Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Vesa Hongisto"'
Autor:
Lisa Svartdal Normann, Mads Haugland Haugen, Vesa Hongisto, Miriam Ragle Aure, Suvi-Katri Leivonen, Vessela N Kristensen, Andliena Tahiri, Olav Engebraaten, Kristine Kleivi Sahlberg, Gunhild Mari Mælandsmo
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280507 (2023)
Human epidermal growth factor receptor 2-positive (HER2+) breast cancer is an aggressive subtype of this disease. Targeted treatment has improved outcome, but there is still a need for new therapeutic strategies as some patients respond poorly to tre
Externí odkaz:
https://doaj.org/article/a267b2c834e74bde9dda62efe4aa7af4
Autor:
Lisa Svartdal Normann, Miriam Ragle Aure, Suvi-Katri Leivonen, Mads Haugland Haugen, Vesa Hongisto, Vessela N. Kristensen, Gunhild Mari Mælandsmo, Kristine Kleivi Sahlberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract HER2-positive (HER2 +) breast cancer patients that do not respond to targeted treatment have a poor prognosis. The effects of targeted treatment on endogenous microRNA (miRNA) expression levels are unclear. We report that responsive HER2 + b
Externí odkaz:
https://doaj.org/article/0b40ee361d9441319955d2b6754721b1
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 249-253 (2014)
A large number of breast cancers are characterized by amplification and overexpression of the chromosome segment surrounding the HER2 (ERBB2) oncogene. As the HER2 amplicon at 17q12 contains multiple genes, we have systematically explored the role of
Externí odkaz:
https://doaj.org/article/712bc71cda264df7bdb4e4dc341ddded
Autor:
Caterina R. de Vera, Guillermo Díaz Crespín, Antonio Hernández Daranas, Sofia Montalvão Looga, Katja-Emilia Lillsunde, Päivi Tammela, Merja Perälä, Vesa Hongisto, Johannes Virtanen, Heiko Rischer, Christian D. Muller, Manuel Norte, José J. Fernández, María L. Souto
Publikováno v:
Marine Drugs, Vol 16, Iss 9, p 317 (2018)
The study of marine natural products for their bioactive potential has gained strength in recent years. Oceans harbor a vast variety of organisms that offer a biological and chemical diversity with metabolic abilities unrivalled in terrestrial system
Externí odkaz:
https://doaj.org/article/e3879d0157ae417ebc3158d1690128cd
Autor:
Vesa Hongisto, Sandra Jernström, Vidal Fey, John-Patrick Mpindi, Kristine Kleivi Sahlberg, Olli Kallioniemi, Merja Perälä
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77232 (2013)
The traditional method for studying cancer in vitro is to grow immortalized cancer cells in two-dimensional monolayers on plastic. However, many cellular features are impaired in these artificial conditions, and large changes in gene expression compa
Externí odkaz:
https://doaj.org/article/d33a1d35e37c4101a05b1d392918e049
Autor:
François Busquet, Jeanne Laperrouze, Katica Jankovic, Tamara Krsmanovic, Tomasz Ignasiak, Benedetta Leoni, Gordana Apic, Giovanni Asole, Roderic Guigó, Paolo Marangio, Emilio Palumbo, Silvia Perez-Lluch, Valentin Wucher, Anna Hendrika Vlot, Robert Anholt, Trudy Mackay, Beate I. Escher, Nico Grasse, Julia Huchthausen, Riccardo Massei, Thorsten Reemtsma, Stefan Scholz, Gerrit Schüürmann, Maria Bondesson, Peter Cherbas, Jonathan H. Freedman, Stephen Glaholt, Jessica Holsopple, Stephen C. Jacobson, Thomas Kaufman, Ellen Popodi, Joseph J. Shaw, Shannon Smoot, Jason M. Tennessen, Gary Churchill, Christina Cramer von Clausbruch, Thomas Dickmeis, Gaëlle Hayot, Giuseppina Pace, Ravindra Peravali, Carsten Weiss, Nadezda Cistjakova, Xin Liu, Andis Slaitas, James (Ben) Brown, Rafael Ayerbe, Joan Cabellos, Elena Cerro-Gálvez, María Diez-Ortiz, Verónica González, Rubén Martínez, Patricia Solórzano Vives, Rosemary Barnett, Thomas Lawson, Robert G. Lee, Elena Sostare, Mark Viant, Roland Grafström, Vesa Hongisto, Pekka Kohonen, Konrad Patyra, Pradeep Kumar Bhaskar, Marcial Garmendia-Cedillos, Ibraheem Farooq, Brian Oliver, Tom Pohida, Ghadi Salem, Daniel Jacobson, Elisabeth Andrews, Marianne Barnard, Aleksandra Čavoški, Anurag Chaturvedi, John K. Colbourne, David J.T. Epps, Laura Holden, Martin R. Jones, Xiaojing Li, Ferenc Müller, Agata Ormanin-Lewandowska, Luisa Orsini, Ruth Roberts, Ralf J.M. Weber, Jiarui Zhou, Mu-En Chung, Juan Carlos Gonzalez Sanchez, Gaurav D. Diwan, Gurdeep Singh, Uwe Strähle, Robert B. Russell, Dominique Batista, Susanna-Assunta Sansone, Philippe Rocca-Serra, David Du Pasquier, Gregory Lemkine, Barbara Robin-Duchesne, Andrew Tindall
The goal of PrecisionTox is to overcome conceptual barriers to replacing traditional mammalian chemical safety testing by accelerating the discovery of evolutionarily conserved toxicity pathways that are shared by descent among humans and more distan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876b7659dcbf87711644cfc5deccdefc
https://ora.ox.ac.uk/objects/uuid:bed21c1b-b26c-4b6d-aea0-dce1e848c810
https://ora.ox.ac.uk/objects/uuid:bed21c1b-b26c-4b6d-aea0-dce1e848c810
Autor:
Neeraj Shandilya, Christina Isaxon, Michael Persson, Daniel Persson, Marcel Moerman, Vesa Hongisto, Rico Ledwith, Angela Saccardo, Kirsty Meldrum, Martin J D Clift, Wouter Fransman
Publikováno v:
Annals of Work Exposures and Health. 67:i51-i51
Paint formulations are complex mixtures of both dissolved and particulate components, both organic and inorganic. Amorphous silica nanoparticles are included to make the paint layer dirt-repellent. Over entire life cycle of the paints containing such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2f20a75b1e7a827e62cb9e402207938
https://doi.org/10.1093/annweh/wxac087.123
https://doi.org/10.1093/annweh/wxac087.123
Autor:
Hanna L. Karlsson, Roland Grafström, Nina Jeliazkova, Penny Nymark, Vesa Hongisto, P. Kohonen
Publikováno v:
Toxicology Letters. 350:S9-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9e0ffd97d75cbad504da9fa046615b
https://doi.org/10.1016/s0378-4274(21)00255-1
https://doi.org/10.1016/s0378-4274(21)00255-1
Autor:
Chris T. Evelo, Friederike Ehrhart, Nina Jeliazkova, Penny Nymark, Haralambos Sarimveis, Pekka Kohonen, Georgia Tsiliki, Linda Rieswijk, Roland C. Grafström, Egon Willighagen, Vesa Hongisto
Publikováno v:
Toxicological Sciences, 162(1), 264-275. Oxford University Press
Toxicological Sciences
Toxicological Sciences
Increasing amounts of systems toxicology data, including omics results, are becoming publically available and accessible in databases. Data-driven and informatics-tool supported pipeline schemas for fitting such data into Adverse Outcome Pathway (AOP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b4224cffc99a3bdf3d8b3140b1e107
https://doi.org/10.1093/toxsci/kfx252
https://doi.org/10.1093/toxsci/kfx252
Autor:
Egon Willighagen, Vesa Hongisto, A. Beronius, Sabina Halappanavar, Roland Grafström, Marvin Martens, P. Kohonen, Penny Nymark
Publikováno v:
Toxicology Letters. 350:S38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c63f8ec84d03f30bebe7c9153e01203
https://doi.org/10.1016/s0378-4274(21)00335-0
https://doi.org/10.1016/s0378-4274(21)00335-0