Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Veronika Brynychová"'
Autor:
Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Pavel Souček
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2074-2089 (2023)
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling proteins. Using data from three h
Externí odkaz:
https://doaj.org/article/dc346fd6f49f495581f9e427e684f5cc
Autor:
Barbora Hanousková, Mikuláš Skála, Veronika Brynychová, Tomáš Zárybnický, Veronika Skarková, Petra Kazimírová, Andrea Vernerová, Pavel Souček, Lenka Skálová, Radek Pudil, Petra Matoušková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 115, Iss , Pp - (2019)
Cardiotoxicity is a serious adverse reaction to cancer chemotherapy and may lead to critical heart damage. Imatinib mesylate (IMB), a selective tyrosine kinase inhibitor, is sometimes accompanied by severe cardiovascular complications. To minimize ri
Externí odkaz:
https://doaj.org/article/89a1fd40aae64d828870352f9fd66c43
Autor:
Viktor Hlaváč, Radka Václavíková, Veronika Brynychová, Pavel Ostašov, Renata Koževnikovová, Katerina Kopečková, David Vrána, Jiří Gatěk, Pavel Souček
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2826 (2021)
Breast cancer is the most frequent cancer in the female population worldwide. The role of germline genetic variability in cytochromes P450 (CYP) in breast cancer prognosis and individualized therapy awaits detailed elucidation. In the present study,
Externí odkaz:
https://doaj.org/article/d62fec867dff44eaa6a7d8885d943d91
Autor:
Viktor Hlaváč, Radka Václavíková, Veronika Brynychová, Renata Koževnikovová, Katerina Kopečková, David Vrána, Jiří Gatěk, Pavel Souček
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9556 (2020)
Breast cancer is the most common cancer in women in the world. The role of germline genetic variability in ATP-binding cassette (ABC) transporters in cancer chemoresistance and prognosis still needs to be elucidated. We used next-generation sequencin
Externí odkaz:
https://doaj.org/article/beeb71dcf1cb42a8a5dc3976ed53e230
Autor:
Ivona Krus, Veronika Brynychová, Viktor Hlaváč, Radka Václavíková, Maria Kováčová, Renata Koževnikovová, Katerina Kopečková, Jannis Tornikidis, David Vrána, Jiří Gatěk, Pavel Souček
Publikováno v:
Molecular Diagnosis & Therapy. 26:665-678
Human kinesin 14 (KIF14) is one of the 70 prognostic marker genes (so-called Amsterdam profile) previously identified by the microarray of breast carcinomas, and its high transcript expression in tumor specimens indicates a poor prognosis for patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d7166c07298196142d27a3ba6187fb
https://doi.org/10.1007/s40291-022-00616-z
https://doi.org/10.1007/s40291-022-00616-z
Autor:
Petr Holý, Viktor Hlaváč, Pavel Ostašov, Veronika Brynychová, Renata Koževnikovová, Markéta Trnková, Kateřina Kopečková, Soňa Měšťáková, Marcela Mrhalová, Pavel Souček
Publikováno v:
Biochimie. 199
Oxysterols, oxidized derivatives of cholesterol, have been implicated in multiple pathologies, including cancer. In breast cancer, the link is especially strong due to interactions between oxysterols and estrogen receptor activity. Here, we provide t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b09f59f5a9172d30578a3937019d034
https://pubmed.ncbi.nlm.nih.gov/35525372
https://pubmed.ncbi.nlm.nih.gov/35525372
Autor:
Sandra Lettlova, Veronika Brynychova, Jan Blecha, David Vrana, Magdalena Vondrusova, Pavel Soucek, Jaroslav Truksa
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 6, Pp 2601-2615 (2018)
Background/Aims: MiRNA-301a-3p is an oncogenic miRNA whose expression is associated with tumor development, metastases and overall poor prognosis. Estrogen receptor α (ERα) is one of the estrogen hormone-activated transcription factors, which regul
Externí odkaz:
https://doaj.org/article/8cce9a721faa4e2a9c4187fb0bbb2157
Autor:
David Vrana, Viktor Hlavac, Veronika Brynychova, Radka Vaclavikova, Cestmir Neoral, Jiri Vrba, Rene Aujesky, Marcel Matzenauer, Bohuslav Melichar, Pavel Soucek
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 868 (2018)
The prognosis of esophageal cancer (EC) is poor, despite considerable effort of both experimental scientists and clinicians. The tri-modality treatment consisting of neoadjuvant chemoradiation followed by surgery has remained the gold standard over d
Externí odkaz:
https://doaj.org/article/1e3a5e912e2c4c64a8f43154e084e2ea
Autor:
Veronika Vymetalkova, Pavel Soucek, Tereza Kunicka, Katerina Jiraskova, Veronika Brynychova, Barbara Pardini, Vendula Novosadova, Zdena Polivkova, Katerina Kubackova, Renata Kozevnikovova, Miloslav Ambrus, Ludmila Vodickova, Alessio Naccarati, Pavel Vodicka
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134463 (2015)
Variations in the TP53 gene have been suggested to play a role in many cancers, including breast. We previously observed an association between TP53 haplotypes based on four polymorphisms (rs17878362, rs1042522, rs12947788, and rs17884306) and the ri
Externí odkaz:
https://doaj.org/article/daa9818343444ee98abf92c5511e42d0