Evolutionary Dynamics of a Lattice Dimer: a Toy Model for Stability vs. Affinity Trade-offs in Proteins

Autor: Loffredo, Emanuele, Vesconi, Elisabetta, Razban, Rostam, Peleg, Orit, Shakhnovich, Eugene, Cocco, Simona, Monasson, Rémi

Publikováno v: Journal of Physics A: Mathematical and Theoretical, Volume 56, Number 45, Published 13 October 2023 Random Landscapes and Dynamics in Evolution, Ecology and Beyond

Understanding how a stressor applied on a biological system shapes its evolution is key to achieving targeted evolutionary control. Here we present a toy model of two interacting lattice proteins to quantify the response to the selective pressure def

Externí odkaz: http://arxiv.org/abs/2303.12431