Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Veronika Altmannová"'
Autor:
Veronika Altmannova, Mario Spirek, Lucija Orlic, Atis Jēkabsons, Tereza Clarence, Adrian Henggeler, Jarmila Mlcouskova, Raphaël A.G. Chaleil, Joao Matos, Lumir Krejci
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105439- (2022)
Summary: During meiosis, programmed DNA double-strand breaks (DSBs) are repaired by homologous recombination. DMC1, a conserved recombinase, plays a central role in this process. DMC1 promotes DNA strand exchange between homologous chromosomes, thus
Externí odkaz:
https://doaj.org/article/b1ba76f4797844b890a9b02c8b817ef3
Autor:
Dorota Rousová, Vaishnavi Nivsarkar, Veronika Altmannova, Vivek B Raina, Saskia K Funk, David Liedtke, Petra Janning, Franziska Müller, Heidi Reichle, Gerben Vader, John R Weir
Publikováno v:
eLife, Vol 10 (2021)
In meiosis, DNA double-strand break (DSB) formation by Spo11 initiates recombination and enables chromosome segregation. Numerous factors are required for Spo11 activity, and couple the DSB machinery to the development of a meiosis-specific ‘axis-t
Externí odkaz:
https://doaj.org/article/452bfa1c9307413da0e6b24aabfb3fc9
Publikováno v:
Biomolecules, Vol 2, Iss 3, Pp 350-375 (2012)
DNA double-strand breaks (DSBs) comprise one of the most toxic DNA lesions, as the failure to repair a single DSB has detrimental consequences on the cell. Homologous recombination (HR) constitutes an error-free repair pathway for the repair of DSBs.
Externí odkaz:
https://doaj.org/article/a03f7bd969df4ac9a7af18142fffd611
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Proper DNA replication is essential for faithful transmission of the genome. However, replication stress has serious impact on the integrity of the cell, leading to stalling or collapse of replication forks, and has been determine
Externí odkaz:
https://doaj.org/article/121410ae72b546699f2b61ab772eec5f
Autor:
Prabha Sarangi, Veronika Altmannova, Cory Holland, Zdenka Bartosova, Fanfan Hao, Dorothea Anrather, Gustav Ammerer, Sang Eun Lee, Lumir Krejci, Xiaolan Zhao
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 143-152 (2014)
Summary: DNA repair scaffolds mediate specific DNA and protein interactions in order to assist repair enzymes in recognizing and removing damaged sequences. Many scaffold proteins are dedicated to repairing a particular type of lesion. Here, we show
Externí odkaz:
https://doaj.org/article/f56841cc41524ee68b7396b83e363d1e
Autor:
Prabha Sarangi, Roland Steinacher, Veronika Altmannova, Qiong Fu, Tanya T Paull, Lumir Krejci, Matthew C Whitby, Xiaolan Zhao
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004899 (2015)
Protein modifications regulate both DNA repair levels and pathway choice. How each modification achieves regulatory effects and how different modifications collaborate with each other are important questions to be answered. Here, we show that sumoyla
Externí odkaz:
https://doaj.org/article/2a0d4b114b714d5795ce8234dcb3dc53