Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro .

Autor: Stone NE; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Jaramillo SA; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Jones AN; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Vazquez AJ; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Martz M; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Versluis LM; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., Raniere MO; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., Nunnally HE; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Zarn KE; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Nottingham R; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Ng KR; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA., Sahl JW; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., Wagner DM; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., Knudsen S; Allarity Therapeutics, Hørsholm, Denmark., Settles EW; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., Keim P; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA., French CT; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA ctfrench@nau.edu.; Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA.

Publikováno v: MBio [mBio] 2021 Jan 19; Vol. 12 (1). Date of Electronic Publication: 2021 Jan 19.