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pro vyhledávání: '"Veronica S. Hughes"'
Autor:
Veronica S. Hughes, Dietmar W. Siemann
Publikováno v:
Oncotarget
C-Met is a frequently overexpressed or amplified receptor tyrosine kinase involved in metastatic-related functions, including migration, invasion, cell survival, and angiogenesis. Because of its role in cancer progression and metastasis, many inhibit
Autor:
Dietmar W. Siemann, Veronica S. Hughes
Publikováno v:
Trends in Cancer. 4:94-97
The c-Met/HGF pathway is implicated in cancer progression and dissemination. Many inhibitors have been developed to target this pathway. Unfortunately, most trials have failed to demonstrate efficacy. However, clinical trials have not adequately test
Autor:
Henrietta O. Fasanya, Veronica S. Hughes, Samantha S. Dykes, Dietmar W. Siemann, Mai Tanaka, Jennifer M. Wiggins
Publikováno v:
Oncotarget
Breast cancer in the United States is the second most commonly diagnosed cancer in women. About 1 in 8 women will develop invasive breast cancer over the course of her lifetime and breast cancer remains the second leading cause of cancer-related deat
Publikováno v:
Cancer Research. 78:3923-3923
C-Met is a receptor tyrosine kinase critical for embryogenesis and liver repair. In tumors, including breast, prostate, glioblastoma, and thyroid cancer, Met protein levels are often elevated and associated with disease progression and metastasis. Th
Publikováno v:
The British Journal of Radiology. :20170955
In 2012, cancer affected 14.1 million people worldwide and was responsible for 8.2 million deaths. The disease predominantly affects aged populations and is one of the leading causes of death in most western countries. In tumors, the aggressive growt
Autor:
Dietmar W. Siemann, Veronica S. Hughes
Publikováno v:
Tumor and Microenvironment. 1:30
Introduction: The src inhibitor dasatinib has been widely studied as an antimetastatic agent. The aims of this study were to examine the effect of Src inhibition on the metastatic potential of the 4T1 murine mammary carcinoma. Context: Src is a nonre
Autor:
Dietmar W. Siemann, Veronica S. Hughes
Publikováno v:
Cancer Research. 77:3063-3063
Tumor cells frequently harbor abnormalities in signaling pathways, leading to increased migration, invasion, survival, angiogenesis, and proliferation. C-Met is one such commonly aberrant pathway. Because of its effects on tumor cells, c-Met has been
Autor:
Dietmar W. Siemann, Veronica S. Hughes
Publikováno v:
Cancer Research. 76:4102-4102
Tumor cells frequently harbor abnormalities in signaling pathways, leading to increased migration, invasion, survival, angiogenesis, and proliferation. C-Met is a receptor tyrosine kinase critical for embryogenesis and liver repair, and protein level
Autor:
Veronica S. Hughes, Dietmar W. Siemann
Publikováno v:
Cancer Research. 75:4122-4122
Tumor cells frequently harbor abnormalities in signaling pathways, leading to increased migration, invasion, survival, angiogenesis, and proliferation. C-Met is one such commonly aberrant pathway. C-Met is a receptor tyrosine kinase critical for embr