Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Veronique Guyonnet-Duperat"'
Autor:
Julian Boutin, Coralie Genevois, Franck Couillaud, Isabelle Lamrissi-Garcia, Veronique Guyonnet-Duperat, Alice Bibeyran, Magalie Lalanne, Samuel Amintas, Isabelle Moranvillier, Emmanuel Richard, Jean-Marc Blouin, Sandrine Dabernat, François Moreau-Gaudry, Aurélie Bedel
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200772- (2024)
Thanks to its very high genome-editing efficiency, CRISPR-Cas9 technology could be a promising anticancer weapon. Clinical trials using CRISPR-Cas9 nuclease to ex vivo edit and alter immune cells are ongoing. However, to date, this strategy still has
Externí odkaz:
https://doaj.org/article/8586f0b7fa564304a6d3f7b12a589090
Autor:
Laetitia Dard, Christophe Hubert, Pauline Esteves, Wendy Blanchard, Ghina Bou About, Lyla Baldasseroni, Elodie Dumon, Chloe Angelini, Mégane Delourme, Véronique Guyonnet-Dupérat, Stéphane Claverol, Laura Fontenille, Karima Kissa, Pierre-Emmanuel Séguéla, Jean-Benoît Thambo, Lévy Nicolas, Yann Herault, Nadège Bellance, Nivea Dias Amoedo, Frédérique Magdinier, Tania Sorg, Didier Lacombe, Rodrigue Rossignol
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Germline mutations that activate genes in the canonical RAS/MAPK signaling pathway are responsible for rare human developmental disorders known as RASopathies. Here, we analyzed the molecular determinants of Costello syndrome (CS) using a mouse model
Externí odkaz:
https://doaj.org/article/efecf1351ff2484ba90767b2754d4938
Autor:
Grégoire Cullot, Julian Boutin, Jérôme Toutain, Florence Prat, Perrine Pennamen, Caroline Rooryck, Martin Teichmann, Emilie Rousseau, Isabelle Lamrissi-Garcia, Véronique Guyonnet-Duperat, Alice Bibeyran, Magalie Lalanne, Valérie Prouzet-Mauléon, Béatrice Turcq, Cécile Ged, Jean-Marc Blouin, Emmanuel Richard, Sandrine Dabernat, François Moreau-Gaudry, Aurélie Bedel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CRISPR-Cas9 has been rapidly adopted to generate cell line models of disease. Here the authors show, while attempting to establish a congenital erythropoietic porphyria model, unexpected chromosome truncations generated by a p53-dependent mechanism.
Externí odkaz:
https://doaj.org/article/3a225f969b444010a97c3369c573fb50
Autor:
Delphine Lapaillerie, Cathy Charlier, Henrique S. Fernandes, Sergio F. Sousa, Paul Lesbats, Pierre Weigel, Alexandre Favereaux, Véronique Guyonnet-Duperat, Vincent Parissi
Publikováno v:
Viruses, Vol 13, Iss 3, p 365 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent responsible for the recent coronavirus disease 2019 (COVID-19) pandemic. Productive SARS-CoV-2 infection relies on viral entry into cells expressing angiotensin-conve
Externí odkaz:
https://doaj.org/article/803dd776d12e4d34b7d771c584205842