Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vesselina Semkova"'
Autor:
Lea Jessica Flitsch, Kathleen Börner, Christian Stüllein, Simon Ziegler, Vera Sonntag-Buck, Ellen Wiedtke, Vesselina Semkova, Si Wah Christina Au Yeung, Julia Schlee, Mohamad Hajo, Mona Mathews, Beatrice Stefanie Ludwig, Susanne Kossatz, Horst Kessler, Dirk Grimm, Oliver Brüstle
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Human brain cells generated by in vitro cell programming provide exciting prospects for disease modeling, drug discovery and cell therapy. These applications frequently require efficient and clinically compliant tools for genetic modificatio
Externí odkaz:
https://doaj.org/article/4875817cf7bc4d6497c93a0dff7c11d4
Autor:
Vesselina Semkova, Simone Haupt, Michaela Segschneider, Catherine Bell, Magnus Ingelman-Sundberg, Mohamad Hajo, Beatrice Weykopf, Pathma Muthukottiappan, Andreas Till, Oliver Brüstle
Publikováno v:
Cells, Vol 11, Iss 9, p 1388 (2022)
Understanding early nervous system stress response mechanisms is crucial for studying developmental neurotoxicity and devising neuroprotective treatments. We used hiPSC-derived long-term self-renewing neuroepithelial stem (lt-NES) cells differentiate
Externí odkaz:
https://doaj.org/article/de970b01338047e7b4aea76b7b0dec5d
Autor:
Denna Tabari, Catharina Scholl, Michael Steffens, Sandra Weickhardt, Fabian Elgner, Daniela Bender, Marie-Luise Herrlein, Catarina Sabino, Vesselina Semkova, Michael Peitz, Andreas Till, Oliver Brüstle, Eberhard Hildt, Julia Stingl
Publikováno v:
Viruses, Vol 12, Iss 11, p 1219 (2020)
Zika virus (ZIKV) is a mosquito-borne virus, which can cause brain abnormalities in newborns, including microcephaly. MicroRNAs (miRNAs) are small non-coding RNAs, which post- transcriptionally regulate gene expression. They are involved in various p
Externí odkaz:
https://doaj.org/article/66528ddcdc5c46a9904799fa6b162f6a
Autor:
Mona Mathews, Jannis Wißfeld, Lea Jessica Flitsch, Anahita Shahraz, Vesselina Semkova, Yannik Breitkreuz, Harald Neumann, Oliver Brüstle
Publikováno v:
Stem Cell Reviews and Reports. 19:455-474
Human microglia, as innate immune cells of the central nervous system (CNS), play a central role in the pathogenesis of a large number of neurological and psychiatric disorders. However, experimental access to primary human microglia for biomedical a
Autor:
Lea Jessica Flitsch, Christian Stüllein, Si Wah Christina Au Yeung, Oliver Brüstle, Simon Ziegler, Julia Schlee, Kathleen Börner, Mona Mathews, Vesselina Semkova, Vera Sonntag-Buck, Mohamad Hajo, Dirk Grimm
Human brain cells generated by in vitrocell programming provide exciting prospects for disease modeling, drug discovery and cell therapy. These applications frequently require efficient and clinically compliant tools for genetic modification of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e7a3f1f014990876732682a90b7275
https://doi.org/10.21203/rs.3.rs-861785/v1
https://doi.org/10.21203/rs.3.rs-861785/v1
Autor:
Lea Jessica, Flitsch, Kathleen, Börner, Christian, Stüllein, Simon, Ziegler, Vera, Sonntag-Buck, Ellen, Wiedtke, Vesselina, Semkova, Si Wah Christina, Au Yeung, Julia, Schlee, Mohamad, Hajo, Mona, Mathews, Beatrice Stefanie, Ludwig, Susanne, Kossatz, Horst, Kessler, Dirk, Grimm, Oliver, Brüstle
Publikováno v:
Scientific reports. 12(1)
Human brain cells generated by in vitro cell programming provide exciting prospects for disease modeling, drug discovery and cell therapy. These applications frequently require efficient and clinically compliant tools for genetic modification of the
Autor:
Heinz-Georg Jahnke, Mathilde Girard, Janine Obendorf, Simone Haupt, Diana Seidel, Andrea A. Robitzki, Marc Peschanski, Oliver Brüstle, Beate Englich, Vesselina Semkova
Publikováno v:
Biosensors and Bioelectronics. :277-286
In today's neurodevelopment and -disease research, human neural stem/progenitor cell-derived networks represent the sole accessible in vitro model possessing a primary phenotype. However, cultivation and moreover, differentiation as well as maturatio