Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Vesa‐Pekka Lehto"'
Autor:
Feng Zhou, Lujia Huang, Shiqin Li, Wenfang Yang, Fangmin Chen, Zhixiong Cai, Xiaolong Liu, Wujun Xu, Vesa‐Pekka Lehto, Ulrich Lächelt, Rongqin Huang, Yang Shi, Twan Lammers, Wei Tao, Zhi Ping Xu, Ernst Wagner, Zhiai Xu, Haijun Yu
Publikováno v:
Exploration, Vol 4, Iss 2, Pp n/a-n/a (2024)
Abstract mRNA therapeutics have emerged as powerful tools for cancer immunotherapy in accordance with their superiority in expressing all sequence‐known proteins in vivo. In particular, with a small dosage of delivered mRNA, antigen‐presenting ce
Externí odkaz:
https://doaj.org/article/34b48205a3e34f03bd0a9eda1f1da5e0
Autor:
Sanjeev Ranjan, Stef Bosch, Hannamari Lukkari, Johanna Schirmer, Niina Aaltonen, Heikki J. Nieminen, Vesa-Pekka Lehto, Arto Urtti, Tatu Lajunen, Kirsi Rilla
Publikováno v:
Nanomaterials, Vol 14, Iss 13, p 1089 (2024)
RNA-based therapeutics, including siRNA, have obtained recognition in recent years due to their potential to treat various chronic and rare diseases. However, there are still limitations to lipid-based drug delivery systems in the clinical use of RNA
Externí odkaz:
https://doaj.org/article/50ce1e20b7f44f92b42fd60f0f06139a
Autor:
Wujun Xu, Jarkko Leskinen, Teemu Sahlström, Emilia Happonen, Tanja Tarvainen, Vesa-Pekka Lehto
Publikováno v:
Photoacoustics, Vol 33, Iss , Pp 100552- (2023)
Many fluorophores, such as indocyanine green (ICG), have poor photostability and low photothermal efficiency hindering their wide application in photoacoustic (PA) tomography. In the present study, a supramolecular assembly approach was used to deve
Externí odkaz:
https://doaj.org/article/ff2f4a22599f439b89c23a8f8924230b
Autor:
Lizhi Liu, Dingyi Pan, Sheng Chen, Maria-Viola Martikainen, Anna Kårlund, Jing Ke, Herkko Pulkkinen, Hanna Ruhanen, Marjut Roponen, Reijo Käkelä, Wujun Xu, Jie Wang, Vesa-Pekka Lehto
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Surface modification of nanoparticles by cell membrane (CM) coating to improve their bio-interface properties often results in partial coating. Here the authors show that partial coating is an intermediate state due to the absorption of CM fragments
Externí odkaz:
https://doaj.org/article/ab51f24e902c4a3eb902d25937d65f18
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2507 (2023)
Mesoporous silicon nanoparticles (PSi NPs) are promising platforms of nanomedicine because of their good compatibility, high payload capacities of anticancer drugs, and easy chemical modification. Here, PSi surfaces were functionalized with bisphosph
Externí odkaz:
https://doaj.org/article/86121944aedd4e7ca3e76261da05eead
Autor:
Lizhi Liu, Xuan Bai, Maria-Viola Martikainen, Anna Kårlund, Marjut Roponen, Wujun Xu, Guoqing Hu, Ennio Tasciotti, Vesa-Pekka Lehto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating
Externí odkaz:
https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a8
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Lithium-ion batteries (LIBs) are the most preferred energy storage devices today for many high-performance applications. Recently, concerns about global warming and climate change have increased the need and requirements for LIBs used in electric veh
Externí odkaz:
https://doaj.org/article/b0b49e73d97441cbaff13be6f2856014
Autor:
Rinez Thapa, Subhasish Mondal, Joakim Riikonen, Jimi Rantanen, Simo Näkki, Tuomo Nissinen, Ale Närvänen, Vesa-Pekka Lehto
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009533 (2021)
Visceral leishmaniasis is a vector-borne protozoan infection that is fatal if untreated. There is no vaccination against the disease, and the current chemotherapeutic agents are ineffective due to increased resistance and severe side effects. Buparva
Externí odkaz:
https://doaj.org/article/6b20bb80379e45a8848183c6952ee115
Autor:
Somayeh Asadi, Sanzhar Korganbayev, Wujun Xu, Ana Katrina Mapanao, Valerio Voliani, Vesa-Pekka Lehto, Paola Saccomandi
Publikováno v:
Nanomaterials, Vol 12, Iss 6, p 945 (2022)
Many efforts have recently concentrated on constructing and developing nanoparticles (NPs) as promising thermal agent for optical hyperthermia and photothermal therapy. However, thermal energy transfer in biological tissue is a complex process involv
Externí odkaz:
https://doaj.org/article/23eb2c22896a466ca758a8436a0918cf
Autor:
Andrey Sviridov, Konstantin Tamarov, Ivan Fesenko, Wujun Xu, Valery Andreev, Victor Timoshenko, Vesa-Pekka Lehto
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
The presence of nanoparticles lowers the levels of ultrasound (US) intensity needed to achieve the therapeutic effect and improves the contrast between healthy and pathological tissues. Here, we evaluate the role of two main mechanisms that contribut
Externí odkaz:
https://doaj.org/article/bbcf939f33fa4ff980cf93f7004a11f2