Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Veronica Fagerholm"'
Autor:
Kim Eerola, Francesca Marchisella, Benjamin D. Peterson, Patrik Hollos, Natalia Kulesskaya, Eleanor T. Coffey, Sylvia Ortega-Martínez, Hasan Mohammad, Emilia Komulainen, H van Praag, Erika Freemantle, E Savontous, Heikki Rauvala, Veronica Fagerholm
Publikováno v:
Molecular Psychiatry
Promoting adult hippocampal neurogenesis is expected to induce neuroplastic changes that improve mood and alleviate anxiety. However, the underlying mechanisms remain largely unknown and the hypothesis itself is controversial. Here we show that mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543e8e31fc641774e7bf661ea32219fc
http://hdl.handle.net/10138/233496
http://hdl.handle.net/10138/233496
Autor:
Pirjo Nuutila, Juhani Knuuti, Tommi Vähäsilta, Patricia Iozzo, Christoffer Stark, Henri Honka, Miikka Tarkia, Minna Soinio, J. Mäkinen, Vesa Oikonen, Amalia Gastaldelli, Antti Saraste, Jarna C. Hannukainen, Tamiko Ishizu, Paulina Salminen, Anna K. Kirjavainen, Mika Teräs, Veronica Fagerholm
Publikováno v:
Diabetologia. 56:893-900
The role of the intestine in the pathogenesis of metabolic diseases is gaining much attention. We therefore sought to validate, using an animal model, the use of positron emission tomography (PET) in the estimation of intestinal glucose uptake (GU),
Autor:
Joern Schlesinger, Tamiko Ishizu, Johan Rajander, Veronica Fagerholm, Kirsi Mikkola, Viki-Veikko Elomaa, Cheng-Bin Yim, Olof Solin, Pirjo Nuutila, Anne Roivainen
Publikováno v:
Nuclear Medicine and Biology; Vol 40
Introduction Renal localization of high radioactivity levels during targeted imaging compromises tissue visualization in the kidney region and limits diagnostic accuracy. Radioiodinated antibody fragments with a renal enzyme-cleavable N e -maleoyl-l-
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 108:365-370
The α(2A)-adrenoceptor has been identified as an important regulator of blood glucose homeostasis. α(2A)-Adrenoceptors on pancreatic β-cells inhibit insulin secretion, and α(2A)-adrenoceptors on sympathetic nerves and on adrenomedullary chromaffi
Autor:
Veronica Fagerholm, K. Någren, Saila Kauhanen, Eveliina Arponen, Pirjo Nuutila, Olof Solin, Kirsi Mikkola, Merja Haaparanta, Tamiko Ishizu
Publikováno v:
Journal of Nuclear Medicine; Vol 51
Journal of Nuclear Medicine
Journal of Nuclear Medicine
Vesicular monoamine transporter 2 (VMAT2) is a putative molecular target for the quantitative imaging of pancreatic beta-cell mass by PET. The VMAT2 PET tracer (11)C-dihydrotetrabenazine ((11)C-DTBZ) exhibits high pancreatic uptake that is reduced in
Autor:
Jarmo Hietala, Erkki Tupala, Jukka Sallinen, Leena Nyman, Johanna Rokka, Jari Tiihonen, Veronica Fagerholm, Merja Haaparanta
Publikováno v:
Synapse. 62:508-515
Indirect experimental evidence suggests that drugs acting on the alpha(2C)-adrenoceptor could be useful in the treatment of neuropsychiatric disorders such as depression and schizophrenia. In rodent brain, the highest levels of alpha(2C)-adrenoceptor
Publikováno v:
European Journal of Pharmacology. 578:359-364
Alpha(2)-Adrenoceptors regulate insulin secretion and sympathetic output. In the present study, alpha(2A)-adrenoceptor knockout (alpha(2A)-KO) mice and their C57BL/6J wild-type (WT) controls were used to assess the glucoregulatory role of the alpha(2
Autor:
Mika Scheinin, Brian K. Kobilka, Jukka Sallinen, Janne Lähdesmäki, Ewen MacDonald, Veronica Fagerholm
Publikováno v:
Neuroscience. 113:289-299
Genetic manipulation of mice now provides new tools to evaluate the biological functions of the alpha(2)-adrenergic receptor (alpha(2)-AR) subtypes (alpha(2A), alpha(2B), and alpha(2C)). To investigate the role of the alpha(2A)-AR in the modulation o
Autor:
Mikkola, Kirsi, Kirsi, Mikkola, Yim, Cheng-Bin, Cheng-Bin, Yim, Fagerholm, Veronica, Veronica, Fagerholm, Ishizu, Tamiko, Tamiko, Ishizu, Elomaa, Viki-Veikko, Viki-Veikko, Elomaa, Rajander, Johan, Johan, Rajander, Jurttila, Jori, Jori, Jurttila, Saanijoki, Tiina, Tiina, Saanijoki, Tolvanen, Tuula, Tuula, Tolvanen, Tirri, Marko, Marko, Tirri, Gourni, Eleni, Eleni, Gourni, Béhé, Martin, Martin, Béhé, Gotthardt, Martin, Martin, Gotthardt, Reubi, Jean Claude, Reubi, Jean-Claude, Mäcke, Helmut, Helmut, Mäcke, Roivainen, Anne, Anne, Roivainen, Solin, Olof, Olof, Solin, Nuutila, Pirjo, Pirjo, Nuutila
Publikováno v:
Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu-and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2
Molecular Imaging and Biology; Vol 16
Molecular Imaging and Biology, 16, 255-63
Molecular Imaging and Biology, 16, 2, pp. 255-63
Molecular Imaging and Biology; Vol 16
Molecular Imaging and Biology, 16, 255-63
Molecular Imaging and Biology, 16, 2, pp. 255-63
Item does not contain fulltext PURPOSE: Glucagon-like peptide-1 receptor (GLP-1R) is a molecular target for imaging of pancreatic beta cells. We compared the ability of [Nle(14),Lys(40)(Ahx-NODAGA-(64)Cu)NH2]-exendin-4 ([(64)Cu]NODAGA-exendin-4) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cace5c97a528b97d294f03e978abaa4
https://boris.unibe.ch/52039/1/s11307-013-0691-2.pdf
https://boris.unibe.ch/52039/1/s11307-013-0691-2.pdf
Autor:
Kirsi Mikkola, Cheng-Bin Yim, Veronica Fagerholm, Tamiko Ishizu, Viki-Veikko Elomaa, Johan Rajander, Jori Jurttila, Tiina Saanijoki, Tuula Tolvanen, Marko Tirri, Eleni Gourni, Martin Béhé, Martin Gotthardt, Jean Claude Reubi, Helmut Mäcke, Anne Roivainen, Olof Solin, Pirjo Nuutila
Publikováno v:
Mikkola, Kirsi; Yim, Cheng-Bin; Fagerholm, Veronica; Ishizu, Tamiko; Elomaa, Viki-Veikko; Rajander, Johan; Jurttila, Jori; Saanijoki, Tiina; Tolvanen, Tuula; Tirri, Marko; Gourni, Eleni; Béhé, Martin; Gotthardt, Martin; Reubi, Jean-Claude; Mäcke, Helmut; Roivainen, Anne; Solin, Olof; Nuutila, Pirjo (2014). Erratum to: (64)Cu-and (68)Ga-Labelled [Nle (14),Lys (40)(Ahx-NODAGA)NH 2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats. Molecular imaging and biology, 16(2), p. 293. Springer 10.1007/s11307-013-0700-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817264ceb8a3b6ed50f6bec7847a8145