Spleen tyrosine kinase: a novel pharmacological target for sepsis-induced cardiac dysfunction and multi-organ failure.

Autor: Verra C; Centre for Translational Medicine and Therapeutics, William Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, United Kingdom., Paulmann MK; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.; Septomics Research Center, Jena University Hospital, Jena, Germany., Wegener J; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.; Septomics Research Center, Jena University Hospital, Jena, Germany., Marzani E; Department of Neurosciences 'Rita Levi Montalcini', University of Turin, Turin, Italy., Ferreira Alves G; Pharmacology Unit, School of Pharmacy, University of Camerino, Camerino, Italy., Collino M; Department of Neurosciences 'Rita Levi Montalcini', University of Turin, Turin, Italy., Coldewey SM; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.; Septomics Research Center, Jena University Hospital, Jena, Germany., Thiemermann C; Centre for Translational Medicine and Therapeutics, William Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Nov 04; Vol. 15, pp. 1447901. Date of Electronic Publication: 2024 Nov 04 (Print Publication: 2024).

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RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis.

Autor: Mohammad S; William Harvey Research Institute, Queen Mary University of London, London, United Kingdom., O'Riordan CE; William Harvey Research Institute, Queen Mary University of London, London, United Kingdom., Verra C; William Harvey Research Institute, Queen Mary University of London, London, United Kingdom., Aimaretti E; Department of Clinical and Biological Sciences, University of Turin, Turin, Italy., Alves GF; Department of Neurosciences 'Rita Levi Montalcini', University of Turin, Turin, Italy., Dreisch K; Red Glead Discovery Akiebolag (AB), Lund, Sweden., Evenäs J; Red Glead Discovery Akiebolag (AB), Lund, Sweden., Gena P; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari, Italy., Tesse A; Nantes Université, Instite National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Rescherche Scientifique (CNRS), l'institut du Thorax, Nantes, France., Rützler M; Department of Biochemistry and Structural Biology, Lund University, Lund, Sweden.; Apoglyx Akiebolag (AB), Lund, Sweden., Collino M; Department of Neurosciences 'Rita Levi Montalcini', University of Turin, Turin, Italy., Calamita G; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari, Italy., Thiemermann C; William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Jun 14; Vol. 13, pp. 900906. Date of Electronic Publication: 2022 Jun 14 (Print Publication: 2022).

Peroxiporins and Oxidative Stress: Promising Targets to Tackle Inflammation and Cancer.

Autor: da Silva, Inês V.^1,2 (AUTHOR) imsilva1@edu.ulisboa.pt, Mlinarić, Monika³ (AUTHOR), Lourenço, Ana Rita^1,2 (AUTHOR), Pérez-Garcia, Olivia^1,2 (AUTHOR), Čipak Gašparović, Ana³ (AUTHOR), Soveral, Graça^1,2 (AUTHOR) imsilva1@edu.ulisboa.pt

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8381. 18p.

AQP3 and AQP9—Contrary Players in Sepsis?

Autor: Thon, Patrick¹ (AUTHOR) patrick.thon@rub.de, Rahmel, Tim¹ (AUTHOR) tim.rahmel@rub.de, Ziehe, Dominik¹ (AUTHOR) dominik.ziehe@rub.de, Palmowski, Lars¹ (AUTHOR) lars.palmowski@kk-bochum.de, Marko, Britta¹ (AUTHOR) britta.marko@kk-bochum.de, Nowak, Hartmuth^1,2 (AUTHOR) hartmuth.nowak@kk-bochum.de, Wolf, Alexander¹ (AUTHOR) andrea.witowski@kk-bochum.de, Witowski, Andrea¹ (AUTHOR) jennifer.orlowski@kk-bochum.de, Orlowski, Jennifer¹ (AUTHOR) barbara.sitek@rub.de, Ellger, Björn³ (AUTHOR) bjoern.ellger@klinikum-westfalen.de, Wappler, Frank⁴ (AUTHOR) wapplerf@kliniken-koeln.de, Schwier, Elke⁵ (AUTHOR) elke.schwier@klinikum-herford.de, Henzler, Dietrich⁵ (AUTHOR) dietrich.henzler@klinikum-herford.de, Köhler, Thomas⁵ (AUTHOR) thomas.koehler@ruhr-uni-bochum.de, Zarbock, Alexander⁶ (AUTHOR) zarbock@uni-muenster.de, Ehrentraut, Stefan Felix⁷ (AUTHOR) stefan.ehrentraut@ukbonn.de, Putensen, Christian⁷ (AUTHOR) christian.putensen@ukbonn.de, Frey, Ulrich Hermann⁸ (AUTHOR) ulrich.frey@elisabethgruppe.de, Anft, Moritz⁹ (AUTHOR) moritz.anft@elisabethgruppe.de, Babel, Nina⁹ (AUTHOR) nina.babel@elisabethgruppe.de

Publikováno v: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 2, p1209. 12p.