NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol

Autor: Veronica Panichi, Irene Bissoli, Stefania D’Adamo, Flavio Flamigni, Silvia Cetrullo, Rosa Maria Borzì

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 6, p 5830 (2023)

Osteoarthritis (OA) is the most common joint disease, but no effective and safe disease-modifying treatment is available. Risk factors such as age, sex, genetics, injuries and obesity can concur to the onset of the disease, variably triggering the lo

Externí odkaz: https://doaj.org/article/d21b52781637410d961035e316a7dd3f

Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes

Autor: Manuela Minguzzi, Veronica Panichi, Stefania D’Adamo, Silvia Cetrullo, Luca Cattini, Flavio Flamigni, Erminia Mariani, Rosa Maria Borzì

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 21, p 12012 (2021)

Notch signaling has been identified as a critical regulator of cartilage development and homeostasis. Its pivotal role was established by both several joint specific Notch signaling loss of function mouse models and transient or sustained overexpress

Externí odkaz: https://doaj.org/article/5a358195dec846698abc8316bc227970

Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids

Autor: Silvia Cetrullo, Stefania D’Adamo, Veronica Panichi, Rosa Maria Borzì, Carla Pignatti, Flavio Flamigni

Publikováno v: Cells, Vol 9, Iss 3, p 537 (2020)

While high levels of saturated fatty acids are associated with impairment of cardiovascular functions, n-3 polyunsaturated fatty acids (PUFAs) have been shown to exert protective effects. However the molecular mechanisms underlying this evidence are

Externí odkaz: https://doaj.org/article/13bd2dbaf2074b669b4247a316174547

Nutraceutical supplementation modulates autophagy and fibril deposition in primary chondrocytes

Autor: Stefania D'Adamo, Silvia Cetrullo, Veronica Panichi, Irene Bissoli, Erminia Mariani, Flavio Flamigni, Rosa Maria Borzì

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::86b71cf01fec0d69839c144de2dc7ce7
http://hdl.handle.net/11585/834085

Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes

Autor: Luca Cattini, Silvia Cetrullo, Flavio Flamigni, Stefania D'Adamo, Veronica Panichi, Manuela Minguzzi, Rosa Maria Borzì, Erminia Mariani

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 12012, p 12012 (2021)

Notch signaling has been identified as a critical regulator of cartilage development and homeostasis. Its pivotal role was established by both several joint specific Notch signaling loss of function mouse models and transient or sustained overexpress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719a7e3bb0fc5786c3e366c6cbc71966
https://doi.org/10.3390/ijms222112012