Zobrazeno 1 - 10 of 252 pro vyhledávání: '"Veugelen S"'
1
Akademický článek
The signaling cascade of induction and maintenance of ES cell diapause.
Autor: Tarakhovsky A; Laboratory of Immune Cell Epigenetics and Signaling, The Rockefeller University., Zhang T; The Rockefeller University., Marina R; Harvard Medical School., Veugelen S; Max Planck Institute for Biology of Ageing., Mander P; GlaxoSmithKline., Prinjha R; Glaxo SmithKline., Schaefer A, Adelman K; Harvard Medical School.
Publikováno v: Research square [Res Sq] 2024 Sep 03. Date of Electronic Publication: 2024 Sep 03.
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3
Akademický článek
Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid β.
Autor: Sinha, Priyanka1 (AUTHOR) psinha4@mgh.harvard.edu, Turchyna, Yuliia1 (AUTHOR), Mitchell, Shane Patrick Clancy1 (AUTHOR), Sadek, Michael1 (AUTHOR), Armagan, Gokce1 (AUTHOR), Perrin, Florian1 (AUTHOR), Maesako, Masato1 (AUTHOR), Berezovska, Oksana1 (AUTHOR) psinha4@mgh.harvard.edu
Publikováno v: Cells (2073-4409). Oct2024, Vol. 13 Issue 19, p1600. 13p.
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4
Akademický článek
Melatonin Supplementation Alleviates Impaired Spatial Memory by Influencing Aβ 1-42 Metabolism via γ-Secretase in the icvAβ 1-42 Rat Model with Pinealectomy.
Autor: Georgieva, Irina1 (AUTHOR) igeorgieva@biomed.bas.bg, Tchekalarova, Jana2 (AUTHOR) janetchekalarova@gmail.com, Nenchovska, Zlatina2 (AUTHOR) zuzania@abv.bg, Kortenska, Lidia2 (AUTHOR) lkortenska@abv.bg, Tzoneva, Rumiana1 (AUTHOR) tzoneva@bio21.bas.bg
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10294. 12p.
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5
Qualitative changes in human ?-secretase underlie familial Alzheimer's disease
Autor: Szaruga M., Veugelen S., Benurwar M., Lismont S., Sepulveda-Falla D., Lleo A., Ryan N.S., Lashley T., Fox N.C., Murayama S., Gijsen H., De Strooper B., Chávez-Gutiérrez L.
Publikováno v: JOURNAL OF EXPERIMENTAL MEDICINE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Presenilin (PSEN) pathogenic mutations cause familial Alzheimer's disease (AD [FAD]) in an autosomal-dominant manner. The extent to which the healthy and diseased alleles influence each other to cause neurodegeneration remains unclear. In this study,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::a66587be8fe5b39e883e89069d8e5864
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10396
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6
Akademický článek
Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function.
Autor: Fabiano, Marietta1,2 (AUTHOR), Oikawa, Naoto1 (AUTHOR) naotooikawa@igm.hokudai.ac.jp, Kerksiek, Anja3 (AUTHOR), Furukawa, Jun-ichi4,5 (AUTHOR), Yagi, Hirokazu6,7 (AUTHOR), Kato, Koichi6,7,8 (AUTHOR), Schweizer, Ulrich2 (AUTHOR), Annaert, Wim9,10 (AUTHOR), Kang, Jongkyun11 (AUTHOR), Shen, Jie11,12 (AUTHOR), Lütjohann, Dieter3 (AUTHOR), Walter, Jochen1 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 10, p5417. 24p.
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7
Akademický článek
Autosomal Dominant Alzheimer's Disease Mutations in Human Microglia Are Not Sufficient to Trigger Amyloid Pathology in WT Mice but Might Affect Pathology in 5XFAD Mice.
Autor: Romero-Molina, Carmen1 (AUTHOR) carmen.romeromolina@mssm.edu, Neuner, Sarah M.1 (AUTHOR) neuner.sarah@gmail.com, Ryszawiec, Marcelina1 (AUTHOR) marcelina.ryszawiec@mssm.edu, Pébay, Alice2 (AUTHOR) apebay@unimelb.edu.au, Marcora, Edoardo1 (AUTHOR) edoardo.marcora@mssm.edu, Goate, Alison1 (AUTHOR) alison.goate@mssm.edu
Publikováno v: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2565. 18p.
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8
Akademický článek
Deletion of exons 9 and 10 of the Presenilin 1 gene in a patient with Early-onset Alzheimer Disease generates longer amyloid seeds.
Autor: Le Guennec K; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., Veugelen S; VIB - Center for Brain and Disease Research, University of Leuven, 3000 Leuven, Belgium; Center for Human Genetics, Leuven Research Institute for Neuroscience & Disease (LIND), University of Leuven, 3000 Leuven, Belgium., Quenez O; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., Szaruga M; VIB - Center for Brain and Disease Research, University of Leuven, 3000 Leuven, Belgium; Center for Human Genetics, Leuven Research Institute for Neuroscience & Disease (LIND), University of Leuven, 3000 Leuven, Belgium., Rousseau S; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., Nicolas G; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., Wallon D; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Neurology and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., Fluchere F; Department of Neurology and Movement Disorders, APHM, La Timone, Pôle de Neurosciences cliniques, Aix-Marseille Univ, Marseille, France., Frébourg T; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France., De Strooper B; VIB - Center for Brain and Disease Research, University of Leuven, 3000 Leuven, Belgium; Center for Human Genetics, Leuven Research Institute for Neuroscience & Disease (LIND), University of Leuven, 3000 Leuven, Belgium; Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK., Campion D; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France; Department of Research, Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France., Chávez-Gutiérrez L; VIB - Center for Brain and Disease Research, University of Leuven, 3000 Leuven, Belgium; Center for Human Genetics, Leuven Research Institute for Neuroscience & Disease (LIND), University of Leuven, 3000 Leuven, Belgium., Rovelet-Lecrux A; Normandie Univ, UNIROUEN, Inserm U1245, Rouen University Hospital, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, F 76000 Rouen, France. Electronic address: anne.roveletlecrux@univ-rouen.fr.
Publikováno v: Neurobiology of disease [Neurobiol Dis] 2017 Aug; Vol. 104, pp. 97-103. Date of Electronic Publication: 2017 Apr 28.
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9
Akademický článek
Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.
Autor: Szaruga M; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium., Munteanu B; Center of Applied Research in Biomedical Mass Spectrometry, Mannheim University of Applied Sciences, 68163 Mannheim, Germany., Lismont S; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium., Veugelen S; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium., Horré K; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium., Mercken M; Janssen Research & Development, Division of Janssen Pharmaceutica NV, 2340 Beerse, Belgium., Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Hirosawa Wako City, Saitama 351-0198, Japan., Ryan NS; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square, WC1N 3BG London, UK., De Vos T; Ghent University, Laboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, 9000 Ghent, Belgium; Center for Inflammation Research, VIB-UGent Technologiepark 927, 9052 Ghent, Belgium., Savvides SN; Ghent University, Laboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, 9000 Ghent, Belgium; Center for Inflammation Research, VIB-UGent Technologiepark 927, 9052 Ghent, Belgium., Gallardo R; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, University of Leuven, KU Leuven, Herestraat 49, 3000 Leuven, Belgium., Schymkowitz J; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, University of Leuven, KU Leuven, Herestraat 49, 3000 Leuven, Belgium., Rousseau F; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, University of Leuven, KU Leuven, Herestraat 49, 3000 Leuven, Belgium., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square, WC1N 3BG London, UK., Hopf C; Center of Applied Research in Biomedical Mass Spectrometry, Mannheim University of Applied Sciences, 68163 Mannheim, Germany., De Strooper B; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium; Dementia Research Institute UK, University College London, Queen Square, WC1N 3BG London, UK. Electronic address: Bart.DeStrooper@cme.vib-kuleuven.be., Chávez-Gutiérrez L; KU Leuven-VIB Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium; Department of Neurosciences, Leuven Institute for Neuroscience and Disease, KU Leuven, 3000 Leuven, Belgium. Electronic address: Lucia.ChavezGutierrez@cme.vib-kuleuven.be.
Publikováno v: Cell [Cell] 2017 Jul 27; Vol. 170 (3), pp. 443-456.e14.
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10
Akademický článek
Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins.
Autor: Veugelen S; University of Leuven, Leuven, Belgium; VIB Center for Brain and Disease, Leuven, Belgium., Dewilde M; University of Leuven, Leuven, Belgium; VIB Center for Brain and Disease, Leuven, Belgium., De Strooper B; University of Leuven, Leuven, Belgium; VIB Center for Brain and Disease, Leuven, Belgium; UCL Institute of Neurology, London, United Kingdom., Chávez-Gutiérrez L; University of Leuven, Leuven, Belgium; VIB Center for Brain and Disease, Leuven, Belgium. Electronic address: lucia.chavezgutierrez@cme.vib-kuleuven.be.
Publikováno v: Methods in enzymology [Methods Enzymol] 2017; Vol. 584, pp. 59-97. Date of Electronic Publication: 2016 Dec 12.
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