Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Veronique Maes"'
Publikováno v:
Journal of Flow Chemistry. 10:673-679
Functional acrylamides are valuable intermediates for organic synthesis and building blocks in many industrial areas, like polymer synthesis, fine chemicals and pharmaceutics. The conventional batch reaction copes with some safety issues, due to the
Publikováno v:
Reaction Chemistry & Engineering. 3:41-47
An efficient, safe and convenient laboratory scale continuous flow process for synthesis of (meth)acrylate monomers is described. (Meth)acryloyl chloride is reacted with n-octanol and other alcohols in the presence of triethyl amine in a tubular reac
Autor:
Dirk Tourwé, Ambikaipakan Balasubramaniam, Paul Boon, Jean-Jacques Bourguignon, Jean-Paul Humbert, Martine Schmitt, An De Prins, Jeanelle Portelli, Alfred Meurs, Isabelle Bertin, Frédéric Simonin, Frédéric Bihel, Jessica Coppens, Ilse Julia Smolders, Veronique Maes, Joery De Kock, Ann Massie, Tamara Vanhaecke, Valérie Utard, Ine Buffel, Hassan Hammoud
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2015, 95, pp.415-423. ⟨10.1016/j.neuropharm.2015.04.030⟩
Neuropharmacology, Elsevier, 2015, 95, pp.415-423. ⟨10.1016/j.neuropharm.2015.04.030⟩
Neuropeptide Y (NPY) is a well established anticonvulsant and first-in-class antiepileptic neuropeptide. In this study, the controversial role of NPY1 receptors in epilepsy was reassessed by testing two highly selective NPY1 receptor ligands and a mi
Autor:
Wouter Vanormelingen, Pieter Verstappen, Dirk Vanderzande, Wouter Maes, Laurence Lutsen, Veronique Maes, David Bevk
Publikováno v:
Synlett. 24:2389-2392
A two-step synthetic protocol involving (i) a Wittig-type carbonyl olefination, and (ii) regioselective alkylation of the exocyclic double bond with LiAlH4 and an alkyl bromide, was developed as an alternative to the recently reported three-step synt
Autor:
Dirk Tourwé, Elisa Garcia-Garayoa, Veronique Maes, Luc Brans, Christian Schweinsberg, Harriet Struthers, Roger Schibli
Publikováno v:
ChemMedChem. 5:1717-1725
Overexpression of the gastrin-releasing peptide receptor (GRPR) in a variety of human carcinomas has provided a means of diagnosis and treatment. Previously we reported a metabolically stable (N(α)His)Ac-βAla-βAla-[Cha(13),Nle(14)]BBS(7-14) analog
Autor:
Christian Schweinsberg, Peter Bläuenstein, Dirk Tourwé, Veronique Maes, Roger Schibli, P. August Schubiger, Elisa Garcia-Garayoa, Luc Brans, Simone Daepp
Publikováno v:
Chemical Biology & Drug Design. 72:496-506
The overexpression of peptide receptors in a variety of human carcinomas has generated considerable interest in peptide-based radiopharmaceuticals for peptide receptor imaging and peptide receptor radiotherapy. The gastrin-releasing peptide receptor
Autor:
Christian Schweinsberg, Elisa García Garayoa, Dirk Tourwé, P. August Schubiger, Peter Bläuenstein, Veronique Maes, Roger Schibli, Luc Brans
Publikováno v:
Bioconjugate Chemistry. 19:2432-2439
Radiolabeled bombesin (BBS) analogues are promising pharmaceuticals for imaging of cancer cells expressing gastrin-releasing peptide receptors (GRPR). However, most of the radiolabeled BBS derivatives show a high accumulation of activity in the liver
Autor:
Dirk Tourwé, Roger Schibli, P. August Schubiger, Christian Schweinsberg, Veronique Maes, Luc Brans, Elisa García Garayoa, Peter Bläuenstein
Publikováno v:
Bioconjugate Chemistry. 19:2409-2416
The overexpression of Bombesin (BBS) receptors on a variety of human cancers make them interesting targets for tumor imaging and therapy. Analogues of the neuropeptide BBS have been functionalized with the (NalphaHis)- chelator for labeling with the
Autor:
Veronique Maes, D. Tourwe, P. August Schubiger, Peter Bläuenstein, Elisa Garcia-Garayoa, Alain Blanc
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging, 36 (1)
European Journal of Nuclear Medicine and Molecular Imaging, 36 (1)
ISSN:1619-7070
ISSN:1619-7089
ISSN:1619-7070
ISSN:1619-7089
Autor:
Dirk Tourwé, Alain Blanc, Veronique Maes, Martin Zwimpfer, P. August Schubiger, Irfan Ullah Khan, Annette G. Beck-Sickinger, Peter Bläuenstein, Dominique Rüegg, Elisa García Garayoa
Publikováno v:
Nuclear Medicine and Biology. 34:17-28
Bombesin, a neuropeptide with potential for breast and prostate tumor targeting, is rapidly metabolized in vivo, and as a result, uptake in tumor xenografts in mice is poor. An improvement can be expected from the introduction of nonnatural amino aci