Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Veronika Daniel Lišková"'
Autor:
Milan Kuchař, Petr Kosztyu, Veronika Daniel Lišková, Jiří Černý, Hana Petroková, Eliška Vróblová, Michal Malý, Lucie Vaňková, Michal Křupka, Leona Rašková Kafková, Pavlína Turánek Knotigová, Jarmila Dušková, Jan Dohnálek, Josef Mašek, Jaroslav Turánek, Milan Raška, Petr Malý
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1271-1287 (2021)
One of the proposed strategies for the development of a more efficient HIV-1 vaccine is based on the identification of proteins binding to a paratope of chosen broadly neutralizing antibody (bNAb) that will mimic cognate HIV-1 Env (glyco)protein epit
Externí odkaz:
https://doaj.org/article/e2fc21396ad441c3bd13ab1fc43190d2
Autor:
Veronika Daniel Lišková, Petr Kosztyu, Milan Kuchař, Jiří Černý, Shiv Bharadwaj, Hana Petroková, Eliška Vroblová, Michal Křupka, Michal Malý, Tereza Zosinčuková, Josef Šulc, Leona Rašková Kafková, Milan Raška, Petr Malý
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionImprinting broadly neutralizing antibody (bNAb) paratopes by shape complementary protein mimotopes represents a potential alternative for developing vaccine immunogens. This approach, designated as a Non-Cognate Ligand Strategy (NCLS), ha
Externí odkaz:
https://doaj.org/article/ec8d9f7e88b64853bdfbe5c783473a9a
Autor:
Andrea Schenkmayerova, Gaspar P. Pinto, Martin Toul, Martin Marek, Lenka Hernychova, Joan Planas-Iglesias, Veronika Daniel Liskova, Daniel Pluskal, Michal Vasina, Stephane Emond, Mark Dörr, Radka Chaloupkova, David Bednar, Zbynek Prokop, Florian Hollfelder, Uwe T. Bornscheuer, Jiri Damborsky
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Directed evolution commonly relies on point mutations but InDels frequently occur in evolution. Here the authors report a protein-engineering framework based on InDel mutagenesis and fragment transplantation resulting in greater catalysis and longer
Externí odkaz:
https://doaj.org/article/3c18b7a5373d42f0b49ea5eb1b1dcbad