Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Veronika, Navrkalova"'
Autor:
Terezia Kurucova, Kamila Reblova, Pavlina Janovska, Jakub Pawel Porc, Veronika Navrkalova, Sarka Pavlova, Jitka Malcikova, Karla Plevova, Boris Tichy, Michael Doubek, Vitezslav Bryja, Jana Kotaskova, Sarka Pospisilova
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2541-2553 (2024)
Early identification of resistant cancer cells is currently a major challenge, as their expansion leads to refractoriness. To capture the dynamics of these cells, we made a comprehensive analysis of disease progression and treatment response in a chr
Externí odkaz:
https://doaj.org/article/c833416f75ab4151874dbe6f3b782ba0
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Autor:
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Kamila Stranska, Michaela Spunarova, Martin Trbusek, Veronika Navrkalova, Barbara Dvorackova, Nikola Tom, Karol Pal, Marie Jarosova, Yvona Brychtova, Anna Panovska, Michael Doubek, Sarka Pospisilova
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Telomeres are protective structures at chromosome ends which shorten gradually with increasing age. In chronic lymphocytic leukemia (CLL), short telomeres have been associated with unfavorable disease outcome, but the link between
Externí odkaz:
https://doaj.org/article/62c7fe3bce37456bb78f5e4434870ef7
Autor:
Tomas Arpas, Hana Jelinkova, Stepan Hrabovsky, Martina Orsulova, Zuzana Vrzalova, Veronika Navrkalova, Eva Brhelova, Lenka Bryjova, Alena Bulikova, Eva Ondrouskova, Marketa Sejnohova, Frantisek Folber, Petra Sedová, Jiri Mayer, Sarka Pospisilova, Marie Jarosova, Michael Doubek
Publikováno v:
Clinical Case Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Near‐haploid acute lymphoblastic leukemia is rare subgroup of the disease, which is very important due to very poor prognosis and resistance to treatment including novel monoclonal antibodies and CAR‐T therapy.
Externí odkaz:
https://doaj.org/article/debb4ebd97ae4864b28c958bd2971d78
Publikováno v:
PeerJ, Vol 9, p e10897 (2021)
Molecular profiling of tumor samples has acquired importance in cancer research, but currently also plays an important role in the clinical management of cancer patients. Rapid identification of genomic aberrations improves diagnosis, prognosis and e
Externí odkaz:
https://doaj.org/article/985b7d86d9a74dc78a9fd38141d7a17b
Autor:
Alexander C. Leeksma, Ingrid A. M. Derks, M. Haidar Kasem, Emine Kilic, Annelies de Klein, Martine J. Jager, Arjan A. van de Loosdrecht, Joop H. Jansen, Veronika Navrkalova, Laura M. Faber, Nadja Zaborsky, Alexander Egle, Thorsten Zenz, Sarka Pospisilova, Omar Abdel-Wahab, Arnon P. Kater, Eric Eldering
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Recurrent mutations in splicing factor 3B subunit 1 (SF3B1) have been identified in several malignancies and are associated with an increased expression of 3’ cryptic transcripts as a result of alternative branchpoint recognition. A large fraction
Externí odkaz:
https://doaj.org/article/91502537fb6b4b8b844b64388f53fc8a
Autor:
Veronika Navrkalova, Emma Young, Panagiotis Baliakas, Lenka Radova, Lesley-Ann Sutton, Karla Plevova, Larry Mansouri, Viktor Ljungström, Stavroula Ntoufa, Zadie Davis, Gunnar Juliusson, Karin E. Smedby, Chrysoula Belessi, Panagiotis Panagiotidis, Tasoula Touloumenidou, Frederic Davi, Anton W. Langerak, Paolo Ghia, Jonathan C. Strefford, David Oscier, Jiri Mayer, Kostas Stamatopoulos, Sarka Pospisilova, Richard Rosenquist, Martin Trbusek
Publikováno v:
Haematologica, Vol 101, Iss 9 (2016)
Externí odkaz:
https://doaj.org/article/c3d075fc37da4bfbbe723124a9af0818
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Externí odkaz:
https://doaj.org/article/8ff49f30f67f4d069249a0ac95eb7402
Autor:
Lesley-Ann Sutton, Viktor Ljungström, Larry Mansouri, Emma Young, Diego Cortese, Veronika Navrkalova, Jitka Malcikova, Alice F. Muggen, Martin Trbusek, Panagiotis Panagiotidis, Frederic Davi, Chrysoula Belessi, Anton W. Langerak, Paolo Ghia, Sarka Pospisilova, Kostas Stamatopoulos, Richard Rosenquist
Publikováno v:
Haematologica, Vol 100, Iss 3 (2015)
Next-generation sequencing has revealed novel recurrent mutations in chronic lymphocytic leukemia, particularly in patients with aggressive disease. Here, we explored targeted re-sequencing as a novel strategy to assess the mutation status of genes w
Externí odkaz:
https://doaj.org/article/32d6b0158569438e91c94271af6b9834
Autor:
Stepan, Hrabovsky, Zuzana, Vrzalova, Jiri, Stika, Hana, Jelinkova, Marie, Jarosova, Veronika, Navrkalova, Jiri, Martenek, Frantisek, Folber, Cyril, Salek, Jan M, Horacek, Sarka, Pospisilova, Jiri, Mayer, Michael, Doubek
Publikováno v:
Acta oncologica (Stockholm, Sweden). 60(6)
We analyzed bone marrow and peripheral blood samples of adult B-other ALL patients treated consecutively at three major Czech teaching hospitals. Samples were analyzed by cytogenetic methods, gene expression profiling, multiplex ligation-dependent pr
Autor:
Veronika Navrkalova, Ludmila Sebejova, Jana Zemanova, Jana Kminkova, Blanka Kubesova, Jitka Malcikova, Marek Mraz, Jana Smardova, Sarka Pavlova, Michael Doubek, Yvona Brychtova, David Potesil, Veronika Nemethova, Jiri Mayer, Sarka Pospisilova, Martin Trbusek
Publikováno v:
Haematologica, Vol 98, Iss 7 (2013)
ATM abnormalities are frequent in chronic lymphocytic leukemia and represent an important prognostic factor. Sole 11q deletion does not result in ATM inactivation by contrast to biallelic defects involving mutations. Therefore, the analysis of ATM mu
Externí odkaz:
https://doaj.org/article/7151e415765547daba8ee5a8ed2e6964