Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions

Autor: Nina Kunová, Gabriela Ondrovičová, Jacob A. Bauer, Veronika Krajčovičová, Matyáš Pinkas, Barbora Stojkovičová, Henrieta Havalová, Veronika Lukáčová, Lenka Kohútová, Július Košťan, Lucia Martináková, Peter Baráth, Jiří Nováček, Sebastian Zoll, Sami Kereϊche, Eva Kutejová, Vladimír Pevala

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Phosphorylation plays a crucial role in the regulation of many fundamental cellular processes. Phosphorylation levels are increased in many cancer cells where they may promote changes in mitochondrial homeostasis. Proteomic studies on variou

Externí odkaz: https://doaj.org/article/5368c6745a034ecba542e4c421929eab

Highly flexible metabolism of the marine euglenozoan protist Diplonema papillatum

Autor: Kristína Záhonová, Peter Barath, Anton Horváth, Ingrid Škodová-Sveráková, Veronika Lukáčová, Anzhelika Butenko, Lenka Kohútová, Julius Lukeš, Aleš Horák, Martin Moos, Galina Prokopchuk, Barbora Bučková, Maksym Danchenko, Valéria Juricová, Petr Šimek, Drahomíra Faktorová

Publikováno v: BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-21 (2021)

Background The phylum Euglenozoa is a group of flagellated protists comprising the diplonemids, euglenids, symbiontids, and kinetoplastids. The diplonemids are highly abundant and speciose, and recent tools have rendered the best studied representati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e943c806a0ec061e8164fa3008f9d9e
https://pubmed.ncbi.nlm.nih.gov/34819072

The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids

Autor: Barbora Keresztesová, Jozef Nosek, Katerina Hanakova, Jan Frankovsky, Katarina Prochazkova, Peter Barath, Jana Bellova, Vladimír Pevala, Veronika Lukáčová, Lubomir Tomaska, Eva Kutejová, Jacob A. Bauer, Gabriela Ondrovičová, Nina Kunová, Nikola Čanigová, Zbynek Zdrahal, Barbara Sivakova

Publikováno v: The Journal of Biological Chemistry

Acylation modifications, such as the succinylation of lysine, are post-translational modifications and a powerful means of regulating protein activity. Some acylations occur nonenzymatically, driven by an increase in the concentration of acyl group d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760fd1f464b73b43d5049deeac5004db
https://doi.org/10.1016/j.jbc.2021.101155

Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.

Autor: Kunová, Nina^1,2 (AUTHOR), Ondrovičová, Gabriela¹ (AUTHOR), Bauer, Jacob A.¹ (AUTHOR), Krajčovičová, Veronika^1,3 (AUTHOR), Pinkas, Matyáš⁴ (AUTHOR), Stojkovičová, Barbora^1,2 (AUTHOR), Havalová, Henrieta¹ (AUTHOR), Lukáčová, Veronika⁵ (AUTHOR), Kohútová, Lenka⁶ (AUTHOR), Košťan, Július⁷ (AUTHOR), Martináková, Lucia¹ (AUTHOR), Baráth, Peter^5,6 (AUTHOR), Nováček, Jiří⁴ (AUTHOR), Zoll, Sebastian⁸ (AUTHOR), Kereϊche, Sami^2,8 (AUTHOR) skere@lf1.cuni.cz, Kutejová, Eva¹ (AUTHOR) eva.kutejova@savba.sk, Pevala, Vladimír¹ (AUTHOR) vladimir.pevala@savba.sk

Publikováno v: Scientific Reports. 4/30/2024, Vol. 14 Issue 1, p1-17. 17p.