A deep learning model for segmentation of geographic atrophy to study its long-term natural history

Autor: Liefers, Bart, Colijn, Johanna M., González-Gonzalo, Cristina, Verzijden, Timo, Mitchell, Paul, Hoyng, Carel B., van Ginneken, Bram, Klaver, Caroline C. W., Sánchez, Clara I.

Publikováno v: Ophthalmology, Published February 14, 2020

Purpose: To develop and validate a deep learning model for automatic segmentation of geographic atrophy (GA) in color fundus images (CFIs) and its application to study growth rate of GA. Participants: 409 CFIs of 238 eyes with GA from the Rotterdam S

Externí odkaz: http://arxiv.org/abs/1908.05621

Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans.

Autor: Mauschitz, Matthias M., Verzijden, Timo, Schuster, Alexander K., Elbaz, Hisham, Pfeiffer, Norbert, Khawaja, Anthony, Luben, Robert N., Foster, Paul J., Rauscher, Franziska G., Wirkner, Kerstin, Kirsten, Toralf, Jonas, Jost B., Bikbov, Mukharram M., Hogg, Ruth, Peto, Tunde, Cougnard-Grégoire, Audrey, Bertelsen, Geir, Erke, Maja Gran, Topouzis, Fotis, Giannoulis, Dimitrios A.

Publikováno v: British Journal of Ophthalmology; Dec2023, Vol. 107 Issue 12, p1880-1886, 7p

The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium

Autor: Thee, Eric, Colijn, Johanna, Cougnard-Grégoire, Audrey, Meester-Smoor, Magda, Verzijden, Timo, Hoyng, Carel, Fauser, Sascha, Hense, Hans-Werner, Silva, Rufino, Creuzot-Garcher, Catherine, Ueffing, Marius, Delcourt, Cécile, den Hollander, Anneke, Klaver, Caroline C.W.

Publikováno v: Ophthalmology, 129(7), 752-764. Elsevier Inc.
Ophthalmology: Journal of The American Academy of Ophthalmology
Ophthalmology: Journal of The American Academy of Ophthalmology, 2022, 129 (7), pp.752-764. ⟨10.1016/j.ophtha.2022.02.026⟩

Purpose: Age-related maculopathy susceptibility 2 (ARMS2) is considered the most enigmatic of the genes for age-related macular degeneration (AMD). We investigated the phenotypic course and spectrum of AMD for the risk haplotype at the ARMS2 and high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e04133921c5d7fefa19bbde409f80f71
https://pure.eur.nl/en/publications/2c719e34-9879-4fbe-a364-a0ad5496af9f

Development of a Genotype Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

Autor: de Breuk, Anita, Acar, Ilhan E., Kersten, Eveline, Schijvenaars, Mascha M.V.A.P., Colijn, Johanna M., Haer-Wigman, Lonneke, Bakker, Bjorn, de Jong, Sarah, Meester-Smoor, Magda A., Verzijden, Timo, Missotten, Tom O.A.R., Monés, Jordi, Biarnés, Marc, Pauleikhoff, Daniel, Hense, Hans W., Silva, Rufino, Nunes, Sandrina, Melo, Joana B., Fauser, Sascha, Hoyng, Carel B., Ueffing, Marius, Coenen, Marieke J.H., Klaver, Caroline C.W., den Hollander, Anneke I., Ikram, A., Vingerling, Johannes

Publikováno v: Ophthalmology, 128(11), 1604-1617. Elsevier Inc.

Purpose: To develop a genotype assay to assess associations with common and rare age-related macular degeneration (AMD) risk variants, to calculate an overall genetic risk score (GRS), and to identify potential misdiagnoses with inherited macular dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::913b3810ee5b0a179309ec2ec41a6fe4
https://pure.eur.nl/en/publications/eb83d8d7-1917-41b8-a4e4-4b44080a8540

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