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Inhibition of CXCR3-Mediated Chemotaxis by the Human Chemokine Receptor-like Protein CCX-CKR

Autor: Vinet, J., van Zwam, M., Dijkstra, I.M., Brouwer, N., van Weering, H.R.J., Meijer, M., Fokkens, M., Verzijl, D., Watts, A.O., Vischer, H.F., Smit, M.J., Leurs, R., Biber, K, Boddeke, H.W.G.M.

Publikováno v: British Journal of Pharmacology, 168(6), 1376-1387. Wiley-Blackwell
Vinet, J, van Zwam, M, Dijkstra, I M, Brouwer, N, van Weering, H R J, Meijer, M, Fokkens, M, Verzijl, D, Watts, A O, Vischer, H F, Smit, M J, Leurs, R, Biber, K & Boddeke, H W G M 2013, ' Inhibition of CXCR3-Mediated Chemotaxis by the Human Chemokine Receptor-like Protein CCX-CKR ', British Journal of Pharmacology, vol. 168, no. 6, pp. 1376-1387 . https://doi.org/10.1111/bph.12042

Background and Purpose Induction of cellular migration is the primary effect of chemokine receptor activation. However, several chemokine receptor-like proteins bind chemokines without subsequent induction of intracellular signalling and chemotaxis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2dc66d5d0871d37fe871b27931b8ec48
https://research.vu.nl/en/publications/a4934290-1210-4682-8114-849e9ec34dea

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Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3

Autor: Scholten, DJ, Canals, M, Wijtmans, M, de Munnik, S, Nguyen, P, Verzijl, D, de Esch, IJP, Vischer, HF, Smit, MJ, Leurs, R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::40de64370873bc629db7c642a3953e68
https://europepmc.org/articles/PMC3417417/

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Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR

Autor: Vinet, J., van Zwam, M., Dijkstra, I. M., Brouwer, N., van Weering, H. R. J., Watts, A., Meijer, M., Fokkens, M. R., Kannan, V., Verzijl, D., Vischer, H. F., Smit, M. J., Leurs, R., Biber, K., Boddeke, H. W. G. M.

Publikováno v: British Journal of Pharmacology, 168(6), 1375-1387. Wiley-Blackwell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::933774aa716d16d94f2443915bd171f8
https://pubmed.ncbi.nlm.nih.gov/23121557

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Pharmacological Characterisation of a Small-Molecule Agonist for the Chemokine Receptor CXCR3

Autor: Scholten, D.J., Canals, M., Wijtmans, M., de Munnik, S.M., Nguyen, D, Verzijl, D., de Esch, I.J.P., Vischer, H.F., Smit, M.J., Leurs, R.

Publikováno v: Scholten, D J, Canals, M, Wijtmans, M, de Munnik, S M, Nguyen, D, Verzijl, D, de Esch, I J P, Vischer, H F, Smit, M J & Leurs, R 2011, ' Pharmacological Characterisation of a Small-Molecule Agonist for the Chemokine Receptor CXCR3 ', British Journal of Pharmacology, vol. 166, no. 3, pp. 898-911 . https://doi.org/10.1111/j.1476-5381.2011.01648.x
British Journal of Pharmacology, 166(3), 898-911. Wiley-Blackwell

BACKGROUND AND PURPOSE The chemokine receptor CXCR3 is a GPCR found predominantly on activated T cells. CXCR3 is activated by three endogenous peptides; CXCL9, CXCL10 and CXCL11. Recently, a small-molecule agonist, VUF10661, has been reported in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c708200f43ee4b44be6886f8b98945d8
https://research.vu.nl/en/publications/476ae477-ce89-4f42-a72e-477605a6f7b8

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Quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors

Autor: Wijtmans, M., Verzijl, D., Bergmans, S., Lai, M., Bosch, L., Smit, M.J., de Esch, I.J.P., Leurs, R.

Publikováno v: Wijtmans, M, Verzijl, D, Bergmans, S, Lai, M, Bosch, L, Smit, M J, de Esch, I J P & Leurs, R 2011, ' Quaternary ammonium salts equipped with biphenyl-and polycycloaliphatic-anchors ', Bioorganic and Medicinal Chemistry, vol. 19, no. 11, pp. 3384-3393 . https://doi.org/10.1016/j.bmc.2011.04.035
Bioorganic and Medicinal Chemistry, 19(11), 3384-3393. Elsevier Limited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f5790a90d4b3d2c873f21a497f861b65
https://research.vumc.nl/en/publications/cf873e8d-4fdb-4ada-b1c8-67ba2b409838

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Sphingosine 1-Phosphate Receptor 1 and 3 Are Upregulated in Multiple Sclerosis Lesions

Autor: van Doorn, R.P., van Horssen, J., Verzijl, D., Witte, M.E., Ronken, E., Hof, B.V., Lakeman, K., Dijkstra, C.D., van der Valk, P., Reijerkerk, A., Alewijnse, A.E., Peters, S.L.M., de Vries, H.E.

Publikováno v: GLIA, 58(12), 1465-1476. John Wiley and Sons Inc.
van Doorn, R P, van Horssen, J, Verzijl, D, Witte, M E, Ronken, E, Hof, B V, Lakeman, K, Dijkstra, C D, van der Valk, P, Reijerkerk, A, Alewijnse, A E, Peters, S L M & de Vries, H E 2010, ' Sphingosine 1-Phosphate Receptor 1 and 3 Are Upregulated in Multiple Sclerosis Lesions ', GLIA, vol. 58, no. 12, pp. 1465-1476 . https://doi.org/10.1002/glia.21021

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d3dbd1fceb769034c34f55317b590d87
https://research.vumc.nl/en/publications/991b2a1f-ac1b-49f1-84f8-5b0d40602c4b

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