Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Veronica Marabitti"'
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107382- (2024)
It is now recognized that tumors are not merely masses of transformed cells but are intricately interconnected with healthy cells in the tumor microenvironment (TME), forming complex and heterogeneous structures. Recent studies discovered that cancer
Externí odkaz:
https://doaj.org/article/36c5eaf0671d4f138254c154270691d6
Publikováno v:
eLife, Vol 12 (2024)
R-loops are non-canonical DNA structures that form during transcription and play diverse roles in various physiological processes. Disruption of R-loop homeostasis can lead to genomic instability and replication impairment, contributing to several hu
Externí odkaz:
https://doaj.org/article/b8e1699c4ee14225866a0af417da4a8f
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-5 (2023)
Abstract The term “metastatic cascade” defines a process whereby few tumor cells complete a sequence of steps to leave the primary tumor to reach one or more sites elsewhere in the body, usually through the bloodstream to develop one or several m
Externí odkaz:
https://doaj.org/article/4d07fb1161ac4bcf89531b6d859386e6
Autor:
Consuelo Pitolli, Alberto Marini, Marika Guerra, Marco Pieraccioli, Veronica Marabitti, Fernando Palluzzi, Luciano Giacò, Gianpiero Tamburrini, Francesco Cecconi, Francesca Nazio, Claudio Sette, Vittoria Pagliarini
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Medulloblastoma (MB) is the most common cerebellar malignancy during childhood. Among MB, MYC-amplified Group 3 tumors display the worst prognosis. MYC is an oncogenic transcription factor currently thought to be undruggable. Neve
Externí odkaz:
https://doaj.org/article/030743204b074a1299f471eeca329a4b
Autor:
Illari Salvatori, Valentina Nesci, Alida Spalloni, Veronica Marabitti, Maurizio Muzzi, Henri Zenuni, Silvia Scaricamazza, Marco Rosina, Gianmarco Fenili, Mariangela Goglia, Laura Boffa, Roberto Massa, Sandra Moreno, Nicola Biagio Mercuri, Francesca Nazio, Patrizia Longone, Alberto Ferri, Cristiana Valle
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3251 (2024)
Amyotrophic Lateral Sclerosis (ALS) is considered the prototype of motor neuron disease, characterized by motor neuron loss and muscle waste. A well-established pathogenic hallmark of ALS is mitochondrial failure, leading to bioenergetic deficits. So
Externí odkaz:
https://doaj.org/article/0f689b9b5fad4ddcbc4869bc4873aaeb
Autor:
Veronica Marabitti, Manuela Giansanti, Francesca De Mitri, Francesca Gatto, Angela Mastronuzzi, Francesca Nazio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Tumor-specific alterations in metabolism have been recognized to sustain the production of ATP and macromolecules needed for cell growth, division and survival in many cancer types. However, metabolic heterogeneity poses a challenge for the establish
Externí odkaz:
https://doaj.org/article/5ee87f2e4d2940b8b93038a46caacafd
Autor:
Eva Malacaria, Giusj Monia Pugliese, Masayoshi Honda, Veronica Marabitti, Francesca Antonella Aiello, Maria Spies, Annapaola Franchitto, Pietro Pichierri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.
Externí odkaz:
https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c
Autor:
Veronica Marabitti, Pasquale Valenzisi, Giorgia Lillo, Eva Malacaria, Valentina Palermo, Pietro Pichierri, Annapaola Franchitto
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1547 (2022)
Maintenance of genome stability is crucial for cell survival and relies on accurate DNA replication. However, replication fork progression is under constant attack from different exogenous and endogenous factors that can give rise to replication stre
Externí odkaz:
https://doaj.org/article/3cce765f2af74f9690d7512038949d48
Autor:
Giusj Monia Pugliese, Federico Salaris, Valentina Palermo, Veronica Marabitti, Nicolò Morina, Alessandro Rosa, Annapaola Franchitto, Pietro Pichierri
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Schimke immuno-osseous dysplasia is an autosomal recessive genetic osteochondrodysplasia characterized by dysmorphism, spondyloepiphyseal dysplasia, nephrotic syndrome and frequently T cell immunodeficiency. Several hypotheses have been proposed to e
Externí odkaz:
https://doaj.org/article/68c1e899dfb5417e8d0ffdd51baae21f
Autor:
Eva Malacaria, Giusj Monia Pugliese, Masayoshi Honda, Veronica Marabitti, Francesca Antonella Aiello, Maria Spies, Annapaola Franchitto, Pietro Pichierri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in Fig. 2. The immunofluorescence images in panel d were inadvertently replaced with duplicates of those in panel c during final assembly of the figure. This has been corrected in the PDF and HT
Externí odkaz:
https://doaj.org/article/331c2beb9414445aacd05b93cdbbdf6b