Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Veronika Furlan"'
Publikováno v:
Foods, Vol 13, Iss 17, p 2708 (2024)
In this study, a novel quantum mechanics-based protocol for the evaluation of carcinogen-scavenging activity (QM-CSA) is developed. The QM-CSA protocol represents a universal and quantitative approach to evaluate and compare the activation-free energ
Externí odkaz:
https://doaj.org/article/a8d47d77cca14e7ca0e421477f266168
Autor:
Ahmed Sabt, Stefanos Kitsos, Manal S Ebaid, Veronika Furlan, Panagiota D Pantiora, Magdalini Tsolka, Eslam B Elkaeed, Mohamed Farouk Hamissa, Nikolaos Angelis, Ourania E Tsitsilonis, Anastassios C Papageorgiou, Urban Bren, Nikolaos E Labrou
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0306124 (2024)
Multidrug resistance (MDR) mechanisms in cancer cells are greatly influenced by glutathione transferase P1-1 (hGSTP1-1). The use of synthetic or natural compounds as hGSTP1-1 inhibitors is considered an effective approach to overcome MDR. Nine compou
Externí odkaz:
https://doaj.org/article/a6fed7d923c14a768d9452355917c260
Autor:
Steliana Tsouri, Evanthia Tselo, Georgios E. Premetis, Veronika Furlan, Panagiota D. Pantiora, Barbara Mavroidi, Dimitris Matiadis, Maria Pelecanou, Anastassios C. Papageorgiou, Urban Bren, Marina Sagnou, Nikolaos E. Labrou
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 365 (2024)
Human glutathione transferase A4-4 (hGSTA4-4) displays high catalytic efficiency towards 4-hydroxyalkenals and other cytotoxic and mutagenic products of radical reactions and lipid peroxidation. Its role as a target for the chemosensitization of canc
Externí odkaz:
https://doaj.org/article/1c39e881fdbf4dc7948c349b505a5aa6
Autor:
Veronika Furlan, Urban Bren
Publikováno v:
Foods, Vol 12, Iss 4, p 802 (2023)
Helichrysum italicum (family Asteraceae), due to its various beneficial health effects, represents an important plant in the traditional medicine of Mediterranean countries. Currently, there is a renewed interest in this medicinal plant, especially i
Externí odkaz:
https://doaj.org/article/055d99cd07964dfeab6cdfa18393b7aa
Autor:
Panagiota Pantiora, Veronika Furlan, Dimitris Matiadis, Barbara Mavroidi, Fereniki Perperopoulou, Anastassios C. Papageorgiou, Marina Sagnou, Urban Bren, Maria Pelecanou, Nikolaos E. Labrou
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 63 (2022)
The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug resistance (MDR) mechanisms in numerous cancer cell lines. In the present study, the inhibition potency of two curcuminoids and eleven monocarbonyl curcumin anal
Externí odkaz:
https://doaj.org/article/3530422638f34370b6362ffaae42beb0
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2348 (2022)
Manganese Superoxide Dismutase (MnSOD) represents a mitochondrial protein that scavenges reactive oxygen species (ROS) responsible for oxidative stress. A known single nucleotide polymorphism (SNP) rs4880 on the SOD2 gene, causing a mutation from ala
Externí odkaz:
https://doaj.org/article/ccde657e4b1b4a418226ea3783a3f196
Publikováno v:
Foods, Vol 11, Iss 9, p 1253 (2022)
Natural products from plants exert a promising potential to act as antioxidants, antimicrobials, anti-inflammatory, and anticarcinogenic agents. Xanthohumol, a natural compound from hops, is indeed known for its anticarcinogenic properties. Xanthohum
Externí odkaz:
https://doaj.org/article/e933ede493ba4f4f93fa861f4a69e831
Autor:
Alja Štern, Veronika Furlan, Matjaž Novak, Martina Štampar, Zala Kolenc, Katarina Kores, Metka Filipič, Urban Bren, Bojana Žegura
Publikováno v:
Foods, Vol 10, Iss 6, p 1331 (2021)
The present study addresses the chemoprotective effects of xanthohumol (XN), a prenylated flavonoid found in the female inflorescences (hops) of the plant Humulus lupulus L., against the carcinogenic food contaminant aflatoxin B1 (AFB1). The chemical
Externí odkaz:
https://doaj.org/article/81b7b413fa14461b885caa07c50fef7b
Autor:
Veronika Furlan, Urban Bren
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 479 (2021)
Phosphodiesterase 4 (PDE4), mainly present in immune, epithelial, and brain cells, represents a family of key enzymes for the degradation of cyclic adenosine monophosphate (cAMP), which modulates inflammatory response. In recent years, the inhibition
Externí odkaz:
https://doaj.org/article/cf7e2323bc684ea5b3ae002ce56a74a3
Autor:
Veronika Furlan, Urban Bren
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 695 (2020)
[6]-Gingerol from ginger has received considerable attention as a potential cancer therapeutic agent because of its chemopreventive and chemotherapeutic effects, as well as its safety. In the current study, we examined [6]-gingerol as a natural scave
Externí odkaz:
https://doaj.org/article/eef40dbab4824b3b804259117f35ff06