Mohamed A., Vezzalini, Marzia, Morsi, Hisham, Abujaber, Ahmad, Al Sayab, Ali, Siveen, Kodappully, Yassin, Mohamed A., Monne, Maria, Samara, Muthanna, Cook, Richard, Sorio, Claudio, Modjtahedi, Helmout, Al-Dewik, Nader I.

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

Protein tyrosine phosphatase receptor gamma (PTPRG) is a member of the receptor-like family protein tyrosine phosphatases and acts as a tumor suppressor gene in different neoplasms. Recent studies reported the down-regulation of PTPRG expression leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3329c71f1a010d6886f01ee9ce730b

Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar

Autor: Ismail, Mohamed A., Samara, Muthanna, Al Sayab, Ali, Alsharshani, Mohamed, Yassin, Mohamed A., Varadharaj, Govindarajulu, Vezzalini, Marzia, Tomasello, Luisa, Monne, Maria, Morsi, Hisham, Qoronfleh, M. Walid, Zayed, Hatem, Cook, Richard, Sorio, Claudio, Modjtahedi, Helmout, Al‐Dewik, Nader I.

Publikováno v: Molecular Genetics and Genomic Medicine
Molecular Genetics & Genomic Medicine, Vol 8, Iss 10, Pp n/a-n/a (2020)
Molecular Genetics & Genomic Medicine

Background Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated in chronic myeloid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b4ac21a58d67ee61ed06fd8976841db
https://hdl.handle.net/10576/15406

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Additional file 1: of A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type Îł in chronic myeloid leukemia patients

Autor: Vezzalini, Marzia, Mafficini, Andrea, Tomasello, Luisa, Lorenzetto, Erika, Moratti, Elisabetta, Fiorini, Zeno, Holyoake, Tessa, Pellicano, Francesca, Krampera, Mauro, Tecchio, Cristina, Yassin, Mohamed, Al-Dewik, Nader, Ismail, Mohamed, Sayab, Ali Al, Monne, Maria, Sorio, Claudio

Supplementary material and methods.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2638ac76561758251ab7213f72bf1ced