Výsledky vyhledávání - "Veronika Tomkova"

Figure S1 from Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

Autor: Jaroslav Truksa, Lukas Werner, Jan Stursa, Jiri Neuzil, Jan Brábek, Daniel Rosel, Miroslava K. Adamcová, Sandra Lettlova, Ladislav Merta, Kristyna Blazkova, Sukanya B. Jadhav, Veronika Tomkova, Natalia Torrealba, Cristian Sandoval-Acuña

High Resolution Supplementary Figure 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc81a9805f61201c2c5e513b1e34620
https://doi.org/10.1158/0008-5472.22430629

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Data from Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

Deferoxamine (DFO) represents a widely used iron chelator for the treatment of iron overload. Here we describe the use of mitochondrially targeted deferoxamine (mitoDFO) as a novel approach to preferentially target cancer cells. The agent showed mark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40826994687882bae8f7da906f56f1d7
https://doi.org/10.1158/0008-5472.c.6513664

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Figure S4 from Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

High Resolution Supplementary Figure S4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b0eb7d7559b37c93a5a4c6d9c6dcd2
https://doi.org/10.1158/0008-5472.22430620

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Figure S2 from Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

High Resolution Supplementary Figure 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a1704f685463b4b5a5d37e89f4f144
https://doi.org/10.1158/0008-5472.22430626.v1

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Supplementary Data from Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

Supplementary Methods, Tables and Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299f3af6fe6d66d16fa35150bf1ad431
https://doi.org/10.1158/0008-5472.22430614.v1

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Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy

Autor: Ladislav Merta, Natalia Torrealba, Jaroslav Truksa, Jan Stursa, Jiri Neuzil, Lukas Werner, Daniel Rösel, Veronika Tomkova, Kristyna Blazkova, Jan Brábek, Sandra Lettlova, Sukanya Balkrishna Jadhav, Miroslava Kari Adamcová, Cristian Sandoval-Acuña

Publikováno v: Cancer Research. 81:2289-2303

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e1541bc5830526b4b0452ad972a170
https://doi.org/10.1158/0008-5472.can-20-1628

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Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells

Autor: Natalia Torrealba, Veronika Tomkova, Cristian Sandoval-Acuña, Jaroslav Truksa

Publikováno v: Free radical biologymedicine. 143

Tamoxifen resistance remains a clinical obstacle in the treatment of hormone sensitive breast cancer. It has been reported that tamoxifen is able to target respiratory complex I within mitochondria. Therefore, we established two tamoxifen-resistant c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acda3eb8b0964a11e85738352b0bb80a
https://pubmed.ncbi.nlm.nih.gov/31494243

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Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism

Autor: Jaroslav Truksa, Veronika Tomkova, Polina Zjablovskaja, Vlasta Korenkova, Ekaterina Simonova, Sandra Lettlova, Meritxell Alberich-Jorda, Lucie Langerova, Zuzana Rychtarcikova, Jiri Neuzil

Publikováno v: Oncotarget

// Zuzana Rychtarcikova 1, 2, * , Sandra Lettlova 1, 3, * , Veronika Tomkova 1, 3 , Vlasta Korenkova 1 , Lucie Langerova 1 , Ekaterina Simonova 1 , Polina Zjablovskaja 4 , Meritxell Alberich-Jorda 4 , Jiri Neuzil 1, 5 , Jaroslav Truksa 1 1 Institute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82de32eddd58aafe31d8cb233593cc68
https://doi.org/10.18632/oncotarget.14093

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Mitochondrial iron chelation as a novel anti-cancer strategy

Autor: Krystina Repkova, Cristian Sandoval-Acuña, Jaroslav Truksa, Veronika Tomkova, Jiri Neuzil, Natalia Torrealba Cardenas, Jan Stursa, Lukas Werner

Publikováno v: Free Radical Biology and Medicine. 120:S61

Iron is an indispensable micronutrient required for function of key cellular enzymes required for DNA replication and repair, and for mitochondrial respiration and metabolism. Within cells, iron is primarily utilized in mitochondria, where it is esse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f3c03fb76703b09f41444dd025133c8
https://doi.org/10.1016/j.freeradbiomed.2018.04.202

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