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pro vyhledávání: '"Veronique Harten"'
Publikováno v:
Immunogenetics. 52:121-128
Human MHC class I molecules are encoded by three different loci (HLA-A, -B, and -C), which are regulated at the transcriptional level through several conserved cis-acting promoter elements. The presence of locus-specific residues throughout the entir
Autor:
Marieke Griffioen, P.I. Schrier, Ilse J.M. Ouwerkerk, P.J. van den Elsen, Veronique Harten, Sam J. P. Gobin
Publikováno v:
Immunogenetics. 49:287-294
Tumor cells are thought to escape immune surveillance from T cells by suppressing expression of major histocompatibility complex (MHC) class I molecules at their cell surface. Human MHC class I molecules are encoded by three different loci (HLA-A, -B
Publikováno v:
International Journal of Cancer. 80:573-580
Major histocompatibility complex (MHC, HLA in humans) class I molecules play an important role in cellular immunology by presenting viral, tumor-associated or minor histocompatibility antigen-derived peptides to T cells. Tumor cells frequently fail t