Transport of topoisomerase I inhibitors by the breast cancer resistance protein - Potential clinical implications

Autor: Schellens, JHM, Maliepaard, M, Scheper, RJ, Scheffer, GL, Jonker, JW, Smit, JW, Beijnen, JH, Schinkel, AH, Liehr, JG, Giovanella, BC, Verschaegen, CF

Publikováno v: CAMPTOTHECINS: UNFOLDING THEIR ANTICANER POTENTIAL, 188-194
STARTPAGE=188;ENDPAGE=194;TITLE=CAMPTOTHECINS: UNFOLDING THEIR ANTICANER POTENTIAL

The multidrug resistance protein BCRP (breast cancer resistance protein) is a member of the ATP-binding cassette family of drug transporters. Overexpression of BCRP caused by exposure of cells to mitoxantrone (MX) or doxorubicin/verapamil resulted in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1b4ed4338f0de0d57919a0a6572b0d1c
https://research.rug.nl/en/publications/92a03833-7106-4db5-81f0-cb3a25760aa8