Enhanced aortic stiffness in adolescents with chronic disease is associated with decreased left ventricular global longitudinal strain.

Autor: Verpalen VA; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands.; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, the Netherlands., Ververs FA; Center for Translational Immunology, University Medical Center Utrecht, the Netherlands., Slieker M; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Nuboer R; Department of Pediatrics, Meander Medical Center Amersfoort, the Netherlands., Swart JF; Department of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., van der Ent CK; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Fejzic Z; Department of Pediatric Cardiology, Amalia Children's Hospital Radboud University Medical Center Nijmegen, the Netherlands., Westenberg JJM; Department of Radiology, Leiden University Medical Center, the Netherlands., Leiner T; Department of Radiology, Mayo Clinics, United States of America., Grotenhuis HB; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Schipper HS; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, the Netherlands.; Department of Pediatric Cardiology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, the Netherlands.

Publikováno v: International journal of cardiology. Heart & vasculature [Int J Cardiol Heart Vasc] 2024 Apr 26; Vol. 52, pp. 101385. Date of Electronic Publication: 2024 Apr 26 (Print Publication: 2024).

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells.

Autor: Ververs FA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Engelen SE; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Nuboer R; Department of Pediatrics, Meander Medical Center Amersfoort, Amersfoort, The Netherlands., Vastert B; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., van der Ent CK; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Van't Land B; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Center of Excellence Immunology, Danone Nutricia Research, Utrecht, The Netherlands., Garssen J; Center of Excellence Immunology, Danone Nutricia Research, Utrecht, The Netherlands.; Division Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Beta Faculty, Utrecht University, Utrecht, The Netherlands., Monaco C; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Boes M; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Schipper HS; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands. h.s.schipper-3@umcutrecht.nl.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. h.s.schipper-3@umcutrecht.nl.; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. h.s.schipper-3@umcutrecht.nl.

Publikováno v: Scientific reports [Sci Rep] 2021 Oct 11; Vol. 11 (1), pp. 20082. Date of Electronic Publication: 2021 Oct 11.

Recombination activity of human recombination-activating gene 2 (RAG2) mutations and correlation with clinical phenotype.

Autor: Tirosh I; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Yamazaki Y; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., Frugoni F; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Ververs FA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Allenspach EJ; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Zhang Y; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md., Burns S; Institute for Immunity and Transplantation, University College London, London, United Kingdom; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom., Al-Herz W; Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait., Noroski L; Division of Allergy and Immunology, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex., Walter JE; Division of Pediatric Allergy/Immunology, University of South Florida and Johns Hopkins All Children's Hospital, St Petersburg, Fla., Gennery AR; Department of Pediatric Immunology, Newcastle Upon Tyne Hospital, NHS Foundation Trust, United Kingdom and Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., van der Burg M; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address: luigi.notarangelo2@nih.gov., Lee YN; Pediatric Department A and the Immunology Service, 'Edmond and Lily Safra' Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Ramat-Gan and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: yuneeya4u@gmail.com.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2019 Feb; Vol. 143 (2), pp. 726-735. Date of Electronic Publication: 2018 Jun 18.

Characterization of T and B cell repertoire diversity in patients with RAG deficiency.

Autor: Lee YN; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Pediatric Department A and the Immunology Service, 'Edmond and Lily Safra' Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Frugoni F; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Dobbs K; Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Tirosh I; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Du L; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Ververs FA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Ru H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA., Ott de Bruin L; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Adeli M; Pediatrics Department, Weill Cornell Medical College, Hamad Medical Corporation, Doha, Qatar., Bleesing JH; Division of Hematology/Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Buchbinder D; Division of Hematology, Children's Hospital Orange County, Orange County, CA 92868, USA., Butte MJ; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA., Cancrini C; DPUO, University Department of Pediatrics, Bambino Gesù Children's Hospital and University of Tor Vergata School of Medicine, Rome, Italy., Chen K; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA., Choo S; Department of Immunology, Royal Children's Hospital, Melbourne, Victoria, Australia., Elfeky RA; Department of Pediatric Allergy and Immunology, Children's Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Finocchi A; DPUO, University Department of Pediatrics, Bambino Gesù Children's Hospital and University of Tor Vergata School of Medicine, Rome, Italy., Fuleihan RL; Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Gennery AR; Department of Paediatric Immunology, Great North Children's Hospital, Newcastle Upon Tyne, U.K.; Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, U.K., El-Ghoneimy DH; Department of Pediatric Allergy and Immunology, Children's Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Henderson LA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Al-Herz W; Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait., Hossny E; Department of Pediatric Allergy and Immunology, Children's Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Nelson RP; Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Pai SY; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Patel NC; Division of Infectious Disease and Immunology, Department of Pediatrics, Levine Children's Hospital, Carolinas Medical Center, Charlotte, NC 28203, USA., Reda SM; Department of Pediatric Allergy and Immunology, Children's Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Soler-Palacin P; Paediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron University Hospital, Barcelona, Spain., Somech R; Pediatric Department A and the Immunology Service, 'Edmond and Lily Safra' Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Palma P; DPUO, University Department of Pediatrics, Bambino Gesù Children's Hospital and University of Tor Vergata School of Medicine, Rome, Italy., Wu H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA., Giliani S; A. Nocivelli Institute for Molecular Medicine, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Section of Medical Genetics, Department of Pathology, Spedali Civili di Bresia, Brescia, Italy., Walter JE; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Division of Pediatric Allergy/Immunology, University of South Florida, and Johns Hopkins All Children's Hospital, St. Petersburg, FL 33701, USA., Notarangelo LD; Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. luigi.notarangelo2@nih.gov.

Publikováno v: Science immunology [Sci Immunol] 2016 Dec 16; Vol. 1 (6). Date of Electronic Publication: 2016 Dec 16.