Clinical trials in pediatric ALS: a TRICALS feasibility study

Autor: Tessa Kliest, Ruben P.A. Van Eijk, Ammar Al-Chalabi, Alberto Albanese, Peter M. Andersen, Maria Del Mar Amador, Geir BrÅthen, Veronique Brunaud-Danel, Lev Brylev, William Camu, Mamede De Carvalho, Cristina Cereda, Hakan Cetin, Delia Chaverri, Adriano Chiò, Philippe Corcia, Philippe Couratier, Fabiola De Marchi, Claude Desnuelle, Michael A. Van Es, JesÚs Esteban, Massimiliano Filosto, Alberto GarcÍa Redondo, Julian Grosskreutz, Clemens O. Hanemann, Trygve HolmØy, Helle HØyer, Caroline Ingre, Blaz Koritnik, Magdalena Kuzma-Kozakiewicz, Thomas Lambert, Peter N. Leigh, Christian Lunetta, Jessica Mandrioli, Christopher J. Mcdermott, Thomas Meyer, Jesus S. Mora, Susanne Petri, MÓnica Povedano, Evy Reviers, Nilo Riva, Kit C.B. Roes, Miguel Á. Rubio, FranÇois Salachas, Stayko Sarafov, Gianni SorarÙ, Zorica Stevic, Kirsten Svenstrup, Anette Torvin MØller, Martin R. Turner, Philip Van Damme, Lucie A.G. Van Leeuwen, Luis Varona, Juan F. VÁzquez Costa, Markus Weber, Orla Hardiman, Leonard H. Van Den Berg

Publikováno v: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2022, pp.1-8. ⟨10.1080/21678421.2021.2024856⟩
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23, 481-488
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23, 7-8, pp. 481-488
Kliest, T, Van Eijk, R P A, Al-Chalabi, A, Albanese, A, Andersen, P M, Amador, M D M, BrÅthen, G, Brunaud-Danel, V, Brylev, L, Camu, W, De Carvalho, M, Cereda, C, Cetin, H, Chaverri, D, Chiò, A, Corcia, P, Couratier, P, De Marchi, F, Desnuelle, C, Van Es, M A, Esteban, J, Filosto, M, GarcÍa Redondo, A, Grosskreutz, J, Hanemann, C O, HolmØy, T, HØyer, H, Ingre, C, Koritnik, B, Kuzma-Kozakiewicz, M, Lambert, T, Leigh, P N, Lunetta, C, Mandrioli, J, Mcdermott, C J, Meyer, T, Mora, J S, Petri, S, Povedano, MÓ, Reviers, E, Riva, N, Roes, K C B, Rubio, M, Salachas, F, Sarafov, S, SorarÙ, G, Stevic, Z, Svenstrup, K, MØller, A T, Turner, M R, Van Damme, P, Van Leeuwen, L A G, Varona, L, VÁzquez Costa, J F, Weber, M, Hardiman, O & Van Den Berg, L H 2022, ' Clinical trials in pediatric ALS : a TRICALS feasibility study ', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol. 23, no. 7-8, pp. 481-488 . https://doi.org/10.1080/21678421.2021.2024856

Background: Pediatric investigation plans (PIPs) describe how adult drugs can be studied in children. In 2015, PIPs for Amyotrophic Lateral Sclerosis (ALS) became mandatory for European marketing-authorization of adult treatments, unless a waiver is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fe6c6cded34ce9af67049e3ef23c06
https://hal-unilim.archives-ouvertes.fr/hal-03673852

AgroDataRing: Une infrastructure partagée et mutualisée pour le stockage longue durée

Autor: Pierre Adenot, Stéphane Bansard, David Benaben, Veronique Brunaud, Christophe Caron, Alexandre Dehne Garcia, Christophe Duperier, Adrien Falce, Olivier Filangi, Franck Giacomoni, Fabienne Granier, Philippe Grevet, Nicolas Guilhot, Annie Hofstetter, Johann Joets, Thierry Hotelier, Olivier Langella, Ludovic Legrand, Mikaël Loaec, Virginie Lollier, Patrick Moreau, Emmanuelle Morin, Hadi Quesneville, Tovo Rabemanantsoa, Gerald Salin, Dominique Tessier

Publikováno v: Cahier des Techniques de l'INRA
Cahier des Techniques de l'INRA, INRA, 2018, pp.1-7
HAL
Cahier des Techniques de l'INRA, 2018, pp.1-7

National audience; Les communautés scientifiques se trouvent aujourd’hui confrontées à un changement de paradigme autour de la gestion des données, nécessitant une meilleure gestion du cycle de vie des données avec notamment leur traitement e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1cc5064d86ef5613bce093659b6749de
https://hal.archives-ouvertes.fr/hal-02097192/document

Evolutionary analyses and expression patterns of TCP genes in Ranunculales

Autor: Catherine Damerval, Carmine Claudot, Martine Le Guilloux, Natalia Conde e Silva, Véronique Brunaud, Ludivine Soubigou-Taconnat, José Caius, Etienne Delannoy, Sophie Nadot, Florian Jabbour, Yves Deveaux

Publikováno v: Frontiers in Plant Science, Vol 13 (2022)

TCP transcription factors play a role in a large number of developmental processes and are at the crossroads of numerous hormonal biosynthetic and signaling pathways. The complete repertoire of TCP genes has already been characterized in several plan

Externí odkaz: https://doaj.org/article/ed8a04be9fdb4e77b905b9c7b8764588

A comprehensive map of preferentially located motifs reveals distinct proximal cis-regulatory sequences in plants

Autor: Julien Rozière, Cécile Guichard, Véronique Brunaud, Marie-Laure Martin, Sylvie Coursol

Publikováno v: Frontiers in Plant Science, Vol 13 (2022)

Identification of cis-regulatory sequences controlling gene expression is an arduous challenge that is being actively explored to discover key genetic factors responsible for traits of agronomic interest. Here, we used a genome-wide de novo approach

Externí odkaz: https://doaj.org/article/6e4edc27296543ed97a38c8b971c3ef6

Transcriptome Analysis Reveals Putative Target Genes of APETALA3-3 During Early Floral Development in Nigella damascena L.

Autor: Yves Deveaux, Natalia Conde e Silva, Domenica Manicacci, Martine Le Guilloux, Véronique Brunaud, Harry Belcram, Johann Joets, Ludivine Soubigou-Taconnat, Etienne Delannoy, Hélène Corti, Sandrine Balzergue, Jose Caius, Sophie Nadot, Catherine Damerval

Publikováno v: Frontiers in Plant Science, Vol 12 (2021)

Even though petals are homoplastic structures, their identity consistently involves genes of the APETALA3 (AP3) lineage. However, the extent to which the networks downstream of AP3 are conserved in species with petals of different evolutionary origin

Externí odkaz: https://doaj.org/article/dec21d9e081642349285240186c08277