Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Veronica L. Hall"'
Publikováno v:
Antibiotics, Vol 11, Iss 1, p 104 (2022)
Antimicrobial resistance (AMR) is a concerning global threat that, if not addressed, could lead to increases in morbidity and mortality, coupled with societal and financial burdens. The emergence of AMR bacteria can be attributed, in part, to the dec
Externí odkaz:
https://doaj.org/article/fffcaefa1698492f8ab5e53fe71bda3e
Autor:
Arthur A. Hurwitz, Renata Mazzucchelli, Scott K. Durum, Jami Willette-Brown, Julie A. Hixon, Wenqing Li, Warren J. Leonard, Veronica L. Hall, Rosanne Spolski, Xin Chen
Publikováno v:
Blood. 112:3283-3292
Interleukin-7 (IL-7), a cytokine produced by stromal cells, is required for thymic development and peripheral homeostasis of most major subsets of T cells. We examined whether regulatory T (Treg) cells also required the IL-7 pathway by analyzing IL-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd3e6372e9f6b5e64240e2b2b1c245f
https://doi.org/10.1182/blood-2008-02-137414
https://doi.org/10.1182/blood-2008-02-137414
Publikováno v:
Cancer Research. 66:11005-11012
The use of interleukin-18 (IL-18) together with IL-12 induced high levels of IFN-γ in tumor-bearing mice and regression of liver tumors that was abolished in IFN-γ(−/−) mice. Natural killer (NK) and NKT cells were the major producers of IFN-γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70341a6e26f89357fc948a9472bb813
https://doi.org/10.1158/0008-5472.can-06-0811
https://doi.org/10.1158/0008-5472.can-06-0811
Autor:
Timothy A. Chan, Anthony J. Scarzello, Deborah L. Hodge, Jeff J. Subleski, Veronica L. Hall, Thomas B. Wolfe, Robert H. Wiltrout, Timothy C. Back, John R. Ortaldo, Jonathan M. Weiss
The fate of invariant NKT (iNKT) cells following activation remains controversial and unclear. We systemically examined how iNKT cells are regulated following TCR-dependent and -independent activation with α-galactosylceramide (αGC) or IL-18 plus I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343fed48a0f24e4c56f01c649fe98a22
https://europepmc.org/articles/PMC3725575/
https://europepmc.org/articles/PMC3725575/
Autor:
Faruk Sheikh, Ana M. Gamero, Raymond P. Donnelly, Hsiang-Wen Wang, Anthony J. Scarzello, Håkan C. Steen, Ana L. Romero-Weaver, Veronica L. Hall
Publikováno v:
Molecular cancer research : MCR. 8(1)
Type I IFNs (IFN-α/β) are pleitropic cytokines widely used in the treatment of certain malignancies, hepatitis B and C, and multiple sclerosis. IFN resistance is a challenging clinical problem to overcome. Hence, understanding the molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be582a65b59e59d10b2bc83e97ae91d
https://pubmed.ncbi.nlm.nih.gov/20068068
https://pubmed.ncbi.nlm.nih.gov/20068068
Autor:
Veronica L. Hall, Timothy C. Back, Dejan Micic, Jeff J. Subleski, Xin Chen, Jonathan M. Weiss, Robert H. Wiltrout, William J. Murphy, Jimmy K. Stauffer, Anthony J. Scarzello, Kory Alderson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(46)
Treatment of mice bearing orthotopic, metastatic tumors with anti-CD40 antibody resulted in only partial, transient anti-tumor effects whereas combined treatment with IL-2/anti-CD40, induced tumor regression. The mechanisms for these divergent anti-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c211ec852715159fdd3cb235406552
https://pubmed.ncbi.nlm.nih.gov/19892741
https://pubmed.ncbi.nlm.nih.gov/19892741
Autor:
Jeff J Subleski, Veronica L Hall, Anthony J Scarzello, Thomas B Wolfe, John R Ortaldo, Deborah L Hodge, Jon M Weiss, Tim Chan, Robert H Wiltrout
Publikováno v:
The Journal of Immunology. 182:134.24-134.24
We previously showed that IL-18/IL-12 treatment of tumor bearing mice elicited significant anti-tumor activity concurrent with a decrease in the detectable number of invariant NKT (iNKT) cells. We now demonstrate that acute treatment with IL-18/IL-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c29cd431dade91be509f6d6682087c7
https://doi.org/10.4049/jimmunol.182.supp.134.24
https://doi.org/10.4049/jimmunol.182.supp.134.24
Publikováno v:
The Journal of Immunology. 178:S193-S193
IL-18 + IL-12 treatment elicited significant antitumor activity in the liver via an increase in NK cells and a concurrent decrease in the detectable number of NKT cells. To determine both the fate of NKT cells and the origins of NK influx into the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd53c1eb84f2f58f769e4b33e18739c5
https://doi.org/10.4049/jimmunol.178.supp.98.9
https://doi.org/10.4049/jimmunol.178.supp.98.9
Autor:
Veronica L Hall, Jeff Subleski, Tim C Back, M. Eilene Gruys, Lynnette Shorts-Cary, Jonathan M. Weiss, Robert H Wiltrout
Publikováno v:
The Journal of Immunology. 178:S81-S81
Several immunotherapeutic models have shown that interferon gamma (IFNγ) is required for tumor regression. Treatment with IFNγ as a sole therapy, however, has resulted in disappointing outcomes. Cytokine therapies, such as IL-2/IL-12 and IL-12/IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac0ce698f68d6f092934db9bfd6c6e9
https://doi.org/10.4049/jimmunol.178.supp.48.34
https://doi.org/10.4049/jimmunol.178.supp.48.34