Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Veronika Akopian"'
Autor:
Alexander M. Tsankov, Aleksandra Alicja Arczewska, Tarjei S. Mikkelsen, Veronika Akopian, Alex K. Shalek, Zachary D. Smith, Alexander Meissner, Riley S. Drake, Benjamin E. Mead, Samuel J. Allon, Marc H. Wadsworth, Jocelyn Charlton
Publikováno v:
Development
Maintenance of pluripotency and specification towards a new cell fate are both dependent on precise interactions between extrinsic signals and transcriptional and epigenetic regulators. Directed methylation of cytosines by the de novo methyltransfera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f0833c2db7a0ab72d5f65f7c51a37
https://pubmed.ncbi.nlm.nih.gov/31515224
https://pubmed.ncbi.nlm.nih.gov/31515224
Autor:
Jocelyn Charlton, Kendell Clement, Zachary D. Smith, Ramona Pop, Alexander M. Tsankov, Bernd Timmermann, David Santos, Sven Klages, Michael J. Ziller, Veronika Akopian, Timothy L. Downing, Evangelos Kiskinis, Hongcang Gu, Alexander Meissner, Andreas Gnirke
Publikováno v:
Nature Structural and Molecular Biology
Nature structural & molecular biology
Nature structural & molecular biology
Cytosine methylation is widespread among organisms and essential for mammalian development. In line with early postulations of an epigenetic role in gene regulation, symmetric CpG methylation can be mitotically propagated over many generations with e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b95e192ce84cf64c6556994aa158c3a
https://hdl.handle.net/21.11116/0000-0000-E264-021.11116/0000-0000-E266-E
https://hdl.handle.net/21.11116/0000-0000-E264-021.11116/0000-0000-E266-E
Autor:
Casey A. Gifford, Laurence Daheron, Nadejda M. Tsankova, Alexander M. Tsankov, Sundari Chetty, Ramona Pop, Veronika Akopian, Alexander Meissner
Publikováno v:
Nature Biotechnology. 33:1182-1192
Research on human pluripotent stem cells has been hampered by the lack of a standardized, quantitative, scalable assay of pluripotency. We previously described an assay called ScoreCard that used gene expression signatures to quantify differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fdca95add842ff21786455a1177df63
https://doi.org/10.1038/nbt.3387
https://doi.org/10.1038/nbt.3387
Autor:
Kendell Clement, Andreas Gnirke, Alexander M. Tsankov, J. Keith Joung, Christina Galonska, Casey A. Gifford, Julie Donaghey, Rahul Karnik, Shengdar Q. Tsai, William Mallard, Veronika Akopian, John L. Rinn, Ramona Pop, Jing Liao, Michael J. Ziller, Hongcang Gu, Alexander Meissner, Deepak Reyon
Publikováno v:
Nature Genetics. 47:469-478
DNA methylation is a key epigenetic modification involved in regulating gene expression and maintaining genomic integrity. Here we inactivated all three catalytically active DNA methyltransferases (DNMTs) in human embryonic stem cells (ESCs) using CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e2b3d4662eb86e213f958cca3f3f2e
https://doi.org/10.1038/ng.3258
https://doi.org/10.1038/ng.3258
Autor:
Hongcang Gu, Alexander Meissner, Alexander M. Tsankov, Veronika Akopian, Andreas Gnirke, Michael J. Ziller, Julie Donaghey, Ido Amit
Publikováno v:
Nature
Summary Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development. Here we report the integrative analysis of genome wide binding data for 38 transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9225f48c995da9bc63136b810eda621c
http://europepmc.org/articles/PMC4499331
http://europepmc.org/articles/PMC4499331
Autor:
Susan Melanie Hawes, David R. Braxton, Catriona McLean, Lydia M. Petrovic, Kouichi Hasegawa, Jun Wu, Kasper S. Wang, Lincon A. Stamp, Veronika Akopian, Parakrama Chandrasoma, Martin F. Pera
Publikováno v:
Stem Cells. 30:1999-2009
Monoclonal antibodies against cell surface markers are powerful tools in the study of tissue regeneration, repair, and neoplasia, but there is a paucity of specific reagents to identify stem and progenitor cells in tissues of endodermal origin. The e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b442f69f5994a475e2723b17d6e8238
https://doi.org/10.1002/stem.1167
https://doi.org/10.1002/stem.1167
Autor:
Hongcang Gu, Alexander Meissner, Bernd Timmermann, Evangelos Kiskinis, Kendell Clement, Andreas Gnirke, Zachary D. Smith, Sven Klages, Michael J. Ziller, Veronika Akopian, Alexander M. Tsankov, Timothy L. Downing, Ramona Pop, Jocelyn Charlton, David Santos
Publikováno v:
Nature Structural and Molecular Biology
Following online publication of this article, the Gene Expression Omnibus records corresponding to accession codes GSM2406773, MN-d6, and GSM2406772, MN-d14, listed in the data availability statement were deleted. The data are now available under acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7062c66ede0357d88816697a72ed41a1
https://doi.org/10.1038/s41594-018-0055-3
https://doi.org/10.1038/s41594-018-0055-3
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells
Autor:
Barbara B. Knowles, Lyn Healy, Outi Hovatta, Steve Oh, Victoria Fox, Nissim Benvenisty, Glyn Stacey, Paul J. Gokhale, Frida Holm, Peter W. Andrews, Veronika Akopian, Ronald D.G. McKay, Janet Rossant, Jennifer L. Brehm, Norio Nakatsuji, Takamichi Miyazaki, Angela Ford, Martin F. Pera, Tenneille Ludwig, Megan Christie, Stephen J. Beil, Hirofumi Suemori
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal
Akopian, V, Andrews, P W, Beil, S, Benvenisty, N, Brehm, J, Christie, M, Ford, A, Fox, V, Gokhale, P J, Healy, L, Holm, F, Hovatta, O, Knowles, B B, Ludwig, T E, McKay, R D G, Miyazaki, T, Nakatsuji, N, Oh, S K W, Pera, M F, Rossant, J & Stacey, G N & Suemori, H 2010, ' Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells ', In Vitro Cellular and Developmental Biology-Animal, vol. 46, no. 3-4, pp. 247-58 . https://doi.org/10.1007/s11626-010-9297-z
Akopian, V, Andrews, P W, Beil, S, Benvenisty, N, Brehm, J, Christie, M, Ford, A, Fox, V, Gokhale, P J, Healy, L, Holm, F, Hovatta, O, Knowles, B B, Ludwig, T E, McKay, R D G, Miyazaki, T, Nakatsuji, N, Oh, S K W, Pera, M F, Rossant, J & Stacey, G N & Suemori, H 2010, ' Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells ', In Vitro Cellular and Developmental Biology-Animal, vol. 46, no. 3-4, pp. 247-58 . https://doi.org/10.1007/s11626-010-9297-z
There are many reports of defined culture systems for the propagation of human embryonic stem cells in the absence of feeder cell support, but no previous study has undertaken a multi-laboratory comparison of these diverse methodologies. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afe235715f0856c60bdaf0ed0138ca8
https://doi.org/10.1007/s11626-010-9297-z
https://doi.org/10.1007/s11626-010-9297-z
Autor:
Zachary D. Smith, Payman Samavarchi-Tehrani, Alexander M. Tsankov, Michael J. Ziller, Kendell Clement, Elizabeth Lehtola, Alexander Meissner, Christina Galonska, Camille Sindhu, Casey A. Gifford, Michelle Chan, Veronika Akopian, Jamie Orme Webster, Yingying Zhang, Jing Liao
Publikováno v:
Genome Biology
A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012. This year's Joint Keystone Symposium on Epigenomics and Chromatin Dynamics was one of the largest Keystone meetings to date, ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ff984bca2894282c5216131f33f51b
https://doi.org/10.1186/gb-2012-13-2-313
https://doi.org/10.1186/gb-2012-13-2-313