Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Veronica Patton"'
Autor:
Julien A R Amat, Veronica Patton, Caroline Chauché, Daniel Goldfarb, Joanna Crispell, Quan Gu, Alice M Coburn, Gaelle Gonzalez, Daniel Mair, Lily Tong, Luis Martinez-Sobrido, John F Marshall, Francesco Marchesi, Pablo R Murcia
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010174 (2021)
The mechanisms and consequences of genome evolution on viral fitness following host shifts are poorly understood. In addition, viral fitness -the ability of an organism to reproduce and survive- is multifactorial and thus difficult to quantify. Influ
Externí odkaz:
https://doaj.org/article/d4388a31f37248619a07a31af9dee1d1
Autor:
Alessia Casolaro, Josee Golay, Clara Albanese, Roberta Ceruti, Veronica Patton, Sabrina Cribioli, Alice Pezzoni, Marco Losa, Gemma Texido, Ursula Giussani, Francesco Marchesi, Nadia Amboldi, Barbara Valsasina, Silvia Bungaro, Gianni Cazzaniga, Alessandro Rambaldi, Martino Introna, Enrico Pesenti, Rachele Alzani
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58424 (2013)
CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We describe the establishment and characterisation of a novel disseminated model of AML (AML-NS8),
Externí odkaz:
https://doaj.org/article/9ff701b67ac14375b7e6e3ca8f819c84
Autor:
Jürgen Moll, Daniele Fancelli, Enrico Pesenti, Dario Ballinari, Aurelio Marsiglio, Veronica Patton, Cristina Alli, Chiara Soncini, Claudio Arrigoni, Paola Zugnoni, Paola Storici, Luisa Rusconi, Paola Vianello, Maurizio Rocchetti, Gemma Texido, Anna Degrassi, Valter Croci, Laura Gianellini, Paolo Cappella, Maria Laura Giorgini, Roberta Ceruti, Patrizia Carpinelli
Supplementary Fig. S1 from PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad37abd8e1e506016be814b1b51c632
https://doi.org/10.1158/1535-7163.22483142.v1
https://doi.org/10.1158/1535-7163.22483142.v1
Autor:
Marina Ciomei, Ciro Mercurio, Enrico Pesenti, Jurgen Moll, Antonella Isacchi, Arturo Galvani, Francesco Colotta, Fulvia Roletto, Veronica Patton, Wilma Pastori, Giuseppe Locatelli, Francesco Fiorentini, Claudio Festuccia, Maria Gabriella Brasca, Dario Ballinari, Nilla Avanzi, Nadia Amboldi, Rachele Alzani, Clara Albanese
Altered expression and activity of cyclin-dependent kinase (CDK) and tropomyosin receptor kinase (TRK) families are observed in a wide variety of tumors. In those malignancies with aberrant CDK activation, the retinoblastoma protein (pRb) pathway is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bb653415d9936d93679b97e43a99b1
https://doi.org/10.1158/1535-7163.c.6532245.v1
https://doi.org/10.1158/1535-7163.c.6532245.v1
Autor:
Jürgen Moll, Daniele Fancelli, Enrico Pesenti, Dario Ballinari, Aurelio Marsiglio, Veronica Patton, Cristina Alli, Chiara Soncini, Claudio Arrigoni, Paola Zugnoni, Paola Storici, Luisa Rusconi, Paola Vianello, Maurizio Rocchetti, Gemma Texido, Anna Degrassi, Valter Croci, Laura Gianellini, Paolo Cappella, Maria Laura Giorgini, Roberta Ceruti, Patrizia Carpinelli
Supplementary Table S1 from PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c070b33c5aefdf25ed1f037d109f678
https://doi.org/10.1158/1535-7163.22483139.v1
https://doi.org/10.1158/1535-7163.22483139.v1
Autor:
Jürgen Moll, Daniele Fancelli, Enrico Pesenti, Dario Ballinari, Aurelio Marsiglio, Veronica Patton, Cristina Alli, Chiara Soncini, Claudio Arrigoni, Paola Zugnoni, Paola Storici, Luisa Rusconi, Paola Vianello, Maurizio Rocchetti, Gemma Texido, Anna Degrassi, Valter Croci, Laura Gianellini, Paolo Cappella, Maria Laura Giorgini, Roberta Ceruti, Patrizia Carpinelli
PHA-739358 is a small-molecule 3-aminopyrazole derivative with strong activity against Aurora kinases and cross-reactivities with some receptor tyrosine kinases relevant for cancer. PHA-739358 inhibits all Aurora kinase family members and shows a dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb0bde1377ecffa21e6fcbd2a5240d3
https://doi.org/10.1158/1535-7163.c.6531083.v1
https://doi.org/10.1158/1535-7163.c.6531083.v1
Autor:
Sandra Healy, Jürgen Moll, Nilla Avanzi, Clara Albanese, Antonella Ciavolella, Marina Cattoni, Francesco Sola, Pierluigi Tenca, Marcello Tibolla, Veronica Patton, Dario Ballinari, Sonia Rainoldi, Alessia Montagnoli, Enrico Pesenti, Rachele Alzani, Aaron Bensimon, Antonella Isacchi, Maria Menichincheri, Ermes Vanotti, Vanessa Marchesi, Deborah Brotherton, Francesco Fiorentini, Daniele Volpi, Barbara Valsasina, Corrado Santocanale, Antonio Molinari, Valter Croci
Publikováno v:
Nature Chemical Biology. 4:357-365
Cdc7 is an essential kinase that promotes DNA replication by activating origins of replication. Here, we characterized the potent Cdc7 inhibitor PHA-767491 (1) in biochemical and cell-based assays, and we tested its antitumor activity in rodents. We
Autor:
Giulia Taraboletti, Robert Fruscio, Alessandra Decio, Raffaella Giavazzi, Rachele Alzani, Juliane M. Jürgensmeier, Patrizia Perego, Dorina Belotti, Veronica Patton
Vascular endothelial growth factor C (VEGFC) has been reported to promote tumor progression in several tumor types, mainly through the stimulation of lymphangiogenesis and lymphatic metastasis. However, the expression and biological significance of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e92007458976ab418984b9884f7650
http://hdl.handle.net/10281/53301
http://hdl.handle.net/10281/53301
Autor:
Wilma Pastori, Simona Bindi, Daniele Casero, Marina Ciomei, Sabrina Cribioli, Nadia Amboldi, Cinzia Pellizzoni, Paola Gnocchi, Nilla Avanzi, Daniele Donati, Elena Ardini, Giulia Canevari, Gemma Texido, Arturo Galvani, Marcella Nesi, Maria Gabriella Brasca, Eduard R. Felder, Antonella Isacchi, Cinzia Cristiani, Roberta Ceruti, Veronica Patton
Publikováno v:
Molecular Cancer Therapeutics. 14:A179-A179
The Janus Kinases (JAK1, JAK2, JAK3, TYK2) are non-receptor tyrosine kinases that play important roles in hematopoiesis and immune response. In particular, gene ablation of JAK1 or JAK2 in the mouse is incompatible with life, due to neurological defe
Autor:
Ulisse, Cucchi, Laura M, Gianellini, Anna, De Ponti, Francesco, Sola, Rachele, Alzani, Veronica, Patton, Alice, Pezzoni, Sonia, Troiani, Maria B, Saccardo, Simona, Rizzi, Maria L, Giorgini, Paolo, Cappella, Italo, Beria, Barbara, Valsasina
Publikováno v:
Anticancer research. 30(12)
Polo-like kinase 1 (PLK1) is the master regulator of mitosis and a target for anticancer therapy. To develop a marker of PLK1 activity in cells and tumour tissues, this study focused on translational controlled tumour protein (TCTP) and identified se