Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Veronique Preat"'
Autor:
Spela Kos, Alessandra Lopes, Veronique Preat, Maja Cemazar, Ursa Lampreht Tratar, Bernard Ucakar, Kevin Vanvarenberg, Gregor Sersa, Gaelle Vandermeulen
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217762 (2019)
We aimed to explore whether the combination of intradermal DNA vaccination, to boost immune response against melanoma antigens, and immune checkpoint blockade, to alleviate immunosuppression, improves antitumor effectiveness in a murine B16F10 melano
Externí odkaz:
https://doaj.org/article/a51058ce69a64fbf8f44ce52ef40d79c
Autor:
Natasa Tesic, Urska Kamensek, Gregor Sersa, Simona Kranjc, Monika Stimac, Ursa Lampreht, Veronique Preat, Gaelle Vandermeulen, Miha Butinar, Boris Turk, Maja Cemazar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Endoglin (CD105), a transforming growth factor (TGF)-β coreceptor, and endothelin-1, a vasoconstrictor peptide, are both overexpressed in tumor endothelial and melanoma cells. Their targeting is therefore a promising therapeutic approach for melanom
Externí odkaz:
https://doaj.org/article/8a4f293de1854b56a574d23ba05e0ed4
Autor:
Thibaut Fourniols, Valentina Maggio, Diana Rafael, Ariana Colaco, Elia García Vidal, Alessandra Lopes, Simo Schwartz, Águeda Martínez-Barriocanal, Veronique Preat, Diego Arango
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 171:39-49
Bromodomain and extraterminal domain protein inhibitors (BETi) for cancer treatment did not convince during their first clinical trials. Their epigenetic mechanism of action is still not well understood, even if MYC is generally considered as its mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa4c83afb57b1fc79abd5f3846d8b84
https://doi.org/10.1016/j.ejpb.2021.10.017
https://doi.org/10.1016/j.ejpb.2021.10.017
Autor:
Patrik Lundquist, Georgiy Khodus, Zhigao Niu, Lungile Nomcebo Thwala, Fiona McCartney, Ivailo Simoff, Ellen Andersson, Ana Beloqui, Aloise Mabondzo, Sandra Robla, Dominic-Luc Webb, Per M. Hellström, Åsa V Keita, Eduardo Sima, Noemi Csaba, Magnus Sundbom, Veronique Preat, David J. Brayden, Maria Jose Alonso, Per Artursson
Publikováno v:
ACS nano, Vol. 16, no.9, p. 14210-14229 (2022)
Peptide drugs and biologics provide opportunities for treatments of many diseases. However, due to their poor stability and permeability in the gastrointestinal tract, the oral bioavailability of peptide drugs is negligible. Nanoparticle formulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77a6fefa0d21b8d5b5ff60bcb0e1237
https://pubmed.ncbi.nlm.nih.gov/35998570
https://pubmed.ncbi.nlm.nih.gov/35998570
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The poor delivery of drugs to infiltrating tumor cells contributes to therapeutic failure in glioblastoma. During the early phase of an anti-angiogenic treatment, a remodeling of the tumor vasculature could occur, leading to a
Externí odkaz:
https://doaj.org/article/50edb14b1902481ebd64930d2cc9edd6
Autor:
Teenesha Chellen, Mathilde Bausart, Pierre Maus, Kevin Vanvarenberg, Nisha Limaye, Véronique Préat, Alessio Malfanti
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101057- (2024)
Glioblastoma (GBM) is an aggressive brain tumor, with a highly immunosuppressive tumor immune microenvironment (TIME). In this work, we investigated the use of the STimulator of INterferon Genes (STING) pathway as an effective means to remodel the GB
Externí odkaz:
https://doaj.org/article/8706bd35314b47c0ba41325e3a3ecd79
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100147- (2023)
We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS2000) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC12) for t
Externí odkaz:
https://doaj.org/article/06d9894bef1c411b9e3c30477f7f8848
Autor:
Veronique Preat
Publikováno v:
Journal of Pharmaceutics & Drug Delivery Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f7c797fbfc8f6319e8bc55606bb480f
https://doi.org/10.4172/2325-9604-c2-028
https://doi.org/10.4172/2325-9604-c2-028
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1091 (2024)
(1) Background: Glioblastoma (GB) presents a formidable challenge in neuro-oncology due to its aggressive nature, limited treatment options, and poor prognosis. The blood–brain barrier (BBB) complicates treatment by hindering drug delivery to the t
Externí odkaz:
https://doaj.org/article/f9072b5a0cf5413a95d52c8bfe97f814
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-22 (2022)
Abstract Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy. In recent years, immunotherapy s
Externí odkaz:
https://doaj.org/article/9a1fda044bd3412fba4a59d1669caa3a