Epigenetische Inaktivierung des Tumor-Suppressor Kandidatengens PROX1 beim sporadischen Mammakarzinom

Autor: Versmold, B, Waha, A, Felsberg, J, Pietsch, T, Mallmann, P, Schmutzler, RK

Publikováno v: Zentralblatt für Gynäkologie; 20240101, Issue: Preprints

Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Autor: Engel, C., Versmold, B., Wappenschmidt, B., Simard, J., Easton, D.F., Peock, S., Cook, M., Oliver, C., Frost, D., Mayes, R., Evans, D.G., Eeles, R., Paterson, J., Brewer, C., McGuffog, L., Antoniou, A.C., Stoppa-Lyonnet, D., Sinilnikova, O.M., Barjhoux, L., Frenay, M., Michel, C., Leroux, D., Dreyfus, H., Toulas, C., Gladieff, L., Uhrhammer, N., Bignon, Y.J., Meindl, A., Arnold, N., Varon-Mateeva, R., Niederacher, D., Preisler-Adams, S., Kast, K., Deissler, H., Sutter, C., Gadzicki, D., Chenevix-Trench, G., Spurdle, A.B., Chen, X.Q., Beesley, J., Olsson, H., Kristoffersson, U., Ehrencrona, H., Liljegren, A., Luijt, R.B. van der, Os, T.A. van, Leeuwen, F.E. van, Domchek, S.M., Rebbeck, T.R., Nathanson, K.L., Osorio, A., Cajal, T.R.Y., Konstantopoulou, I., Benitez, J., Friedman, E., Kaufman, B., Laitman, Y., Mai, P.L., Greene, M.H., Nevanlinna, H., Aittomaki, K., Szabo, C.I., Caldes, T., Couch, F.J., Andrulis, I.L., Godwin, A.K., Hamann, U., Schmutzler, R.K., Epidemiological Study Familial Bre, Kathleen Cuningham Fdn Consortium, Sweden SWE-BRCA, Hereditary Breast Ovarian Canc Grp, Consortium Investigators Modifiers

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology; 19, pp 2859-2868 (2010)
Cancer Epidemiology, Biomarkers & Prevention, 19, 2859-68
Cancer Epidemiology Biomarkers & Prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Cancer epidemiology, biomarkers & prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers and Prevention, 19(11), 2859-2868
Cancer Epidemiology Biomarkers and Prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
Engel, C, Versmold, B, Wappenschmidt, B, Simard, J, Easton, D F, Peock, S, Cook, M, Oliver, C, Frost, D, Mayes, R, Evans, D G, Eeles, R, Paterson, J, Brewer, C, McGuffog, L, Antoniou, A C, Stoppa-Lyonnet, D, Sinilnikova, O M, Barjhoux, L, Frenay, M, Michel, C, Leroux, D, Dreyfus, H, Toulas, C, Gladieff, L, Uhrhammer, N, Bignon, Y J, Meindl, A, Arnold, N, Varon-Mateeva, R, Niederacher, D, Preisler-Adams, S, Kast, K, Deissler, H, Sutter, C, Gadzicki, D, Chenevix-Trench, G, Spurdle, A B, Chen, X Q, Beesley, J, Olsson, H, Kristoffersson, U, Ehrencrona, H, Liljegren, A, van der Luijt, R B, Os, T A, van Leeuwen, F E, Domchek, S M, Rebbeck, T R, Nathanson, K L, Osorio, A, Cajal, T R Y, Konstantopoulou, I, Benitez, J, Friedman, E, Kaufman, B, Laitman, Y, Mai, P L, Greene, M H, Nevanlinna, H, Aittomaki, K, Szabo, C I, Caldes, T, Couch, F J, Andrulis, I L, Godwin, A K, Hamann, U & Schmutzler, R K 2010, ' Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 19, no. 11, pp. 2859-2868 . https://doi.org/10.1158/1055-9965.EPI-10-0517
Cancer Epidemiology, Biomarkers & Prevention, 19, 11, pp. 2859-68

Background: The genes caspase-8 (CASP8) and caspase-10 (CASP10) functionally cooperate and play a key role in the initiation of apoptosis. Suppression of apoptosis is one of the major mechanisms underlying the origin and progression of cancer. Previo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b194bf23b5a5ed942587889b64219a4b
https://lup.lub.lu.se/record/1710693

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

Autor: Antoniou, AC, Sinilnikova, OM, McGuffog, L, Healey, S, Nevanlinna, H, Heikkinen, T, Simard, J, Spurdle, AB, Beesley, J, Chen, XQ, Neuhausen, SL, Ding, YC, Couch, FJ, Wang, XS, Fredericksen, Z, Peterlongo, P, Peissel, B, Bonanni, B, Viel, A, Bernard, L, Radice, P, Szabo, CI, Foretova, L, Zikan, M, Claes, K, Greene, MH, Mai, PL, Rennert, G, Lejbkowicz, F, Andrulis, IL, Ozcelik, H, Glendon, G, Gerdes, AM, Thomassen, M, Sunde, L, Caligo, MA, Laitman, Y, Kontorovich, T, Cohen, S, Kaufman, B, Dagan, E, Baruch, RG, Friedman, E, Harbst, K, Barbany-Bustinza, G, Rantala, J, Ehrencrona, H, Karlsson, P, Domchek, SM, Nathanson, KL, Osorio, A, Blanco, I, Lasa, A, Benitez, J, Hamann, U, Hogervorst, FBL, Rookus, MA, Collee, JM, Devilee, P, Ligtenberg, MJ, van der Luijt, RB, Aalfs, CM, Waisfisz, Q, Wijnen, J, van Roozendaal, CEP, Peock, S, Cook, M, Frost, D, Oliver, C, Platte, R, Evans, DG, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Cole, T, Hodgson, S, Godwin, AK, Stoppa-Lyonnet, D, Buecher, B, Leone, M, Bressac-de Paillerets, B, Remenieras, A, Caron, O, Lenoir, GM, Sevenet, N, Longy, M, Ferrer, SF, Prieur, F, Goldgar, D, Miron, A, John, EM, Buys, SS, Daly, MB, Hopper, JL, Terry, MB, Yassin, Y, Singer, C, Gschwantler-Kaulich, D, Staudigl, C, Hansen, TVO, Barkardottir, RB, Kirchhoff, T, Pal, P, Kosarin, K, Offit, K, Piedmonte, M, Rodriguez, GC, Wakeley, K, Boggess, JF, Basil, J, Schwartz, PE, Blank, SV, Toland, AE, Montagna, M, Casella, C, Imyanitov, EN, Allavena, A, Schmutzler, RK, Versmold, B, Engel, C, Meindl, A, Ditsch, N, Arnold, N, Niederacher, D, Deissler, H, Fiebig, B, Suttner, C, Schonbuchner, I, Gadzicki, D, Caldes, T, de la Hoya, M, Pooley, KA, Easton, DF, Chenevix-Trench, G

Publikováno v: HUMAN MOLECULAR GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Genome-wide association studies of breast cancer have identified multiple single nucleotide polymorphisms (SNPs) that are associated with increased breast cancer risks in the general population. In a previous study, we demonstrated that the minor all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::719017cd34ce7939b9aa66f7dd0d74f3
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12952

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