Výsledky vyhledávání - "Veronica Travaglione"

Abstract 5045: The Hh inhibitor IPI-926 inhibits relapse of a non-small cell lung cancer xenograft model following treatment with an EGF-R targeted tyrosine kinase inhibitor

Autor: Karen McGovern, John Macdougall, Veronica Travaglione, Margaret Read, Everton Mandley, Kerry White, Kerrie Faia

Publikováno v: Cancer Research. 70:5045-5045

The Hedgehog (Hh) pathway plays a key role in multiple types of cancer, either by mutational activation of the pathway in tumor cells or by ligand-dependent signaling to the tumor cells or paracrine signaling between tumor cells and the tumor microen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a0a1369b3f7b7e2fe61e8dc0dfede89
https://doi.org/10.1158/1538-7445.am10-5045

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Abstract LB-374: The Hh inhibitor IPI-926 enhances tumor perfusion and nab-paclitaxel activity in a pancreatic xenograft model

Autor: David A. Tuveson, Veronica Travaglione, John Macdougall, Martijn P. Lolkema, Anna Trujillo, Karen McGovern, Igor V. Deyneko, Jennifer Proctor

Publikováno v: Cancer Research. 70:LB-374

Malignant activation of the Hedgehog (Hh) pathway is associated with multiple tumor types. In certain cancers, such as pancreatic, a paracrine role for the Hh ligand has been described, wherein cancer cells produce Hh ligand that activates the Hh pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71abd8fd98a2288d64deebc7760f398e
https://doi.org/10.1158/1538-7445.am10-lb-374

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Abstract 3857: Hedgehog signaling in primary prostate tumors and associated metastases

Autor: Jennifer Proctor, Veronica Travaglione, Robert L. Vessella, Margaret Read, John Macdougall, Igor V. Deyneko, Karen McGovern, Robert S. Ross

Publikováno v: Cancer Research. 70:3857-3857

Malignant activation of the Hedgehog (Hh) pathway is associated with multiple tumor types. The Hh pathway can promote growth of certain cancers via three modes of malignant activation: ligand-dependent signaling either to the tumor cell itself or bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d938db9801d1a91c27ece90f3da4008b
https://doi.org/10.1158/1538-7445.am10-3857

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