Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Veronica Olivo Pimentel"'
1
Akademický článek
Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy
Autor: Veronica Olivo Pimentel, Damiënne Marcus, Alexander MA van der Wiel, Natasja G Lieuwes, Rianne Biemans, Relinde IY Lieverse, Dario Neri, Jan Theys, Ala Yaromina, Ludwig J Dubois, Philippe Lambin
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Poorly immunogenic tumors are hardly responsive to immunotherapies such as immune checkpoint blockade (ICB) and are, therefore, a therapeutic challenge. Combination with other immunotherapies and/or immunogenic therapies, such as radiother
Externí odkaz: https://doaj.org/article/79cc56a05cf2418c8eb72e923bf9ce7a
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2
Akademický článek
Critical Contribution of NK Group 2 Member D Expressed on Invariant Natural Killer T Cells in Concanavalin A-Induced Liver Hepatitis in Mice
Autor: Dina Al Dulaimi, Jihene Klibi, Veronica Olivo Pimentel, Veronique Parietti, Matthieu Allez, Antoine Toubert, Kamel Benlagha
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Natural killer group 2D (NKG2D) is a well-characterized activating receptor expressed on many immune cells, including invariant natural killer T (iNKT) cells. These cells were shown to be responsible of liver injury in the model of concanavalin A (Co
Externí odkaz: https://doaj.org/article/f8049fd453884107a5023bd80937c703
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3
Akademický článek
The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses
Autor: Nicolle H. Rekers, Veronica Olivo Pimentel, Ala Yaromina, Natasja G. Lieuwes, Rianne Biemans, Catharina M. L. Zegers, Wilfred T. V. Germeraad, Evert J. Van Limbergen, Dario Neri, Ludwig J. Dubois, Philippe Lambin
Publikováno v: OncoImmunology, Vol 7, Iss 4 (2018)
Recently, we have shown that the administration of the tumour-targeted antibody-based immunocytokine L19-IL2 after radiotherapy (RT) resulted in synergistic anti-tumour effect. Here we show that RT and L19-IL2 can activate a curative abscopal effect,
Externí odkaz: https://doaj.org/article/371eb8000c2f4cfaa75cfee345c249c1
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4
Akademický článek
HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells
Autor: Eloy Moreno Roig, Arjan J. Groot, Ala Yaromina, Tessa C. Hendrickx, Lydie M. O. Barbeau, Lorena Giuranno, Glenn Dams, Jonathan Ient, Veronica Olivo Pimentel, Marike W. van Gisbergen, Ludwig J. Dubois, Marc A. Vooijs
Publikováno v: Cells, Vol 8, Iss 1, p 45 (2019)
The hypoxia-inducible transcription factors (HIF)-1/2α are the main oxygen sensors which regulate the adaptation to intratumoral hypoxia. The aim of this study was to assess the role of the HIF proteins in regulating the radiation response of a non-
Externí odkaz: https://doaj.org/article/a57a3bc6fa54419b86f08b433c6861ca
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5
Children and adults with mild COVID-19 symptoms develop memory T cell immunity to SARS-CoV-2
Autor: Nynke Y. Rots, Martien C. M. Poelen, Veronica Olivo Pimentel, Maarten E. Emmelot, Jelle de Wit, Daphne F.M. Reukers, Cecile A C M van Els, Adam Meijer, Josine van Beek, Lisa Beckers, Rutger M. Schepp, Alper Cevirgel, Patricia Kaaijk, Gerco den Hartog
BackgroundSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to considerable morbidity/mortality worldwide, but most infections, especially among children, have a mild course. However, it remains largely unknown whether infected chi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e97b8075c3e6d37a06d8dd993af376f4
https://doi.org/10.1101/2021.09.10.21263333
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6
Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy
Autor: Ludwig Dubois, Jan Theys, Dario Neri, Natasja G. Lieuwes, Alexander M A van der Wiel, Ala Yaromina, R. Biemans, Veronica Olivo Pimentel, Relinde I Y Lieverse, Philippe Lambin, Damiënne Marcus
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for ImmunoTherapy of Cancer, 9 (3)
Journal for ImmunoTherapy of Cancer, 9(3):001764. BioMed Central Ltd
Journal for ImmunoTherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundPoorly immunogenic tumors are hardly responsive to immunotherapies such as immune checkpoint blockade (ICB) and are, therefore, a therapeutic challenge. Combination with other immunotherapies and/or immunogenic therapies, such as radiothera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae4375d17de5a2aca6741c0b19a0e56
https://jitc.bmj.com/content/9/3/e001764.full
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7
A novel co-culture assay to assess anti-tumor CD8+ T cell cytotoxicity via luminescence and multicolor flow cytometry
Autor: Ludwig Dubois, Ala Yaromina, Veronica Olivo Pimentel, Philippe Lambin, Damiënne Marcus
Publikováno v: Journal of Immunological Methods
Journal of Immunological Methods, 487:112899. Elsevier Science
T cell immunotherapies have shown great promise in patients with advanced cancer disease, revolutionizing treatment. T cell cytotoxicity is crucial in its efficacy, therefore developing ex vivo methods testing tumor and T cell interactions is pivotal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326b061a928d9fbe819efb9ccf5223b6
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8
HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells
Autor: Glenn Dams, Marc Vooijs, Ala Yaromina, Marike W. van Gisbergen, Arjan J. Groot, Lydie M. O. Barbeau, Jonathan Ient, Eloy Moreno Roig, Veronica Olivo Pimentel, Ludwig Dubois, Lorena Giuranno, Tessa C. Hendrickx
Publikováno v: Cells, Vol 8, Iss 1, p 45 (2019)
Cells
Volume 8
Issue 1
Cells, 8(1):45. Multidisciplinary Digital Publishing Institute (MDPI)
The hypoxia-inducible transcription factors (HIF)-1/2&alpha
are the main oxygen sensors which regulate the adaptation to intratumoral hypoxia. The aim of this study was to assess the role of the HIF proteins in regulating the radiation response
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de4a491f72775db7c6014cf3aed1c80
http://www.mdpi.com/2073-4409/8/1/45
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9
The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses
Autor: Ludwig Dubois, Catharina M.L. Zegers, Evert J. Van Limbergen, Nicolle H. Rekers, Ala Yaromina, Veronica Olivo Pimentel, Dario Neri, R. Biemans, Wilfred T. V. Germeraad, Natasja G. Lieuwes, Philippe Lambin
Publikováno v: OncoImmunology, 7 (14)
Oncoimmunology
OncoImmunology
OncoImmunology, Vol 7, Iss 4 (2018)
OncoImmunology, 7(4):e1414119. Landes Bioscience
Recently, we have shown that the administration of the tumour-targeted antibody-based immunocytokine L19-IL2 after radiotherapy (RT) resulted in synergistic anti-tumour effect. Here we show that RT and L19-IL2 can activate a curative abscopal effect,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1af75ba4057815196cbc5908225ac9
https://hdl.handle.net/20.500.11850/238558
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10
IL2 based immunotherapies: towards a personalized and curative antitumor response
Autor: Nicolle H. Rekers, Ludwig Dubois, Philippe Lambin, Veronica Olivo Pimentel, Ala Yaromina
Publikováno v: Translational Cancer Research, 5(Suppl 6), S1292-S1294. AME Publishing Company
In his commentary, Claus Garbe described our study on the combination of radiotherapy (RT) and the immunocytokine L19-IL2 in the F9 fibrosarcoma model (1) and discussed our work in a checkpoint inhibitor related context. The author is positioning int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3959bd0a622f0291f9a5b230406c3cd9
https://doi.org/10.21037/tcr.2016.11.26
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