Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Veronica H. Ryan"'
Autor:
Sahba Seddighi, Yue A. Qi, Anna-Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E. Hill, James Hawrot, Daniel M. Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I. Shah, Mike A. Nalls, Jenn Colon-Mercado, Joel F. Reyes, Veronica H. Ryan, Matthew P. Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn Oskarsson, Nathan Staff, Duc M. Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D. Glass, Alessandro Ori, Nicholas T. Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael E. Ward
Publikováno v:
bioRxiv
Functional loss of TDP-43, an RNA-binding protein genetically and pathologically linked to ALS and FTD, leads to inclusion of cryptic exons in hundreds of transcripts during disease. Cryptic exons can promote degradation of affected transcripts, dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52de4bfdb559430326ffc82718aa6b2a
https://europepmc.org/articles/PMC9900763/
https://europepmc.org/articles/PMC9900763/
Autor:
Scott Watters, Balabhadra Khatiwada, Nicolas L. Fawzi, Vincenzo Venditti, Mandar T. Naik, Joshua Amaya, Veronica H Ryan
Publikováno v:
Nucleic Acids Research
hnRNPA2 is a major component of mRNA transport granules in oligodendrocytes and neurons. However, the structural details of how hnRNPA2 binds the A2 recognition element (A2RE) and if this sequence stimulates granule formation by enhancing phase separ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9d6ec3cf3c335c6d2d4de82dd2dd59
http://europepmc.org/articles/PMC7544213
http://europepmc.org/articles/PMC7544213
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132675 (2015)
Phosphoinositides, lipid-signaling molecules, participate in diverse brain processes within a wide metabolic cascade.Gene transcriptional networks coordinately regulate the phosphoinositide cascade during human brain Development and Aging.We used the
Externí odkaz:
https://doaj.org/article/009a9046770a4d68aea5aeecd2f6c77a
Autor:
Veronica H Ryan, Nicolas L. Fawzi
Publikováno v:
Trends Neurosci
Neurons require unique subcellular compartmentalization to function efficiently. Formed from proteins and RNAs through liquid-liquid phase separation, membraneless organelles have emerged as one way in which cells form distinct, specialized compartme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba147fb1635f979ab60a7de4bf5cb46
https://doi.org/10.1016/j.tins.2019.08.005
https://doi.org/10.1016/j.tins.2019.08.005
Autor:
Veronica H Ryan, Christopher T Primiani, Jagadeesh S Rao, Kwangmi Ahn, Stanley I Rapoport, Helene Blanchard
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100858 (2014)
The polyunsaturated arachidonic and docosahexaenoic acids (AA and DHA) participate in cell membrane synthesis during neurodevelopment, neuroplasticity, and neurotransmission throughout life. Each is metabolized via coupled enzymatic reactions within
Externí odkaz:
https://doaj.org/article/13edbb7310bf47f584e52ba8189885e9
Autor:
Christopher T Primiani, Veronica H Ryan, Jagadeesh S Rao, Margaret C Cam, Kwangmi Ahn, Hiren R Modi, Stanley I Rapoport
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110972 (2014)
BACKGROUND:Age changes in expression of inflammatory, synaptic, and neurotrophic genes are not well characterized during human brain development and senescence. Knowing these changes may elucidate structural, metabolic, and functional brain processes
Externí odkaz:
https://doaj.org/article/8765b6f04a7e47c7845c4b40f654f11c
Publikováno v:
Journal of Biological Chemistry. 293:19522-19531
Liquid–liquid phase separation of proteins and nucleic acids into membraneless organelles (MLOs) spatially organizes cellular components and reactions. The RNA-binding protein heterogeneous nuclear ribonucleoprotein A2 (hnRNPA2) carries mRNA target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c4ac1b3863982a96c089ee17a6a381
https://doi.org/10.1074/jbc.ra118.005120
https://doi.org/10.1074/jbc.ra118.005120
Autor:
Camillo F Saueressig, Jeetain Mittal, Gregory L. Dignon, Nicolas L. Fawzi, Theodora Myrto Perdikari, Mandar T. Naik, Veronica H Ryan, Anne C. Hart, Jeremy Lins
Publikováno v:
The EMBO Journal
mRNA transport in neurons requires formation of transport granules containing many protein components, and subsequent alterations in phosphorylation status can release transcripts for translation. Further, mutations in a structurally disordered domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743bf9455975e58a47592183f7790502
https://doi.org/10.15252/embj.2020105001
https://doi.org/10.15252/embj.2020105001
Autor:
Veronica H Ryan, Anastasia C Murthy, Scott Watters, Mandar T. Naik, Nicolas L. Fawzi, Theodora Myrto Perdikari
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of viruses and may assemble within viral factories, dynamic compartments formed within the host cells. Here, we examine the possibility that the multivalent RNA-binding nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d3d7f31a367b0239e63a3d4b69611f
https://doi.org/10.15252/embj.2020106478
https://doi.org/10.15252/embj.2020106478
Autor:
Ilya J. Finkelstein, Mae I. Staples, Corey Frazer, Richard J. Bennett, Veronica H Ryan, Maureen A. Dowell, Nicole V. Johnson, Yoori Kim, Matthew P. Hirakawa, Aaron D Hernday, Nicolas L. Fawzi
Publikováno v:
Nature microbiology, vol 5, iss 11
Nature microbiology
Nature microbiology
Cell identity in eukaryotes is controlled by transcriptional regulatory networks that define cell-type-specific gene expression. In the opportunistic fungal pathogen Candida albicans, transcriptional regulatory networks regulate epigenetic switching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625f63980072ab91818728d8dfb80173
https://escholarship.org/uc/item/6657t24r
https://escholarship.org/uc/item/6657t24r